Does the Access to Sun Exposure Ensure Adequate Levels of 25-Hydroxyvitamin D?

Damaso, Ênio Luis; Paula, Francisco José Albuquerque de; Franceschini, Sílvio Antônio; Vieira, Carolina Sales; Ferriani, Rui Alberto; Sá, Marcos Felipe Silva de; Lara, Lúcia Alves da Silva

doi:10.1055/s-0037-1600520

Cited by 4 publications

(3 citation statements)

References 48 publications

(77 reference statements)

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“…In general, all techniques measure mainly 25-hydroxy-vitamin D (25-OH-D), because of its long half-life (one month) in plasma. Plasma vitamin D concentrations are conditioned not only by homeostatic regulation but also by lifestyle, environmental and sociocultural factors such as the use of sunscreens, the female gender, postmenopausal status and fat mass [ 24 , 25 , 26 , 27 , 28 ]. During postmenopause, vitamin D supplementation could be recommended in women with confirmed vitamin D deficiency, since it seems to be associated with an increase in bone mineral density and could improve future quality of life [ 29 ].…”

Section: Introductionmentioning

confidence: 99%

Response of Vitamin D after Magnesium Intervention in a Postmenopausal Population from the Province of Granada, Spain

et al. 2020

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Menopause is a stage of hormonal imbalance in women which, in addition to other physiopathological consequences, poses a risk of deficiency of key micronutrients such as magnesium and vitamin D. A study was made of the influence of a magnesium intervention upon vitamin D status in a postmenopausal population from the province of Granada (Spain). Fifty-two healthy postmenopausal women between 44–76 years of age were included. Two randomized groups—placebo and magnesium (500 mg/day)—were treated during eight weeks. Nutrient intake was assessed using questionnaires based on 72-h recall. Vitamin D was analyzed by liquid chromatography—tandem mass spectrometry. Baseline vitamin D proved deficient in over 80% of the subjects. The administration of magnesium resulted in significantly increased vitamin D levels in the intervention group versus the controls (p < 0.05). Magnesium supplementation improved vitamin D status in the studied postmenopausal women.

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Section: Introductionmentioning

confidence: 99%

Response of Vitamin D after Magnesium Intervention in a Postmenopausal Population from the Province of Granada, Spain

et al. 2020

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“…Several factors could influence the level of Vitamin D such as sun exposure, other comorbidites that affect bone and most importantly calcium intake. Current recommendations and daily intakes of vitamin D is at least 1200 mg daily [8].…”

Section: Discussionmentioning

confidence: 99%

High Circulating Sclerostin Level as Osteoporosis Risk Factor in Male Geriatric Population at Sanglah Hospital Bali

Suryarini

Kuswardhani

Wiguna

2021

Open Access Maced J Med Sci

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BACKGROUND: Osteoporosis is a disease characterized by low bone mass and structural deterioration of bone tissue, leading to bone fragility. The development of biomolecular world found Wnt/β-catenin signaling pathway may plays an important role in bone mass regulation. Osteoporosis in geriatric population remains one of global health problems and typically thought of as a disease impacting women, but recently increasing attention is being paid to osteoporosis in males. Osteoporosis in male accounts for higher morbidity and mortality compare to woman population. The association between sclerostin serum and risk for osteoporosis in male geriatric will be described as follows. METHODS: This study is a case–control study with a total 54 samples of male geriatrics, divided into 27 non- osteoporosis subjects and 27 osteoporosis subjects (age ≥60 years old). Diagnosis of osteoporosis was defined according to the WHO criteria based on bone mineral density. All participants were scanned on a GE lunar prodigy bone densitometer. Sclerostin serum level was measured using enzyme-linked immunosorbent assay (ELISA). RESULTS: The average age from total 54 samples in case group was 69.81 ± 6.5 years old and control 69.41 ± 5.97 years old. Cutoff value based on receiver operating characteristic curve for sclerostin serum level was 302.5 pg/mL where the sensitivity and specificity for developing osteoporosis in male geriatrics were 59.3% and 81.5%, respectively. Male geriatrics with sclerostin serum ≥302.5 pg/mL is 6.4 times more likely to developed osteoporosis than those with sclerostin serum <302.5 pg/mL (OR = 6.4; p = 0.0020; CI 95% = 1.856–22.068). Multivariate logistic regression analysis after controlling other variables such as bone mass index, age, smoking status, alcohol consumption, physical activity, sun exposure, and type II diabetes mellitus showed that high sclerostin level was an independent susceptibility factors for osteoporosis in male geriatrics population (p = 0.001). CONCLUSIONS: This study showed that high circulating sclerostin serum (≥302.5 pg/mL) was risk factor for developing osteoporosis in male geriatrics.

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“…1,10,[26][27][28] Brazil has a difficult ethnic classification due to its high degree of miscegenation. 29 As revealed by the 2016 National Continuous Household Sample Survey (PNAD), the Brazilian population is comprised of 8.2% black and 46.2% brown subjects. Thus, most Brazilians present higher phototypes, which could corroborate for the perceived vitamin D deficiency.…”

Section: Reviewmentioning

confidence: 99%

Vitamin D Deficiency in Brazil: Questions about Potential Causes and Clinical Characteristics*

Vieira

Ferreira

Giacomelli

et al. 2021

International Journal of Nutrology

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Vitamin D is a micronutrient essential to various systems from the human body, and it is not restricted to the classical function of bone mineralization. Its synthesis is mainly related to ultraviolet B (UVB) radiation exposure. Although Brazil is a tropical country with high levels of UVB radiation, counter-intuitively, a large number of Brazilians present vitamin D deficiency, which is also a worldwide issue. This review aims to approach clinical features and explore potential causes for this apparent contradiction through questions that could explain vitamin D deficiency in the Brazilian population.

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Does the Access to Sun Exposure Ensure Adequate Levels of 25-Hydroxyvitamin D?

Cited by 4 publications

References 48 publications

Response of Vitamin D after Magnesium Intervention in a Postmenopausal Population from the Province of Granada, Spain

Response of Vitamin D after Magnesium Intervention in a Postmenopausal Population from the Province of Granada, Spain

High Circulating Sclerostin Level as Osteoporosis Risk Factor in Male Geriatric Population at Sanglah Hospital Bali

Vitamin D Deficiency in Brazil: Questions about Potential Causes and Clinical Characteristics*

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