Synchronous Bilateral Warthin Tumors: A Case Report

Abstract

Introduction Warthin tumor is described as papillary cystadenoma lymphomatosum and is the second most common tumor of the parotid glands. Bilateral synchronous incidence is rare, occurring in 7 to 10% of the cases. It is more common in males between 60 and 70 years of age and is closely related to smoking. There is slow growth and the condition is a delimited nodule of regular outlines; it has low rates of malignant progression and recurrence. Objective Report a case of synchronous bilateral Warthin tumor occurring in an elderly patient, and review incidence and peculiarities of this tumor. Case Report A 78-year-old man who used to smoke had a history of mild pain in the topography of right parotid three weeks ago. Patient with hypertension, diabetes and a longtime smoker (smoking a pack per day for 32 years) noticed a progressive bulging in the right parotid region for about 2.5 years ago, and noticed another progressive bulging (althought in the left parotid region), for about one year ago. Patient denied fever, redness, skin lesions and pain during this period until last three weeks, when he sought medical attention for a mild pain in the right facial region. The patient underwent cervical magnetic resonance imaging that showed tumor lesions in both parotids. Fine needle aspiration revealed a typical lesion of epithelial oxyphilic cells associated with reactive lymphoid proliferation, suggesting Warthin tumor. The patient underwent two superficial parotidectomies, and the histopathologic result from both tumors of parotid glands showed papillary cystadenoma lymphomatosum. Conclusion The occurrence of synchronous bilateral Warthin tumor is extremely rare, and anamnesis and physical examination, as well as some complementary examinations, are important means for diagnostic evaluation. Confirmation of the diagnosis can only be obtained through a histopathologic study. A superficial or total parotidectomy is the recommended treatment for the disease.

Beyond Ultrasound: Multimodal Cross-Sectional Imaging for Preoperative Imaging of Parotid Gland Tumors: A Primer for Radiology Trainees

“…WTs are the most common parotid tumor to present as multifocal bilateral nodules, which occurs in up to 10% of cases [17]. They often appear as a slowly progressive parotid gland swelling in older male subjects (typically >60 years) [20][21][22].…”

Bilateral multifocal synchronous intra- and extra-parotid Warthin tumors: case report and review of literature

“…Most of the bilateral tumors are metachronous, with a very few cases of synchronous bilateral tumors reported in the literature. 2,[4][5][6][7] Only one previous case had simultaneous bilateral parotid and neck localizations. 5 We present a rare case of a patient with four bilateral synchronous intra-and extra-parotid Warthin tumors.…”