2014
DOI: 10.1016/j.rbr.2014.06.005
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Perfil epidemiológico da espondiloartrite de início juvenil comparada com a espondiloartrite de início na vida adulta em uma grande coorte brasileira

Abstract: Patients with JOSpA in this large Brazilian cohort were characterized predominantly by male gender, peripheral involvement (arthritis and enthesitis), positive HLA-B27 and lower disease scores.

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Cited by 12 publications
(2 citation statements)
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“…Early genetic association studies in Caucasians showed that HLA-B*27 was present in approximately 90% of the individuals with AS. Further studies confirmed this association in other population, but with different strengths of association; thus, 50-90% of the individuals with this disease have the HLA-B*27 gene ( 5 - 7 ). The HLA-B*27 allelic group has more than 290 known alleles ( 8 ), although most alleles are not associated with AS.…”
Section: Introductionmentioning
confidence: 57%
“…Early genetic association studies in Caucasians showed that HLA-B*27 was present in approximately 90% of the individuals with AS. Further studies confirmed this association in other population, but with different strengths of association; thus, 50-90% of the individuals with this disease have the HLA-B*27 gene ( 5 - 7 ). The HLA-B*27 allelic group has more than 290 known alleles ( 8 ), although most alleles are not associated with AS.…”
Section: Introductionmentioning
confidence: 57%
“…4 As EpAs são mais comumente identificadas na vida adulta, pois é entre a terceira e quarta décadas de vida que majoritariamente os sinais e sintomas clínicos se intensificam. 5 Qualidade de vida é a percepção do indivíduo em relação aos seus objetivos, expectativas, padrões e preocupações envolvendo o bem-estar espiritual, físico, mental e psicológico, além de outras circunstâncias da vida como relacionamentos sociais, saúde e educação. 6 Para classificá-la podem ser usados diferentes tipos de questionários que avaliam respectivamente aspectos genéricos e fatores específicos para cada doença.…”
Section: Introductionunclassified