Dermatoscopia no teste cutâneo da patergia: série de casos de pacientes com suspeita de Doença de Behçet

Scherrer, M; Castro, Lúcia Porto Fonseca de; Rocha, Vanessa Barreto; Pacheco, Lúcia Helena Martins

doi:10.1016/j.rbr.2014.06.003

Cited by 8 publications

(5 citation statements)

References 11 publications

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“…Patients with a disease history of less than 5 years, those with HLA-B51, and cases without treatment tend to have a higher positivity rates. 20 These rates still present an important geographic variation, reaching much higher values in countries alongside the Silk Road, with progressive decline as it moves towards the west.…”

Section: Pathergy Reactionsmentioning

confidence: 99%

“… 21 Surgical sterilization of the site and use of disposable needles were suggested as possible justifications for this reduction. 20 However, the cause remains unclear. 21 …”

Section: Pathergy Reactionsmentioning

confidence: 99%

“…A study performed in Brazil showed a 91.3% positivity rate in 23 patients with a diagnosis of BD. 20 In this study, the test was performed in four distinct regions of the forearm and, with the aid of clinical and dermoscopic examination, the area with the highest evidence of tissue reaction was biopsied.…”

Section: Pathergy Reactionsmentioning

confidence: 99%

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Behçet's disease: review with emphasis on dermatological aspects

Scherrer

Rocha

Garcia

2017

An. Bras. Dermatol.

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Behçet's disease is a systemic vasculitis characterized by attacks of acute inflammation, which can affect almost every vascularized area of the body. There is a close correlation between the geographical distribution of HLA-B51 and its prevalence. In the etiopathogenesis there are indications of genetic susceptibility associated with environmental influence. Among the involved genes are those that encompass innate and adaptive immunities. Polymorphisms and epistatic interactions in several genes are described, as well as the presence of imbalance lineage between HLA-B51 and A (MICA). Herpes simplex and Streptococcus sanguinis may be important extrinsic factors. An increase of Th1 response and of IL-21 is observed. The production of IL-21 is positively related to Th17 cells and negatively to T-regs. The mucocutaneous manifestations are Behcet´s disease markers, and their earlier onset indicates a worse prognosis. Recurrent oral ulcers have varied sizes and arrangements, genital ulcers are recurrent, leaving scars, skin lesions are multivaried, and pathergy, although not so frequent, is important for the diagnosis. There are numerous attempts to validate indexes that can evaluate the disease activity and among them the Mucocutaneous Activity Index. This is a specific score that can help with therapeutic decisions and to reduce morbidity, but still lacks validation. The clinical manifestations of other organs are described as well as treatment options.

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Section: Pathergy Reactionsmentioning

confidence: 99%

“… 21 Surgical sterilization of the site and use of disposable needles were suggested as possible justifications for this reduction. 20 However, the cause remains unclear. 21 …”

Section: Pathergy Reactionsmentioning

confidence: 99%

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Behçet's disease: review with emphasis on dermatological aspects

Scherrer

Rocha

Garcia

2017

An. Bras. Dermatol.

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“…However the pathergy phenomenon is not constant during the course of the disease. The degree of positivity may occasionally correlate with disease activity [ 9 ]. The present case did not show a positive pathergy phenomenon.…”

Section: Discussionmentioning

confidence: 99%

Low Level Laser Therapy to Reduce Recurrent Oral Ulcers in Behçet’s Disease

Babu

Chavva

Waghray

et al. 2016

Case Reports in Dentistry

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Behçet's disease (BD) is a chronic, relapsing multisystemic vascular condition. Behçet's disease was described by Hulusi Behçet in 1937. This rare multisystem relapsing-remitting inflammatory disease is poorly understood but is thought to be an autoimmune inflammatory vasculitic process in a genetically predisposed population. Diagnosis of Behçet's disease is based on International Criteria of Behçet's Disease (ICBD). The present paper describes a case report of Behçet's syndrome where aphthous stomatitis was treated with low level laser therapy.

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“…Em geral, consiste de diferentes combinações de manifestações oculares, neurológicas, cardiovasculares, gastrintestinais e outras. 3 Afeta tipicamente adultos jovens entre os 20 aos 40 anos. 4 É caracterizada por úlceras orais e genitais recorrentes, uveíte, artrite e lesões de pele, como eritema nodoso ou pseudofoliculite.…”

Section: Introductionunclassified

Aneurisma de artéria pulmonar como apresentação clínica de uma doença de Behçet: a propósito de um caso

et al. 2022

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Objetivo: Apresentar aspectos clínicos e alterações radiológicas observados em um caso de doença de Behçet. Metodologia: A pesquisa foi realizada através da investigação de um paciente com diagnóstico de doença de Behçet apresentando aneurisma de artéria pulmonar. Descrição do caso: Paciente com história de úlceras orais e genitais dolorosas recorrentes. Apresentou quadro de edema e dor em região cervical, sendo diagnosticado com trombose de veia jugular interna e braquiocefálica direita. Evoluiu com quadro de dispneia, dor torácica, hemoptise, hematêmese, sendo diagnosticado aneurisma de artéria pulmonar, além de apresentar úlceras dolorosas, sendo diagnosticado doença de Behçet. Discussão: Pela classificação do International Study Group for Behçet’s Disease, a presença de úlceras orais recorrentes e mais duas das seguintes alterações - úlceras genitais, lesões oculares típicas (uveíte, vasculite retinal), lesões de pele características, ou um teste de patergia positivo definem o diagnóstico da doença de Behçet. Ainda que seja uma manifestação rara, atingindo menos de 5% dos doentes, o envolvimento da artéria pulmonar é a forma de complicação vascular mais temida. Conclusão: Podemos concluir que é importante considerar o diagnóstico de Behçet, pois essa patologia pode afetar diversos vasos de qualquer calibre no organismo, podendo resultar em tromboflebite, estenose arterial, oclusões e aneurismas.

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Dermatoscopia no teste cutâneo da patergia: série de casos de pacientes com suspeita de Doença de Behçet

Cited by 8 publications

References 11 publications

Behçet's disease: review with emphasis on dermatological aspects

Behçet's disease: review with emphasis on dermatological aspects

Low Level Laser Therapy to Reduce Recurrent Oral Ulcers in Behçet’s Disease

Aneurisma de artéria pulmonar como apresentação clínica de uma doença de Behçet: a propósito de um caso

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