Avaliação do comprometimento respiratório em pacientes com lúpus eritematoso sistêmico com o teste de caminhada de seis minutos

Leite, Marivone Arruda; Pereira, Mônica Corso; Costallat, Lílian Tereza Lavras; Villalba, Wander de Oliveira; Moreira, Marcos Mello; Paschoal, Ilma Aparecida

doi:10.1016/j.rbr.2014.02.004

Cited by 2 publications

(2 citation statements)

References 28 publications

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“…The six-min walk test (6MWT) is a submaximal exercise test that allows evaluation of several lung diseases (22). The protocol was performed in a walking course with 30 m of length.…”

Section: Methodsmentioning

confidence: 99%

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Biomass smoke COPD has less tomographic abnormalities but worse hypoxemia compared with tobacco COPD

Meneghini

Koenigkam-Santos

Pereira

et al. 2019

Braz J Med Biol Res

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Special attention has emerged towards biomass smoke-induced chronic obstructive pulmonary disease (COPD), providing new knowledge for prevention and therapeutic approach of non-smoker COPD patients. However, the understanding of biomass smoke COPD is still limited and somewhat controversial. The aim of the present study was to compare COPD exclusively caused by tobacco smoking with COPD exclusively caused by environmental or occupational exposures. For this cross-sectional study, COPD patients were recruited from outpatient clinics and formed two groups: non-smoker COPD group (n=16) with exposure to biomass smoke who did not smoke cigarette and tobacco smoker COPD group (n=15) with people who did not report biomass smoke exposure. Subjects underwent pulmonary function tests, thoracic high-resolution computed tomography, 6-min walk test, and sputum induction. The non-smoker COPD group had biomass smoke exposure of 133.3±86 hour-years. The tobacco COPD group smoked 48.5±27.4 pack-years. Women were 62.5 and 66.7%, respectively, of non-smokers and smokers. The non-smoker COPD group showed higher prevalence of dyspnea, lower arterial oxygen tension (PaO 2 ), and lower arterial oxygen saturation (SaO 2 %) with similar spirometry results, lung volumes, and diffusion capacity. Regarding inflammatory biomarkers, differences were detected in sputum number of lymphomononuclear cells and in sputum concentrations of interleukin (IL)-6 and IL-8 with higher values in the smoker group. Emphysema was more prevalent in the tobacco smoker group, which also showed higher relative bronchial wall thickness and lower lung density by quantitative analysis. Biomass smoke induced more hypoxemia compared to tobacco in COPD patients with similar severity.

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“…The six-min walk test (6MWT) is a submaximal exercise test that allows evaluation of several lung diseases (22). The protocol was performed in a walking course with 30 m of length.…”

Section: Methodsmentioning

confidence: 99%

“…Questionnaires were employed for dyspnea evaluation, socioeconomic status characterization, COPD severity assessment, other symptoms, and exposure evaluation (22–26).…”

Section: Methodsmentioning

confidence: 99%

Biomass smoke COPD has less tomographic abnormalities but worse hypoxemia compared with tobacco COPD

Meneghini

Koenigkam-Santos

Pereira

et al. 2019

Braz J Med Biol Res

View full text Add to dashboard Cite

show abstract

Avaliação pulmonar funcional, tomográfica e de escores de gravidade de crianças e adolescentes com lúpus eritematoso sistêmico juvenil (LESJ)

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Avaliação do comprometimento respiratório em pacientes com lúpus eritematoso sistêmico com o teste de caminhada de seis minutos

Abstract: Compared to 6MWD, desaturation was better suited to find the patients with the most compromised indexes in respiratory function tests.

Cited by 2 publications

References 28 publications

Biomass smoke COPD has less tomographic abnormalities but worse hypoxemia compared with tobacco COPD

Biomass smoke COPD has less tomographic abnormalities but worse hypoxemia compared with tobacco COPD

Avaliação pulmonar funcional, tomográfica e de escores de gravidade de crianças e adolescentes com lúpus eritematoso sistêmico juvenil (LESJ)

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