Infecção por parvovírus B19 como causa de miosite aguda em um adulto

Abstract

Parvovirus B19 infection is often asymptomatic, but clinical expressions may include transient aplastic crisis, erythema infectiosum, non-immune hydrops fetalis, and chronic red cell aplasia. This virus has also been associated with rheumatoid arthritis and other autoimmune connective tissue diseases; however, we could not identify any acute adult myositis case developed after a Parvovirus B19 infection in the literature. For this reason, we would like to present a rare case of acute myositis developed after Parvovirus B19 infection. In patients presenting with symptoms of fever, rash on the legs and myositis, viral infections such as Parvovirus B19 should be kept in mind.

Human Parvoviruses

“…B19V infection can occur in patients with leukemia, especially during or after chemotherapy, producing the expected reticulocytopenia (794)(795)(796)(797). Its significance in other respects, especially for pathogenesis, is unclear (6,798). Viral infection preceding presentation with acute lymphoblastic leukemia has been observed (799, 800).…”

“…The presence of replicative intermediate B19V DNA forms (857)(858)(859) and B19V capsid protein in biopsy specimens has been reported (860), but B19V viral loads have not correlated with outcomes (861). Myositis affecting muscles other than the heart is rarely associated with B19V (798).…”