Characterization of hip and knee arthroplasties and factors associated with infection

Pinto, Cibele Zdebsky da Silva; Alpendre, Francine Taporosky; Stier, Christiane Johnscher Niebel; Maziero, Eliane Cristina Sanches; Alencar, Paulo Gilberto Cimbalista de; Cruz, Elaine Drehmer de Almeida

doi:10.1016/j.rboe.2015.09.004

Cited by 6 publications

(9 citation statements)

References 17 publications

(26 reference statements)

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“…Brazilian researchers 11 showed that females were preferentially affected among patients with TKA infection, with a prevalence of 65.51%, a result similar to the present study (69.23%). Furthermore, we found a significant associations of TKA infection with the age over 65 years (p = 0.023), unlike the results of Pinto et al, 19 which found no statistically significant association. Five patients (6.17%) submitted to TKA developed deep vein thrombosis and three of them had infection (p = 0.027), a much higher rate than that observed by Lenza et al 4 and Xu et al 17 Only one patient of this study had died, almost half the prevalence found by Pinto et al; 19 however, higher than Lenza et al, 4 who had no deaths among patients undergoing TKA.…”

Section: Discussioncontrasting

confidence: 99%

“…Just as diabetes mellitus , rheumatic diseases had a similar prevalence (15.38%) among patients with TKA infection, but there was no statistically significant association. Only one patient had rheumatoid arthritis among those infected, however, considering all 81 arthroplasties, 6.17% had rheumatoid arthritis, five times more prevalent than in the study by Lenza et al, 4 and almost three times more prevalent than in the study by Pinto et al 19 …”

Section: Discussionmentioning

confidence: 59%

“…The level of TKA infection of this study (16.04%) was higher than others found in the literature. 13 - 16 , 19 , Moreover, the level of superficial infections was up to five times higher, and deep infections exceeded the level found in the national 4 , 19 and international literature. 17…”

Section: Discussionmentioning

confidence: 67%

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Clinical Demographic Characteristics of Total Knee Arthroplasty in a University Hospital

et al. 2016

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Objective: To assess socio-demographic characteristics of patients undergoing total knee arthroplasty (TKA) in a public university hospital, evaluating the outcome infection and associated factors. Method: A retrospective study was carried out with 78 patients undergoing TKA, from 2013 to 2014. The socio-demographic and clinical characteristics of the patients were collected. Comparison between infected and non-infected patients was performed to find out which variables were possibly associated to this complication. Result: Of 81 arthroplasties performed, patients were older (mean age 64 years), women (79%), with primary osteoarthritis as main etiology (87.6%) and most had comorbidities (82.7%). Infection occurred in 16% of patients, and this outcome associated with age older than 65 years (p=0.023) and the occurrence of deep vein thrombosis (p=0.027). Conclusion: Patients undergoing TKA are mostly elderly women with primary osteoarthritis in the knee and comorbidities who developed infection in 16% of cases. More studies need to be conducted aimed at creating specific protocols in order to improve the quality of clinical practice. Level of Evidence III, Retrospective Comparative Study.

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Section: Discussioncontrasting

confidence: 99%

Section: Discussionmentioning

confidence: 59%

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Clinical Demographic Characteristics of Total Knee Arthroplasty in a University Hospital

et al. 2016

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“…Surveillance: clinical records review type Direct 92 Akhter et al (2016), Al-Mulhim et al (2014), Ali et al (2009), Alvarez-Moreno et al (2014), Ameh et al (2009), Atif et al (2015), Austin et al (2004), Bannura et al (2016), Bellusse et al (2015), Bercion et al (2007), Bibi et al (2015), Buang and Haspani (2012), Cao et al (2017), Ikeanyi et al (2013), da Cunha et al (2011, da Silva Pinto et al (2015), De Nardo et al (2016, Ding et al (2014), Ding et al (2016), Dreher et al (2017), Duerink et al (2006), Ee et al (2014), El Beltagy et al (2010), Farouk et al (2015), Farsky et al (2011), Fehr et al (2006), Freitas et al (2000), Galal and El-Hindawy 2011 The study type and follow-up time of surveillance after the index procedure (postoperative) expressed in months were also recorded, as were any explicit description of a post-discharge surveillance period and the frequencies of SSI at each stage. The final variable evaluated was whether the procedures included the placement of some type of artificial implant, in all or at least some of the surgeries.…”

Section: Topic Number Referencementioning

confidence: 99%

Surgical site infection in elective clean and clean-contaminated surgeries in developing countries

Curcio

Cané

Fernández³

et al. 2019

International Journal of Infectious Diseases

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Background: Surgical site infection (SSI) is both the most frequently studied healthcare-associated infection and the most common healthcare-associated infection in the developing world. A systematic review and meta-analysis was conducted to evaluate the relative size of this burden and to estimate the prevalence of SSI in clean and clean-contaminated surgeries in a large sample of countries in the developing world. Methods: A systematic search of the MEDLINE/PubMed, Scopus, and LILACS databases was conducted to identify studies providing the prevalence of SSI in elective clean and clean-contaminated surgeries in 39 countries or regions around the world. Data of interest were limited to publications from January 2000 to December 2017. Studies with information on the number of cases of SSI and number of total elective clean and clean-contaminated surgeries during the same period were included in this evaluation. Studies lacking clear definition of the total number of exposed patients were excluded. Results: Based on the combined data from the 99 articles evaluated in this analysis, the overall prevalence of SSI in elective clean and clean-contaminated surgeries was estimated to be 6% (95% confidence interval (CI) 5-7%). This increased to 15% (95% CI 6-27%) when considering only those reports with post-discharge surveillance data. The overall prevalence of SSI in Africa/Middle East, Latin America, Asia, and China was 10% (95% CI 6-15%), 7% (95% CI 5-10%), 4% (95% CI 4-5%), and 4% (95% CI 2-6%), respectively. Significant variability in the data was confirmed by both the funnel plot and the Egger test (p = 0.008). Conclusions: Although the data are variable, it is clear that the incidence of SSI in the developing world is higher than that in the developed world.

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“…Thus, prophylaxis with ND for MRSA may be indicated as an important prophylactic method for periprosthetic joint infection. 16 , 17 However, studies that analyzed this subject did not reach a consensus in the validation of prophylaxis through universal MRSA assessment in TKA and THA candidates. 2…”

Section: Introductionmentioning

confidence: 99%

Prophylaxis with nasal decolonization in patients submitted to total knee and hip arthroplasty: systematic review and meta-analysis

Sadigursky

Pires

Rios

et al. 2017

Revista Brasileira de Ortopedia (English Edition)

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Despite the evolution of the total knee and hip arthroplasty surgery, high postoperative complication rates in the short and long term still persist. Infection is one of the most challenging complications; due to its gravity and treatment difficulties, prophylaxis protocols have been created to decrease its incidence. The objective of this study was to evaluate the impact of the prophylaxis protocol for methicillin-resistant Staphylococcus aureus decolonization of the nares in patients previously identified by swab cultures, who were to be submitted to a total joint arthroplasty. A systematic review with meta-analysis was conducted, following the PRISMA-2015 protocol, using the descriptors: “arthroplasty” and “nasal decolonization,” or “joint arthroplasty” and “decolonization,” or “joint arthroplasty” and “nasal decolonization,” for final selection of four observational studies from 79 references identified. This study included a total sample of 10,179 patients, divided in two groups: the control group (4788 patients) and intervention group (5391 patients). It was observed that the intervention group, in which prophylaxis with nasal decolonization was used, 59 (1.09%) of the patients developed a surgical site infection, while in the control group there were 86 cases of surgical site infection (1.79%). This trend repeated itself in all articles, showing no publication biases, forming a homogeneous sample. The use of a prophylaxis protocol for decolonization of methicillin-resistant Staphylococcus aureus, reduced surgical site infection cases by approximately 39%.

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Characterization of hip and knee arthroplasties and factors associated with infection

Cited by 6 publications

References 17 publications

Clinical Demographic Characteristics of Total Knee Arthroplasty in a University Hospital

Clinical Demographic Characteristics of Total Knee Arthroplasty in a University Hospital

Surgical site infection in elective clean and clean-contaminated surgeries in developing countries

Prophylaxis with nasal decolonization in patients submitted to total knee and hip arthroplasty: systematic review and meta-analysis

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