Parental, gestational, and early-life exposure to indoor environmental hazardous factors on allergic rhinitis among preschool children in Urumqi City: a case-control study

Wang, Tingting; Shi, Haonan; Qi, Huizhen; Jiang, Lan; Lin, Yuting; Jian, Yao; Lu, Junwen; Yan, Qi; Zhu, Aiyong; Yao, Xuan

doi:10.1016/j.jped.2022.09.005

Cited by 2 publications

(1 citation statement)

References 26 publications

(25 reference statements)

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“…Hainan region is located in the tropics, perennial high temperature and high humidity climate, will lead to the indoor environment of the humid situation, and indoor quilts and clothes in the humid environment will be moldy as well as damage. In addition, with the change of people's lifestyles and Hainan's hightemperature environment, resulting in children's indoor activity time increases, long time in the closed space, it will be easy to come into contact with indoor dust mites, mold and other allergens, thus increasing the possibility of children's AR disease 13 . Therefore, this study was conducted in January 2021 to study Chinese Child and Home Health (CCHH) in 8 kindergarten preschool children in 4 districts of Haikou City, Hainan Province, China.…”

Section: Introdutionmentioning

confidence: 99%

Associations of Early-Life Exposure indoor environment with preschool children allergic rhinitis: A case-control study in Haikou city

Wu,

Fan,

Zhou

et al. 2024

Preprint

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Objective: The study aimed to examine the association between allergic rhinitis and early-life indoor environmental exposure in preschool children in Haikou City, providing a scientific theoretical basis for the prevention of allergic rhinitis in this population. Methods: In January 2021, we conducted the China Child and Home Health (CCHH) study using a case-control approach with 1090 preschool children in Haikou City, Hainan Province, including 218 cases and 872 controls. The study included baseline demographic information, residential and indoor environmental characteristics, living habits, and children's allergies. Two-level logistical regression analysis was used to examine the association of Early-Life Exposure indoor environment with preschool children allergic rhinitis in terms of odds ratio (OR) and 95% confidence interval (CI). Results: Mother with an educational level of university or above (OR=1.443, 95% CI=1.024~2.035), having parental atopy (OR=4.604, 95% CI=3.339~6.349), damages or molds found in the mother's residence prior to pregnancy (OR=1.613, 95% CI=1.044~2.493), and passive smoking of the mother during pregnancy (OR=1.833, 95% CI=1.282~2.623) were risk factors for allergic rhinitis in preschool children. Conclusions: In this case-control study, we found significant associations between parental atopy, mother's education, and indoor environment in early life with the development of allergic rhinitis in preschool children. Therefore, prophylactic measures should be actively implemented in preschool children with allergic parental atopy, as well as preventing the mother's exposure to harmful factors in the indoor environment before and during pregnancy.

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Section: Introdutionmentioning

confidence: 99%

Associations of Early-Life Exposure indoor environment with preschool children allergic rhinitis: A case-control study in Haikou city

Wu,

Fan,

Zhou

et al. 2024

Preprint

View full text Add to dashboard Cite

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Perinatal Risk Factors for Asthma and Allergic Rhinitis in Children and Adolescents

Hwang,

Shin,

Stybayeva

et al. 2024

Clin Exp Otorhinolaryngol

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Objectives. In this study, we evaluated the associations between birth-related exposures, postnatal factors, and the risk of allergic rhinitis and asthma in children and adolescents.Methods. We performed a comprehensive search of five literature databases up to May 2023. To quantify the associations of birth-related exposures (birth weight, delivery mode, prematurity, sex, maternal age, and parental allergy history) and postnatal factors (birth order, number of siblings, breastfeeding exclusivity, and breastfeeding duration) with allergic disease, we calculated pooled odds ratios and 95% confidence intervals. We conducted subgroup analyses for allergic disease type, birth order, number of siblings, and parental allergy history. The methodological quality of the identified studies was evaluated using the Newcastle-Ottawa Scale.Results. This meta-analysis included 31 studies, encompassing 218,899 patients in total. The birth-related exposures of low birth weight, maternal age, and prematurity (less than 37 weeks gestation) were not significantly associated with the risk of asthma or allergic rhinitis during childhood or adolescence. Male sex, family history of allergy, and cesarean delivery were linked to an elevated risk of asthma or allergic rhinitis. Among postnatal factors, exclusive breastfeeding, breastfeeding for longer than 6 months, second or later birth order, and having siblings exhibited protective effects against allergic diseases in offspring.Conclusion. The risks of allergic rhinitis and asthma were elevated in male patients, those delivered by cesarean section, and those with a family history of allergy. Conversely, exclusive breastfeeding, breastfeeding for longer than 6 months, and having siblings corresponded to a reduced risk of respiratory allergic diseases.

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Parental, gestational, and early-life exposure to indoor environmental hazardous factors on allergic rhinitis among preschool children in Urumqi City: a case-control study

Cited by 2 publications

References 26 publications

Associations of Early-Life Exposure indoor environment with preschool children allergic rhinitis: A case-control study in Haikou city

Associations of Early-Life Exposure indoor environment with preschool children allergic rhinitis: A case-control study in Haikou city

Perinatal Risk Factors for Asthma and Allergic Rhinitis in Children and Adolescents

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