Zero tolerance for asthma deaths in children

Fiocchi, Alessandro; Valluzzi, Rocco; Dahdah, Lamia

doi:10.1016/j.jped.2019.07.002

Cited by 3 publications

(2 citation statements)

References 19 publications

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“…On the other hand, the mortality rates for children under 5 years old were relatively higher than those for the other children and adolescents. As stated in previous studies, there is no greater cost than the preventable death of an asthma patient, especially among children [ 16 , 17 ]. Recent studies have demonstrated that asthma in children is increasingly prevalent in China [ 18 ].…”

Section: Discussionmentioning

confidence: 94%

Long-Term Trends of Asthma Mortality in China from 2000 to 2019: A Joinpoint Regression and Age-Period-Cohort Analysis

Huang¹,

Liu²,

Li³

et al. 2022

Healthcare

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Background: Trends of asthma mortality vary widely all over the world, while the trends in China over the past 15 years are unknown. The aim of this study was to assess the trends of asthma mortality in China. Methods: Asthma deaths and demographic characteristics were collected from National Death Cause Datasets of Disease Surveillance System between 2004 and 2019. The data were analyzed with joinpoint regression analysis and age-period-cohort (APC) analysis for the mortality rate due to asthma in China. Results: Asthma mortality declined from 2.4 (95% confidence interval (CI): 2.3–2.5) per 100,000 in 2004 to 1.6 (95% CI: 1.5–1.7) per 100,000 in 2019. Age-adjusted asthma mortality rates decreased for men and women in urban and rural areas from 2004 through 2019. The decreasing trend of the mortality rate has slowed down substantially during 2007 and 2009. After that, the decreasing trend has stabilized. The asthma mortality rates generally have a positive relationship with the age of the population when controlling for period and cohort. The period trend decreased and then increased when controlling for age and cohort. Conclusions: We should pay more attention to asthma management plans or treatment for aging people who are facing higher risk of asthma death.

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Section: Discussionmentioning

confidence: 94%

Long-Term Trends of Asthma Mortality in China from 2000 to 2019: A Joinpoint Regression and Age-Period-Cohort Analysis

Huang¹,

Liu²,

Li³

et al. 2022

Healthcare

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“…This form of asthma is subject to significant heterogeneity ( 7 ). Predictors of poor outcomes are still largely unknown ( 8 ), but children with asthma grade 1–4 are subject to reduced lung function ( 9 ), abnormal patterns of lung growth ( 10 ), risk of chronic obstructive pulmonary disease in adulthood ( 11 ), severe exacerbations ( 12 ), and even fatalities ( 13 ). This may be increased by the lower compliance to regular controller medication compared to severe asthma ( 14 ).…”

Section: Introductionmentioning

confidence: 99%

Doxofylline for Pediatric Asthma Steps 1–4. Pediatric Asthma: New Role for an Old Drug

et al. 2022

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The panoply of anti-asthma drugs for children between 6 and 18 years is not limited to those reported in the guidelines. In this review, we will re-assess the role of doxofylline, a xanthine characterized by a much higher handling than that of theophylline, as add-on treatment in pediatric asthma grade 1–4. Ten studies evaluated doxofylline in the treatment of asthma of patients non-responsive to the first-line inhaled corticosteroids. Of these, two included children and one was exclusively pediatric. According to their results, doxofylline exerts a powerful bronchodilator and anti-inflammatory activity, which can be exploited when the inhaled oral corticosteroids are not sufficient to get the desired effect of reducing symptoms. Unlike theophylline, doxofylline does not require blood testing. It can be administered together with or as an alternative to a series of other drugs considered in additional therapy.

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Asthma mortality among children and adolescents in China, 2008–2018

Shen

2022

World J Pediatr

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Zero tolerance for asthma deaths in children

Cited by 3 publications

References 19 publications

Long-Term Trends of Asthma Mortality in China from 2000 to 2019: A Joinpoint Regression and Age-Period-Cohort Analysis

Long-Term Trends of Asthma Mortality in China from 2000 to 2019: A Joinpoint Regression and Age-Period-Cohort Analysis

Doxofylline for Pediatric Asthma Steps 1–4. Pediatric Asthma: New Role for an Old Drug

Asthma mortality among children and adolescents in China, 2008–2018

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