Cholelithiasis in obese adolescents treated at an outpatient clinic

Nunes, Marília Mendes; Medeiros, Carla Campos Muniz; Silva, Luciana Rodrígues

doi:10.1016/j.jped.2013.08.008

Cited by 6 publications

(6 citation statements)

References 23 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…14 Obesity not only risk factor for GSD in adults but it also reported as independent risk factor in adolescents and young age group. 15 In present study 49.3% of patients was < 40 years, while in a study conducted by Shafique et al: almost half (48.13%) of their patients were younger than 30 years. 16 The present study revealed that GSD high prevalence in non-working women as compare to working women (80.2%Versus19.8%), while in study by Alishi YA et al; 14 the ratio was 44.2% vs 55.8% respectively.…”

Section: Resultscontrasting

confidence: 48%

Gall bladder stones disease– prediction constructs calculator.

Mehboob

Ahmed

Khosa

et al. 2022

TPMJ

View full text Add to dashboard Cite

Objective: The objective was to calculate the constructs and determine the predictors of gall bladder stone disease. Study Design: Randomized Control study. Setting: Mohtarma Shaheed Benazir Bhutto Hospital and Sandeman Provincial Teaching Hospital Quetta. Period: 2019 to 2020. Material & Methods: A total of 392 patients were enrolled by non-probability consecutive technique from outpatient department and those referred from medicine department. The inclusion criteria were patients of any age group and gender. The exclusion criteria were the patients who were physically handicap interfering with anthropometric indices and patients suffering from hemolytic disease. The patients were divided into two groups, the disease group (patients having gall bladder stone) were 207 patients and control group (patients without gall bladder stone) were 185 patients. In all patients’ anthropometric indices and lipid profile was performed. The data was collected on prescribed proforma. The constructs were analyzed by using SPSS version 23. Results: The overall mean age of the patients was 43.97 +11.75 years. There were 355 (90.6%) female and 37 (9.4%) male. The height and weight were found significant in female patients (p – 0.012 & < 0.001 respectively). The waist circumference was significant in male (p – 0.017), while hip circumference and waist to hip ratio in female (p -0.015 & <0.001 respectively). The body mass index was above normal in female 122 (62.1%), while in male patients 7 (62.3%) in disease category. In female patients with high risk cholesterol group had 1.5 times more risk than desirable group and low level of HDL had 4 times more risk than normal level. In male patients with elevated LDL was statistically significant. Conclusion: Gall bladder stone disease predictors determinants are female in their late forties or early fifties, raised body mass index, hip circumference and waist to hip ratio and elevated cholesterol level, while male in their late forties or early fifties, raised waist circumference and elevated LDL & Triglycerides.

show abstract

Section: Resultscontrasting

confidence: 48%

Gall bladder stones disease– prediction constructs calculator.

Mehboob

Ahmed

Khosa

et al. 2022

TPMJ

View full text Add to dashboard Cite

show abstract

“…Obesity‐related non‐alcoholic steatohepatitis and cholelithiasis share common risk and pathogenic factors. According to previous studies, the rate of cholelithiasis among obese adolescents is 2–6.4% . Obesity prevalence ranges from 3.7% to 4.5% in Turkish school children .…”

Section: Discussionmentioning

confidence: 97%

“…The prevalence of cholelithiasis among children is 0.13–0.3% . However, in obese children and adolescents, the prevalence of cholelithiasis is as high as 2–6.1% . The aetiology remains idiopathic in 30–54% of children.…”

mentioning

confidence: 99%

“…Haemolytic disease and non‐haemolytic disorders, such as cystic fibrosis, obesity, drugs and total parenteral nutrition (TPN), are common associated risk factors . Cholelithiasis may be asymptomatic, or it may present with nonspecific symptoms, cholecystitis, pancreatitis and obstructive jaundice in children . There is no consensus on follow‐up care and management of cholelithiasis in children.…”

mentioning

confidence: 99%

See 1 more Smart Citation

Risk factors, complications and outcome of cholelithiasis in children: A retrospective, single‐centre review

Kırşaçlıoğlu

Çakır

Bayram

et al. 2016

J Paediatrics Child Health

View full text Add to dashboard Cite

A total of 254 children with cholelithiasis (mean age: 8.9 ± 5.2 years) were recruited to the study. Girls (52.8%) were significantly older than boys (P < 0.001). Symptomatic patients (59%) were significantly older than asymptomatic patients (P = 0.002). Abdominal pain was the most frequent symptom. No risk factors were identified in 56.6% of the patients. Ceftriaxone (20%) was the most commonly associated risk factor. At presentation, at least one of the following complications was seen in 14.1% of patients: cholecystitis (10.9%), obstructive jaundice (2.7%), pancreatitis (1.96%) and cholangitis (1.2%). There was no relationship between gallstone size and symptoms, aetiological factors and complications. The cholelithiasis dissolution rate was higher in younger children (P = 0.032), in those with biliary sludge (P < 0.0001) and ceftriaxone-related cholelithiasis (P < 0.001). Haemolytic anaemia (P = 0.001) and older age (P = 0.002) were associated with stable stones. Ursodeoxycholic acid was administered to 94.4% of patients at presentation. Twenty-nine patients underwent cholecystectomy, and seven patients underwent endoscopic retrograde cholangiopancreotography. Patients who were symptomatic at presentation had significantly more frequent symptoms at follow-up (P < 0.001) CONCLUSIONS: Dissolution rate of cholelithiasis was higher in younger children, biliary sludge formation and ceftriaxone-related cholelithiasis but lower in older children and haemolytic anaemia-related cholelithiasis.

show abstract

“…The prevalence of cholelithiasis in healthy children, determined by abdominal ultrasound, is estimated to be 1.9%, whereas the prevalence of biliary dyskinesia in children is unknown (13). The prevalence of gallbladder disease leading to surgery in healthy children is reported to be 2% to 4%, but may be as high as 6% in obese children (13)(14)(15)(16). In the present study, we surveyed a representative sample of girls and young women who participated in the Natural History of Rett Syndrome study throughout the United States to estimate the prevalence of biliary tract disease in this disorder.…”

Section: Discussionmentioning

confidence: 99%

Biliary Tract Disease in Girls and Young Women With Rett Syndrome

Motil

Lane

Barrish³

et al. 2019

J. pediatr. gastroenterol. nutr.

View full text Add to dashboard Cite

Objective: We reviewed medical records and conducted a nationwide survey to characterize the clinical features and determine the prevalence of biliary tract disease in girls and women with Rett syndrome (RTT). Methods: Sixty-two individuals with RTT and biliary tract disease were identified from the membership of Rett Syndrome Organization (RS.O) and patient files of the principal investigator. Medical records of 46 individuals were reviewed for presenting features, diagnostic tests, and treatment outcomes of biliary tract disease. We designed a questionnaire that probed the frequency of risk factors and treatment outcomes of biliary tract disease in RTT. The questionnaire was completed by 271 parents whose daughters met the clinical criteria for RTT and/or had MECP2 mutations and participated in the Natural History of Rett Syndrome Study. Results: Presenting symptoms identified by record review included abdominal pain (94%), irritability (88%), weight loss (64%), and vomiting (52%). Biliary dyskinesia, cholecystitis, and cholelithiasis, were identified in 90%, 77%, and 70%, respectively, by cholescintigraphy, surgical pathology, and abdominal ultrasound. The prevalence of biliary tract disease was 4.4% (n=12) in the RTT cohort. Risk factors included older age (p<0.001) and a positive family history (p<0.01).

show abstract

Cholelithiasis in obese adolescents treated at an outpatient clinic

Abstract: cholelithiasis and hepatic steatosis are frequent among obese adolescents and should be investigated systematically in the presence or absence of symptoms.

Cited by 6 publications

References 23 publications

Gall bladder stones disease– prediction constructs calculator.

Gall bladder stones disease– prediction constructs calculator.

Risk factors, complications and outcome of cholelithiasis in children: A retrospective, single‐centre review

Biliary Tract Disease in Girls and Young Women With Rett Syndrome

Contact Info

Product

Resources

About