Comparison of six-minute walk test in children with moderate/severe asthma with reference values for healthy children

Andrade, Lívia Barboza de; Silva, Diogo A.R.G.; Salgado, Taíza L.B.; Figueroa, José Natal; Lucena‐Silva, Norma; Britto, Murilo Carlos Amorim de

doi:10.1016/j.jped.2013.08.006

Cited by 35 publications

(30 citation statements)

References 26 publications

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“…In contrast, Andrade et al compared physical and cardiorespiratory performance in the six-minute walk test (6MWT) in 40 children with moderate and severe asthma (6-16 years of age) and found that, regarding quality of life assessment, the PAQLQ activity limitation domain had the worst scores and correlated negatively with difference in distance walked. 31 The authors concluded that the performance of the asthma patients in the 6MWT, as evaluated on the basis of distance walked, was significantly lower than the predicted values for healthy individuals of the same age group. 31 )…”

Section: Discussionmentioning

confidence: 92%

Evaluation of quality of life according to asthma control and asthma severity in children and adolescents

et al. 2015

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OBJECTIVE: To evaluate quality of life according to the level of asthma control and degree of asthma severity in children and adolescents. METHODS: We selected children and adolescents with asthma (7-17 years of age) from the Pediatric Pulmonology Outpatient Clinic of the State University of Campinas Hospital de Clínicas, located in the city of Campinas, Brazil. Asthma control and asthma severity were assessed by the Asthma Control Test and by the questionnaire based on the Global Initiative for Asthma, respectively. The patients also completed the Paediatric Asthma Quality of Life Questionnaire (PAQLQ), validated for use in Brazil, in order to evaluate their quality of life. RESULTS: The mean age of the patients was 11.22 ± 2.91 years, with a median of 11.20 (7.00-17.60) years. We selected 100 patients, of whom 27, 33, and 40 were classified as having controlled asthma (CA), partially controlled asthma (PCA), and uncontrolled asthma (UA), respectively. As for asthma severity, 34, 19, and 47 were classified as having mild asthma (MiA), moderate asthma (MoA), and severe asthma (SA), respectively. The CA and the PCA groups, when compared with the NCA group, showed higher values for the overall PAQLQ score and all PAQLQ domains (activity limitation, symptoms, and emotional function; p < 0.001 for all). The MiA group showed higher scores for all of the PAQLQ components than did the MoA and SA groups. CONCLUSIONS: Quality of life appears to be directly related to asthma control and asthma severity in children and adolescents, being better when asthma is well controlled and asthma severity is lower.

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Section: Discussionmentioning

confidence: 92%

Evaluation of quality of life according to asthma control and asthma severity in children and adolescents

et al. 2015

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“…5 The 6MWT is safe, well understood, and well tolerated in healthy children and in those with various diseases, such as cardiorespiratory 6,7,8 or neuromuscular disorders. 9,10 Due to the high relevance of the 6MWT, some countries have already established reference values for the maximum walk distance for healthy children, such as China, 11 United Kingdom, 12 Thailand, 13 Turkey, 14 India, 15 and the United States of America. 16 Despite this, Brazil, a country with large climatic, socioeconomic, and cultural differences, does not have representative reference values for healthy children.…”

Section: Introductionmentioning

confidence: 99%

Reference Values for the 6-min Walk Distance in Healthy Children Age 7 to 12 Years in Brazil: Main Results of the TC6minBrasil Multi-Center Study

Cacau

Carvalho

et al. 2017

Respir Care

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“…In health children, the 6MWT has been proposed to be a reliable and valid functional test for assessing exercise tolerance [7] . Up to the present moment the literature brings the use of the 6MWT in children/adolescents with, congenital heart disease [6] , severe cardiac impairment (pre cardiac transplantation or pulmonary) [8] , cardiovascular disease, atherosclerosis, hypertension, and obesity in youth [9] , asthma [10] , cystic fibrosis [11] , end-stage renal disease [12] and pulmonary hypertension [13] .…”

Section: Introductionmentioning

confidence: 99%

Reference Values for the Six-Minute Walk Test in Healthy Children and Adolescents: a Systematic Review

Cacau¹,

Santana‐Filho²,

Maynard³

et al. 2016

Brazilian Journal of Cardiovascular Surgery

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ObjectiveThe aim of the study is to compare the available reference values and the six-minute walk test equations in healthy children/adolescents. Our systematic review was planned and performed in accordance with the PRISMA guidelines. We included all studies that established reference values for the six-minute walk test in healthy children/adolescents.MethodsTo perform this review, a research was performed in PubMed, EMBASE (via SCOPUS) and Cochrane (LILACS), Bibliographic Index Spanish in Health Sciences, Organization Collection Pan-American Health Organization, Publications of the World Health Organization and Scientific Electronic Library Online (SciELO) via Virtual Health Library until June 2015 without language restriction.ResultsThe initial research identified 276 abstracts. Twelve studies met the inclusion criteria and were fully reviewed and approved by both reviewers. None of the selected studies presented sample size calculation. Most of the studies recruited children and adolescents from school. Six studies reported the use of random samples. Most studies used a corridor of 30 meters. All studies followed the American Thoracic Society guidelines to perform the six-minute walk test. The walked distance ranged 159 meters among the studies. Of the 12 included studies, 7 (58%) reported descriptive data and 6 (50%) established reference equation for the walked distance in the six-minute walk test.ConclusionThe reference value for the six-minute walk test in children and adolescents ranged substantially from studies in different countries. A reference equation was not provided in all studies, but the ones available took into account well established variables in the context of exercise performance, such as height, heart rate, age and weight. Countries that did not established reference values for the six-minute walk test should be encouraged to do because it would help their clinicians and researchers have a more precise interpretation of the test.

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Comparison of six-minute walk test in children with moderate/severe asthma with reference values for healthy children

Abstract: asthmatic children's performance in the 6MWT evaluated through distance walked is significantly lower than the predicted values for healthy children of the same age, and is directly influenced by sedentary life style.

Cited by 35 publications

References 26 publications

Evaluation of quality of life according to asthma control and asthma severity in children and adolescents

Evaluation of quality of life according to asthma control and asthma severity in children and adolescents

Reference Values for the 6-min Walk Distance in Healthy Children Age 7 to 12 Years in Brazil: Main Results of the TC6minBrasil Multi-Center Study

Reference Values for the Six-Minute Walk Test in Healthy Children and Adolescents: a Systematic Review

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