Milk from Brazilian women presents secretory IgA antibodies and neutralizes rotavirus G9P[5]

Santos, Simone M.R.; Ferreira, Thalita L.; Quintal, Virgínia Spinola; Carbonare, S B; Tino-De-Franco, Milene

doi:10.1016/j.jped.2013.02.017

Cited by 9 publications

(2 citation statements)

References 13 publications

(27 reference statements)

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“…Another study in Brazil on human breast milk has shown the presence of secretory IgA antibodies and rotavirus G9P(5) neutralizing capacity. A strong correlation is seen between the level of anti-rotavirus antibody and the neutralizing capacity of breast milk samples, supporting the possible role of this antibody in protecting against infection [ 24 ].…”

Section: Discussionmentioning

confidence: 93%

Association between Severe Dehydration in Rotavirus Diarrhea and Exclusive Breastfeeding among Infants at Dr. Hasan Sadikin General Hospital, Bandung, Indonesia

Prasetyo

Sabaroedin

Ermaya

et al. 2015

Journal of Tropical Medicine

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Background. Rotavirus is the leading cause of severe acute diarrhea in children. Infants who are exclusively breastfed develop fewer infections and have less severe illnesses. This study aimed to determine association between severe dehydration in rotavirus diarrhea and exclusive breastfeeding. Methods. This is a cross-sectional study in infants ≤ 6 months old with acute diarrhea in Dr. Hasan Sadikin Hospital, Bandung, Indonesia. Results. From 134 infants ≤ 6 months old with acute diarrhea enrolled from April 2009 to December 2012, there were 88 (65.6%) boys and 46 (34.4%) girls in this study. Rotavirus was detected in 60 (44.8 %), 32 (53.3%) of whom were exclusively breastfed. From rotavirus positive subjects, severe dehydration occurred in 4 (12.6%) exclusively breastfed infants and 6 (21.5%) not exclusively breastfed infants. No significant association was found between severe dehydration and exclusive breastfeeding (p = 0.491) in rotavirus diarrhea. Conclusions. In rotavirus diarrhea, there was no significant association between exclusive breastfeeding and severe dehydration.

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Section: Discussionmentioning

confidence: 93%

Association between Severe Dehydration in Rotavirus Diarrhea and Exclusive Breastfeeding among Infants at Dr. Hasan Sadikin General Hospital, Bandung, Indonesia

Prasetyo

Sabaroedin

Ermaya

et al. 2015

Journal of Tropical Medicine

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“…Seasonality of RV in our study was similar to that of other countries with temperate climate, where RV peak is observed in cold seasons; however in countries with tropical or subtropical climates, the virus circulates year-round ( 39 - 41 ). Breast feeding has appeared to have a protective action against rotavirus infection ( 42 , 43 ). The rate of infection in infants who nourish through breast feeding is low, because maternal antibodies that are the result of previous infections are transmitted with breast milk and protect newborns against serious rotavirus infections ( 38 , 42 ).…”

Section: Discussionmentioning

confidence: 99%

Study on Rotavirus Infection and Its Genotyping in Children Below 5 Years in South West Iran

et al. 2016

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BackgroundHuman rotaviruses are the most important agents for severe dehydrating diarrhea in children below 5 years old. Rotaviruses (RV) is a serious public health problem in developing and developed countries.ObjectivesThe aim of this study was to determine the prevalence of rotavirus infection and their genotypes in children younger than 5 years of age with acute diarrhea in Ahvaz, Iran.Materials and MethodsFor this study, 200 stool samples from children below 5 years of age with acute diarrhea were collected between October 2011 and March 2012. Initially all stool samples were tested for rotavirus antigen by ELISA, and positive samples were confirmed by RT-PCR targeting the VP6 rotavirus gene. Determination of rotavirus genotypes was carried out by performing RT-PCR for G and P types. Altogether, 15 samples were sequenced.ResultsOut of 200 stool samples, 100 (50%) had rotavirus antigen detected by ELISA and 73 (36.5%) were found positive by RT-PCR. Of the rotavirus strains identified, only 63 (86.3%) were positive for both VP7 and VP4 while 10 (13.7%) strains were found nontypeable. Rotavirus infection accounts for 36.5% of gastroenteritis cases in samples from symptomatic children. The most prevalent rotavirus genotypes were G1P [8] (80%) followed by G2P [4] (20%).ConclusionsOur results suggest that group A rotavirus is a major pathogene of acute diarrhea in Ahvaz city. The genotypes circulating are similar with those of other countries.

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Milk at altitude: Human milk macronutrient composition in a high‐altitude adapted population of tibetans

Quinn

Bista

Childs

2015

American J Phys Anthropol

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Milk from Brazilian women presents secretory IgA antibodies and neutralizes rotavirus G9P[5]

Abstract: The high correlation between anti-rotavirus antibody levels and neutralizing capacity of the milk samples suggests a possible protective role of these antibodies against infection. These results also support the encouragement of the breast-feeding practice.

Cited by 9 publications

References 13 publications

Association between Severe Dehydration in Rotavirus Diarrhea and Exclusive Breastfeeding among Infants at Dr. Hasan Sadikin General Hospital, Bandung, Indonesia

Association between Severe Dehydration in Rotavirus Diarrhea and Exclusive Breastfeeding among Infants at Dr. Hasan Sadikin General Hospital, Bandung, Indonesia

Study on Rotavirus Infection and Its Genotyping in Children Below 5 Years in South West Iran

Milk at altitude: Human milk macronutrient composition in a high‐altitude adapted population of tibetans

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