The relationship between red cell distribution width and prognostic scores in myelodysplastic syndrome

Turgutkaya, Atakan; Akın, Nesim; Sargın, Gökhan; Bolaman, Zahit

doi:10.1016/j.htct.2020.11.007

Cited by 6 publications

(1 citation statement)

References 17 publications

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“…Thereupon, the percentage changes in RDW values were compared based on hematological response status and survival status, and no significant relationship was identified between RDW changes and hematological response statuses (p=0.375), while these values significantly differed based on survival status (p=0.006) [10]. Furthermore, in a similar study, it was reported that RDW has a potential as a prognostic marker in MDS patients [15]. For these reasons, while the RDW value could not be associated with response to treatment in this study, it was found to be significantly associated with mortality.…”

Section: Original Articlementioning

confidence: 93%

The effects of mean platelet volume and red cell distribution width on prognosis in patients with myelodysplastic syndrome

AYHAN

Ertop

2023

Marmara Medical Journal

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Objective: In this study, the relationship between changes in mean platelet volume (MPV) and erythrocyte distribution width (RDW) with hematological response and survival in patients with myelodysplastic syndrome was investigated. Patients and Methods: Between 1 January 2011 and 31 December 2018, patient characteristics and hemogram results were evaluated during the treatment process among 158 patients diagnosed with myelodysplastic syndrome. Results: The mean age of the patients who were included in the study was 71.53±12.6 years. The MPV percentage change in the 2-year follow-up of the patients with and without hematological response was significant, at 0.022±0.11 (2.2%) in those who responded and at 0.069±0.15 (6.9%) in those who did not (p=0.049). Throughout the same period, the degree of RDW changes in the patients who died was 13.23±22.97, the degree in those who survived was 2.86±21.42, and the difference between the two groups was statistically significant (p=0.006). Conclusion: In patients diagnosed with myelodysplastic syndrome, MPV and RDW values can be considered inexpensive and simple laboratory markers that can be used in follow-ups and promising tests to predict both treatment response and survival in the early period and change treatment modalities.

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Section: Original Articlementioning

confidence: 93%

The effects of mean platelet volume and red cell distribution width on prognosis in patients with myelodysplastic syndrome

AYHAN

Ertop

2023

Marmara Medical Journal

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Improving the diagnosis of myelodysplastic syndrome by red blood cell parameters

et al. 2023

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Serum Erythropoietin level in anemia of elderly with unclear etiology

Seong,

Shin,

Byun

et al. 2023

Sci Rep

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Anemia is a common condition, but its causes are often unclear, especially in elderly adults. Erythropoietin (EPO) levels are known to be elevated in myelodysplastic syndrome and hematologic malignancies, but decreased in chronic benign anemia. This study aimed to investigate whether EPO levels could be used to identify underlying bone marrow diseases including malignancies, among elderly anemic patients with unclear etiology. This single centered retrospective study included patients presented with isolated anemia and had their EPO levels measured at their first visit. Patients were divided into two groups: bone marrow disease and benign etiologic anemia, based on observation and bone marrow test results. Out of 1180 patients reviewed, 81 patients with anemia of unclear etiology were identified, including 67 with benign anemia and 14 with bone marrow disease. Statistically significant difference in EPO levels between these two groups (P < 0.001) were observed. The receiver operating characteristic curve analysis showed that an EPO cut-off value of 36.4 mU/mL had a sensitivity and specificity of 92.8% and 94.0% for detecting underlying bone marrow disease, respectively. We suggest measuring serum EPO levels can aid in the early detection of benign anemia from bone marrow disease, including malignancies, with high sensitivity and specificity.

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The relationship between red cell distribution width and prognostic scores in myelodysplastic syndrome

Cited by 6 publications

References 17 publications

The effects of mean platelet volume and red cell distribution width on prognosis in patients with myelodysplastic syndrome

The effects of mean platelet volume and red cell distribution width on prognosis in patients with myelodysplastic syndrome

Improving the diagnosis of myelodysplastic syndrome by red blood cell parameters

Serum Erythropoietin level in anemia of elderly with unclear etiology

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