Predictors of mortality among patients with acute leukemias admitted to an intensive care unit specialized in patients with hematological disease at a Brazilian hospital

Corrêa, Lorena Costa; Teles, Dahra; Silva, Odin Barbosa da; Trindade-Filho, Gustavo Henriques; Loureiro, Paula; Cavalcati, Maria do Socorro Mendonça

doi:10.1016/j.htct.2019.01.004

Cited by 3 publications

(4 citation statements)

References 19 publications

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“…The characteristics of the 46 included studies are described in eTable 1 (http://links.lww.com/CCX/B54). Most of the published literature was from Europe ( n = 18) (15–32), followed by Asia ( n = 12) (33–44), North America ( n = 9) (4, 45–52), South America ( n = 5) (5, 53–56), and Oceania ( n = 2) (57, 58). On the other hand, studies from North America contributed the highest number of patients ( n = 37,255), followed by South America ( n = 32,723), Asia ( n = 23,540), Europe ( n = 16,149), and Oceania ( n = 478).…”

Section: Resultsmentioning

confidence: 99%

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A Systematic Review and Meta-Analysis Evaluating Geographical Variation in Outcomes of Cancer Patients Treated in ICUs

Nazer

López-Olivo

Brown

et al. 2022

Critical Care Explorations

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Section: Resultsmentioning

confidence: 99%

“…Ten studies did not report hospital mortality data (18, 22, 32, 34, 35, 37, 38, 41, 46, 53). The risks of selection, attrition, outcome, and missing data biases were considered low for the 36 studies reporting on hospital mortality.…”

Section: Resultsmentioning

confidence: 99%

A Systematic Review and Meta-Analysis Evaluating Geographical Variation in Outcomes of Cancer Patients Treated in ICUs

Nazer

López-Olivo

Brown

et al. 2022

Critical Care Explorations

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“…Depuydt et al appealed to IMV for HM with ARF who were excluded from NIV, especially for those whose admission to ICU was driven by sepsis [44]. Other risk factors of NIV failure were also reported in different investigations, which included need for vasopressor, longer delay between admission and NIV, acute respiratory distress syndrome (ARDS), hepatic failure, hemodialysis, high APACHE II and SAPS II score, et al [4,35,37,39,41,45,[54][55][56].…”

Section: Imv For Hm With Arfmentioning

confidence: 99%

Management strategy for hematological malignancy patients with acute respiratory failure

Jiang

Wan

2021

Eur J Med Res

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Acute respiratory failure (ARF) is still the major cause of intensive care unit (ICU) admission for hematological malignancy (HM) patients although the advance in hematology and supportive care has greatly improved the prognosis. Clinicians have to make decisions whether the HM patients with ARF should be sent to ICU and which ventilation support should be administered. Based on the reported investigations related to management of HM patients with ARF, we propose a selection procedure to manage this population and recommend hematological ICU as the optimal setting to recuse these patients, where hematologists and intensivists can collaborate closely and improve the outcomes. Moreover, noninvasive ventilation (NIV) still has its own place for selected HM patients with ARF who have mild hypoxemia and reversible causes. It is also crucial to monitor the efficacy of NIV closely and switch to invasive mechanical ventilation at appropriate timing when NIV shows no apparent improvement. Otherwise, early IMV should be initiated to HM with ARF who have moderate and severe hypoxemia, adult respiratory distress syndrome, multiple organ dysfunction, and unstable hemodynamic. More studies are needed to elucidate the predictors of ICU mortality and ventilatory mode for HM patients with ARF.

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“…1, нами была выявлена достоверно значимая разница в длительности респираторной поддержки в группе пациентов с ОМЛ. Известно, что длительность респираторной поддержи, является неблагоприятным предиктором летального исхода при пневмонии, а также потребность в НИВЛ чаще имеют пациенты с миелобластным вариантом ОЛ [9,10,14].…”

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Features of the clinical course of severe community-acquired pneumonia caused by Klebsiella pneumoniae in patients with acute leukemia

Saharov

Миронов

Lutfarakhmanov

et al. 2023

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Aim: To compare the course of severe community-acquired pneumonia caused by Kl. pneumonia in patients with acute lymphoblastic and myeloblastic leukaemia.Materials and methods. The study was designed as a retrospective, single-centre, controlled and non-randomized study and included 40 patients. They were divided into two groups: patients with acute myeloblastic leukaemia (22), mortality of 59% (13 patients) and patients with acute lymphoblastic leukaemia (18), mortality of 38% (7 patients).Results and discussion. The combination of acute myeloblastic leukaemia and severe community-acquired pneumonia caused by Kl. pneumonia showed a higher mortality rate, a longer duration of respiratory support, as well as a greater frequency of involvement of organs and systems in the infectious process than in acute lymphoblastic leukaemia.Conclusions: The development of pneumonia caused by Kl. pneumonia in patients with acute myeloblastic leukaemia is characterized by a more severe course. SOFA, APACHE-II, and PSI/PORT scales have limited predictive ability in patients with acute leukaemia and severe community-acquired pneumonia caused by Kl. Pneumoniae.

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Predictors of mortality among patients with acute leukemias admitted to an intensive care unit specialized in patients with hematological disease at a Brazilian hospital

Cited by 3 publications

References 19 publications

A Systematic Review and Meta-Analysis Evaluating Geographical Variation in Outcomes of Cancer Patients Treated in ICUs

A Systematic Review and Meta-Analysis Evaluating Geographical Variation in Outcomes of Cancer Patients Treated in ICUs

Management strategy for hematological malignancy patients with acute respiratory failure

Features of the clinical course of severe community-acquired pneumonia caused by Klebsiella pneumoniae in patients with acute leukemia

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