Effects of anthraquinone extract from Rheum officinale Bail on the physiological responses and HSP70 gene expression of Megalobrama amblycephala under Aeromonas hydrophila infection

Liu, Bo; Ge, Xianping; Xie, Jun; Xu, Pao; He, Yanan; Cui, Yanting; Ming, Jianhua; Zhou, Qunlan; Pan, Liangkun

doi:10.1016/j.fsi.2011.02.015

Cited by 95 publications

(42 citation statements)

References 58 publications

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“…Activities of acidic phosphatase (ACP), alkaline phosphatase (AKP), catalase (CAT) and superoxide dismutase (SOD) in hepatic (liver), muscular (muscle), branchial (gills) and renal (kidney) tissues and plasma cortisol levels were monitored as biomarkers of salinity stress. This research was intended to identify the key ecological factors whose variations might threaten the growth and Pickering & Pottinger (1995) modified by Liu et al (2012).…”

Section: Experimental Designmentioning

confidence: 99%

Effects of the amplitude and frequency of salinity fluctuations on antioxidant responses in juvenile tongue sole, Cynoglossus semilaevis

Khairnar¹,

Tian²,

Dong³

et al. 2016

Span J Agric Res

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Baysoy et al., 2012;Ern et al., 2014;Khairnar et al., 2015;Wedderburn et al., 2016), which has been associated with enhanced reactive oxygen species (ROS) generation (Livingstone, 2001). In order to counteract the potential damage resulting from excess reactive oxygen and to maintain its homeostasis, living organisms have evolved a delicate antioxidant mechanism consisting mainly of two systems: the enzyme system and the non-enzyme system. In biological research, RESEARCH ARTICLE OPEN ACCESS AbstractTo understand the tolerance of tongue sole, Cynoglossus semilaevis, to varying salinities, the effects of the amplitude (2, 4, 6 and 8 g/L) and frequency (2, 4 and 8 days) of salinity fluctuations on the activities of antioxidant responses, including acidic phosphatase (ACP), alkaline phosphatase (AKP), catalase (CAT) and superoxide dismutase (SOD) from antioxidant system in liver, muscle, gills and kidney were investigated in this study. The results showed that the antioxidant responses of tongue sole were highly tissue-specific during the varying salinity fluctuations. In all tissues, ACP and AKP activity was found to be highest at moderate salinity fluctuations compared to the control, low and high salinity treatments (p<0.05). SOD and CAT activities had significant effect due to salinity fluctuations in all tissues (p<0.05), except in hepatic and renal tissues. Variations in branchial SOD activity proved that salinity fluctuations had greater impact on tongue sole at moderate and high fluctuating salinities compared to the control and low fluctuating salinities, whereas the branchial CAT activities showed contrasting trend. Further, cortisol levels were significantly affected in lower and higher salinity fluctuations. However, plasma cortisol levels remained low in moderate salinity fluctuations and control (p<0.05). Taken together, the results indicated that salinity fluctuations could effectively stimulate and enhance the antioxidant enzyme activity in the liver, kidney, gills and muscle of the juvenile tongue sole, thus effectively eliminating the excessive reactive oxygen species and minimizing the body damage in tongue sole or could be for any other euryhaline teleosts.Additional key words: salinity variation; enzyme activity; immunomarker; environmental stress; aquaculture.

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Section: Experimental Designmentioning

confidence: 99%

Effects of the amplitude and frequency of salinity fluctuations on antioxidant responses in juvenile tongue sole, Cynoglossus semilaevis

Khairnar¹,

Tian²,

Dong³

et al. 2016

Span J Agric Res

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“…Earlier studies in our laboratory found that serum concentrations of cortisol significantly increased under high temperature and pathogenic infection in Wuchang bream (Liu et al 2010;Liu et al 2012) and high dose of 700 mg/kg vit C reduced the serum cortisol concentrations . In the present study, serum cortisol concentrations were significantly reduced in the treatment groups of 251.5 mg/kg vit C after pH stress compared with the control group.…”

Section: Discussionmentioning

confidence: 57%

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Liu¹,

Wan²,

Ge³

et al. 2016

Turk. J. Fish. Aquat. Sci.

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We evaluated the effect of vitamin C (Vit C) supplementation on the resistance of Megalobrama amblycephala to Aeromonas hydrophi1a infection under pH stress. Fish were randomly divided into six groups: a control group (fed with a basal diet) and five treatment groups (fed with basal diet supplemented with 33.4, 65.8, 133.7, 251.5 and 501.5 mg/kg Vit C, respectively). After 90 days, fish were exposed to combined stressors, first pH 9.5 followed by A. hydrophila infection. The results showed that 133.7 mg/kg vit C improved complement 4 (C4), anti-superoxide anion free aradical (ASAFER) and heat shock protein (HSP) 70 compared with the control group; and 251.5 mg/kg vit C enhanced complement 3 (C3), HSP60, HSP70 and HSP90 compared to the control group before stress. After pH stress and A. hydrophila infection, hemoglobin, ASAFER and HSP60, HSP70, HSP90 in the groups fed with 133.7 and 251.5 mg/kg vit C were still significantly higher, while serum cortisol in the group fed with 251.5 mg/kg vit C was lower compared to the control group 15 days after pH stress. The cumulative mortality of the control group was higher than that of the five treatment groups at 12, 24 h after A. hydrophila infection. The results of this study suggest that 133.7-251.5mg/kg vit C in a diet could have potential to stimulate immune response, and enhance resistance against high pH stress and A. hydrophila infection of Wuchang bream.

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“…This result suggests that EO and the SBA-15|EO after oral administration have different bioavailability, absorptive, and/or metabolic behaviors in the digestive tract or whole insect body. Pharmacokinetic studies in rat and human intestinal epithelium models revealed that EO, similarly to other dietary polyphenols, has low bioavailability in vivo because of poor intestinal absorption (Teng et al, 2012;Dong et al, 2016) and rapid elimination via extensive glucuronidation (Liu B et al, 2012;Wu et al, 2014). It was shown that the bioavailability of EO is dependent on both the number of free hydroxyl and methyl groups, because the methyl groups of EO can hamper the production of sulfated metabolites and increase the possibility of interaction between the hydroxyl groups and glucuronidation enzymes (Teng et al, 2012).…”

Section: Discussionmentioning

confidence: 99%

Mesoporous silica nanoparticles SBA-15 loaded with emodin upregulate the antioxidative defense of Euproctis chrysorrhoea (L.) larvae

et al. 2017

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The study presented here aims to elucidate the effects of emodin (EO = 1,3,8-trihydroxy-6-methylanthraquinone) in its free form and when loaded into a mesoporous silica nanocarrier SBA-15 (→ SBA-15|EO) on the activities of the main antioxidative enzymes, superoxide dismutase, catalase, glutathione S-transferase, and glutathione reductase, in larvae of a polyphagous insect pest, the browntail moth Euproctis chrysorrhoea (L.). The results show that only SBA-15|EO upregulates the activities of the tested antioxidative enzymes. These results point to significant differences in the effectiveness of the compound in the free versus the loaded form.

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Effects of anthraquinone extract from Rheum officinale Bail on the physiological responses and HSP70 gene expression of Megalobrama amblycephala under Aeromonas hydrophila infection

Cited by 95 publications

References 58 publications

Effects of the amplitude and frequency of salinity fluctuations on antioxidant responses in juvenile tongue sole, Cynoglossus semilaevis

Effects of the amplitude and frequency of salinity fluctuations on antioxidant responses in juvenile tongue sole, Cynoglossus semilaevis

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Mesoporous silica nanoparticles SBA-15 loaded with emodin upregulate the antioxidative defense of Euproctis chrysorrhoea (L.) larvae

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