Characteristics of the oral glucose tolerance test in women with different pre-pregnancy body mass index and the effect of gestational diabetes mellitus on twin pregnancy outcomes

Luo, Jinying; Geng, Xiaoyan; Zhou, Jinfu; Liang, Shengnan; Zheng, Wei; Li, Guanghui

doi:10.1016/j.clinsp.2023.100272

Cited by 1 publication

(1 citation statement)

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“…Pregnant women at the gestational age of 24 to 28 wk, underwent an oral glucose tolerance test. Glucose water (75 g) was consumed after 8 h fasting on an empty stomach and then blood glucose was measured 3 times within 2 h. A diagnosis of GDM was made if the blood glucose level measured ≥ 5.1 mmol/L, 10.0 mmol/L, or 8.5 mmol/L during the fasting, 1-h, or 2-h tests, respectively[ 6 ].…”

Section: Methodsmentioning

confidence: 99%

Establishment and evaluation of a risk prediction model for gestational diabetes mellitus

Lin,

Fang

2023

World J Diabetes

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Diabetes mellitus is one of the most common causes of chronic kidney disease. Kidney involvement in patients with diabetes has a wide spectrum of clinical presentations ranging from asymptomatic to overt proteinuria and kidney failure. The development of kidney disease in diabetes is associated with structural changes in multiple kidney compartments, such as the vascular system and glomeruli. Glomerular alterations include thickening of the glomerular basement membrane, loss of podocytes, and segmental mesangiolysis, which may lead to microaneurysms and the development of pathognomonic Kimmelstiel-Wilson nodules. Beyond lesions directly related to diabetes, awareness of the possible coexistence of nondiabetic kidney disease in patients with diabetes is increasing. These nondiabetic lesions include focal segmental glomerulosclerosis, IgA nephropathy, and other primary or secondary renal disorders. Differential diagnosis of these conditions is crucial in guiding clinical management and therapeutic approaches. However, the relationship between diabetes and the kidney is bidirectional; thus, new-onset diabetes may also occur as a complication of the treatment in patients with renal diseases. Here, we review the complex and multifaceted correlation between diabetes and kidney diseases and discuss clinical presentation and course, differential diagnosis, and therapeutic oppor-tunities offered by novel drugs.

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Section: Methodsmentioning

confidence: 99%