Comparative effects of fractional radiofrequency and microneedling on the genitalia of postmenopausal women: Histological and clinical changes

Maia, Rafaella Rêgo; Sarmento, Ayane Cristine Alves; Silva, Rodrigo Marcel Valentim da; Carreiro, Eneida de Morais; Farias, Stephany Luanna Queiroga; Soares, Ciro Dantas; Meyer, Patrícia Fróes; Gonçalves, Ana Katherine

doi:10.1016/j.clinsp.2022.100117

Cited by 2 publications

(1 citation statement)

References 33 publications

(30 reference statements)

Supporting

Mentioning

Contrasting

Order By: Relevance

“…RF therapy with a set temperature of 40 ~ 45 °C was reported to be correlated with vaginal elasticity recovery and increased vaginal mucosal moisture, and these actions were attributed to various factors, such as growth factor/collagen production in fibroblast via activating heat-shock proteins and inhibiting inflammatory cascade [ 21 , 37 ]. Moreover, a histological analysis by Maia RR et al showed fractional RF improved the number of fibroblasts, blood vessels, and fatty degeneration with higher type III collagen and vimentin expression [ 38 ]. Therefore, RF improved nerve sensitivity, vaginal vascularization, collagen fiber reorganization, thus contributing to a decrease in the sensation of vaginal laxity and an increased in sexual function, including arousal and orgasmic dysfunction [ 39 , 40 ].…”

Section: Discussionmentioning

confidence: 99%

The efficacy and safety of temperature controlled dual-mode radiofrequency in women with vaginal laxity

Long

Qin

et al. 2023

BMC Women's Health

View full text Add to dashboard Cite

Objective Vaginal laxity could negatively influence women’s sexual function. This study aimed to explore the efficacy and safety of temperature controlled dual-mode (monopolar and bipolar) radiofrequency (RF) in women with vaginal laxity. Methods A total of 102 patients with vaginal laxity were treated with temperature-controlled RF. The present study implemented Vaginal Laxity Questionnaire (VLQ), Female Sexual Function Index (FSFI) questionnaire and Sexual Satisfaction Questionnaire (SSQ) on all patients at baseline and after treatment. Pelvic Organ Prolapse Quantification System (POP-Q) system was applied to physical examination, and vaginal manometer to examine the strength of voluntary contractions of the pelvic floor muscles. Results The VLQ score was gradually increased after RF treatment at 1, 3, 6 and 12 months, accompanying by the significant improvement in total FSFI scores and the six domains (sexual desire, sexual arousal, lubrication, orgasm, satisfaction, pain). The increased sexual satisfaction based on the SSQ score was found after temperature-controlled RF. The result of POP-Q stage showed significant difference in women after treatment, with the women having Stage I of 45.10% at baseline, 36.27% at 1 month, 28.43% at 3 months, 19.61% at 6 months and 10.78% at 12 months. The mean pressure and mean duration of pelvic contractions were increased gradually at the 1-, 3-, 6- and 12- month follow-up. Conclusion Temperature controlled dual-mode (monopolar and bipolar) radiofrequency may be associated with improvement of vaginal laxity, and contribute to enhancement to female sexual function and pelvic floor muscles.

show abstract

Section: Discussionmentioning

confidence: 99%

The efficacy and safety of temperature controlled dual-mode radiofrequency in women with vaginal laxity

Long

Qin

et al. 2023

BMC Women's Health

View full text Add to dashboard Cite

show abstract

Changes in vaginal secretion lipidom as a result of therapy in patients with vulvovaginal atrophy

Kazakova,

Tokareva,

Novoselova

et al. 2024

Medicinskij sovet

View full text Add to dashboard Cite

Introduction. Vulvovaginal atrophy is a chronic progressive disease that includes physiological and anatomical changes as a result of a decrease in the level of sex hormones. VVA affects approximately 50% of middle-aged and older women and has a detrimental effect on interpersonal relationships, sexual health, and overall quality of life. Dynamic quadripolar radiofrequency (DRF) is a non-invasive procedure that may be a potential treatment for vulvar diseases.Aim. To study the metabolites of vaginal swabs in postmenopausal women treated with DRF.Materials and methods. The study included 180 women divided into 3 groups: treatment with DRF; treatment with a combination of DRF and estradiol, and estradiol treatment. In all patients, vaginal swabs were taken before the start of treatment and a month after treatment, and clinical parameters were assessed at 6 time points. Lipids were extracted from the cervico-vaginal fluid by the Folch method followed by liquid chromatography-mass spectrometric analysis. A comparative analysis of the clinical data of each of the groups and lipid profiles after treatment with a zero time point and their changes and a correlation analysis of changes in lipid levels and changes in clinical parameters before treatment and after 1 month was carried out.Results. There was a statistically significant reduction in the severity of VVA symptoms one month after treatment in all groups. The most pronounced effect of the therapy was observed in groups with the use of DRF with the preservation of the effect up to 12 months. In the first and second groups, a statistically significant difference was found in the levels of 2 lipids, in the third – in 4. In the first group, a correlation was found with lipids related with pain and lubrication, in the second – with vaginal pH, in the third – with the index of vaginal health, orgasm, satisfaction and pain.Conclusions. VVA therapy by DRF and local hormonal treatment triggers an inflammatory cascade in tissues. The use of the strategy of treatment with physical methods of influence has a mechanism of influence similar to the local application of estrogen in VVA. DRF therapy leads to the normalization of the vaginal microbiota and can compete with the use of estrogen in this therapeutic effect.

show abstract

Comparative effects of fractional radiofrequency and microneedling on the genitalia of postmenopausal women: Histological and clinical changes

Cited by 2 publications

References 33 publications

The efficacy and safety of temperature controlled dual-mode radiofrequency in women with vaginal laxity

The efficacy and safety of temperature controlled dual-mode radiofrequency in women with vaginal laxity

Changes in vaginal secretion lipidom as a result of therapy in patients with vulvovaginal atrophy

Contact Info

Product

Resources

About