Liver transplant after SARS-CoV-2 infection: A systematic review

Nacif, Lucas Souto; Fernandes, Michel Ribeiro; Waisberg, Daniel Reis; Pinheiro, Rafael Soares; Rocha-Santos, Vinícius; Galvão, Flávio Henrique Ferreira; Andraus, Wellington; D’Albuquerque, Luiz Augusto Carneiro

doi:10.1016/j.clinsp.2022.100042

Cited by 4 publications

(2 citation statements)

References 33 publications

(38 reference statements)

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“…One recent review studied liver transplant outcomes in patients with high MELD or fulminant hepatitis diagnosed with COVID-19 just prior to transplant (median 19 days before initiation), and found no increase in mortality compared to normal transplant patients. 47 Routine screening for COVID-19 is recommended in both donors and recipients. Although transplant is contraindicated in the setting of active infection, patients can be considered for liver transplantation 14–21 days after the initial infection, particularly if repeat testing is negative.…”

Section: Liver Transplantation and Covid-19mentioning

confidence: 99%

“… 48 Mycophenolate mofetil, on the other hand, is an independent predictor of severe COVID-19 in liver transplant recipients. 47 As such, optimal management regarding immunosuppression in the setting of COVID-19 is unclear. Reducing the overall level of immunosuppression is reasonable in post-transplant recipients with COVID-19 infection.…”

Section: Liver Transplantation and Covid-19mentioning

confidence: 99%

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COVID-19-Associated Liver Injury

Gildea¹,

Woo²,

O'Connor³

et al. 2023

HMER

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This review analyzes data regarding liver injury associated with COVID-19 infection. We discuss reported effects on the liver from both COVID-19 and COVID-19 treatment as well as pathophysiology, review the potential role of drug-induced liver injury as an etiology of COVID-19-associated liver injury, and touch on other reports of significant outcomes including COVID-19 cholangiopathy and autoimmune hepatitis. Finally, we review the implications of COVID-19 infection in liver transplant recipients.

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Section: Liver Transplantation and Covid-19mentioning

confidence: 99%

Section: Liver Transplantation and Covid-19mentioning

confidence: 99%