Epidemiology of adult atopic dermatitis

Sacotte, R.; Silverberg, Jonathan I.

doi:10.1016/j.clindermatol.2018.05.007

Cited by 133 publications

(97 citation statements)

References 128 publications

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“…This proportion, consistent with previous studies, 26‐29 may indicate that women were more often affected by contact dermatitis than men. There is a clinical notion that women are more skin‐reactive than men, and it has been observed that AD shows a female preponderance in adulthood, 26,30 the latter perhaps related to an exacerbation of Th2 inflammation supported by estradiol and other female sex hormones 31 . Moreover, female skin is thinner due to lower testosterone levels, 32,33 and there is a lower epidermal cellular density, and lower collagen content in female skin at all ages, compared with men 34,35 .…”

Section: Discussionmentioning

confidence: 99%

Occupational contact dermatitis in Triveneto: Analysis of patch test data of the North Eastern Italian Database from 1996 to 2016

et al. 2020

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Background: Occupational contact dermatitis (OCD) is frequent in the workplace.Objectives: To provide recent data on the epidemiology of OCD in Italy.Methods: This multicenter retrospective study, conducted from 1996 to 2016, included patients with suspected allergic contact dermatitis (ACD) patch tested in the departments comprising the North-East Italy Contact Dermatitis Group.Results: We studied 18 859 workers with a diagnosis of contact dermatitis (CD), of which 10.4% were recognized as being of professional origin. OCD declined from 1996 to 2011-2013 and increased in 2014-2016. The overall prevalence of both CD and OCD was higher in women compared to men, but the share of OCD of the total CD was greater for men compared to women. A history of atopic dermatitis was less frequent in workers with OCD than in non-OCD patients (5.8% vs 8.6%). Hairdressers were the youngest profession (27.1 ± 11.7 years). Hands were the primary site of involvement in patients with OCD (76.6%). The five highest risk occupations for OCD were hairdressers, cooks, metalworkers, chemical industry workers, and construction workers. Conclusions:OCDs have a relevant impact in our region, mainly for five job categories, and the increase in the last 3 years suggests the need to improve preventive measures.

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Section: Discussionmentioning

confidence: 99%

Occupational contact dermatitis in Triveneto: Analysis of patch test data of the North Eastern Italian Database from 1996 to 2016

et al. 2020

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“…Atopic dermatitis (AD) is a chronic inflammatory skin disease evolving through a pattern of flares and remission, which affects 5–20% of children under 11 years old and 1–17% of adults . In sub‐Saharan Africa, AD prevalence in children aged 6–7 years is about 5%, and in children aged 13–14 years is between 8% and 19% …”

Section: Introductionmentioning

confidence: 99%

“…Atopic dermatitis (AD) is a chronic inflammatory skin disease evolving through a pattern of flares and remission, which affects 5-20% of children under 11 years old 1-3 and 1-17% of adults. [4][5][6] In sub-Saharan Africa, AD prevalence in children aged 6-7 years is about 5%, and in children aged [13][14] years is between 8% and 19%. 7,8 The SCORing for AD (SCORAD) index, first described in 1993 by the European Task Force on AD, 9 was developed in order to assess the severity of the disease and improve AD management.…”

Section: Introductionmentioning

confidence: 99%

Validation of the Patient‐Oriented SCORing for Atopic Dermatitis tool for black skin

Faye¹,

N'Djong

Diadié

et al. 2019

Acad Dermatol Venereol

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Background SCORing for Atopic Dermatitis (SCORAD) is a tool developed by the European Task Force on Atopic Dermatitis (AD) which is used by physicians to assess AD severity during consultations with their patients. Patient‐Oriented SCORAD (PO‐SCORAD) is a self‐assessment tool for use by patients which has been validated in a study performed in European countries. However, there is currently no adapted tool for evaluating AD severity in black skin. Objective To evaluate the performance of the version of the PO‐SCORAD specifically adapted for black skin patients (children and adults) with AD. Methods In this multicenter, cross‐sectional and non‐interventional study, children and adults with AD were recruited during regular consultations. This international study was performed in seven sub‐Saharan countries (Benin, Burkina Faso, Cameroon, Ivory Coast, Gabon, Mali and Senegal). During the consultation, AD severity was assessed by the physician using SCORAD score and by the patients or parents using PO‐SCORAD. Results One hundred and thirteen patients were included, 72 children and 41 adults, mainly females (61.6%). SCORAD assessed by physicians and PO‐SCORAD assessed by patients/parents were well correlated (r = 0.66, P < 0.0001). Correlation coefficients for SCORAD and PO‐SCORAD subscale scores were also good, except for symptom intensity criteria. Conclusion Altogether, these data indicate that PO‐SCORAD for black skin correlates well with SCORAD and is therefore a valuable tool, which requires no specific level of education, for use by black skin patients with AD.

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“…A major concern about integromics analysis and sharing of such big medical data is the difficult question regarding privacy and security (120), which needs to be solved before a massive open online medical (MOOM) repository can become a reality (22). Affects 10-25% of all children and 2-10% of the adult population (123), corresponding to at least 320 million people worldwide, 11 and with wide regional variation (125). 85-95% of all cases begin before the age of 5 years (126) Prevalence has more than doubled within the last 50 years (127), which suggests environmental effects, 12 including lifestyle changessuch as 'Westernization' and the hygiene hypothesis (128).…”

Section: Integromicsmentioning

confidence: 99%

Personalized medicine—concepts, technologies, and applications in inflammatory skin diseases

Litman

2019

APMIS

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Epidemiology of adult atopic dermatitis

Cited by 133 publications

References 128 publications

Occupational contact dermatitis in Triveneto: Analysis of patch test data of the North Eastern Italian Database from 1996 to 2016

Occupational contact dermatitis in Triveneto: Analysis of patch test data of the North Eastern Italian Database from 1996 to 2016

Validation of the Patient‐Oriented SCORing for Atopic Dermatitis tool for black skin

Personalized medicine—concepts, technologies, and applications in inflammatory skin diseases

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