Chemical constituents of Cycas vespertilio

Ragasa, Consolacion Y.; Ng, Vincent Antonio S.; Agoo, Esperanza Maribel G.; Shen, Chien‐Chang

doi:10.1016/j.bjp.2015.06.002

Cited by 10 publications

(12 citation statements)

References 8 publications

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“…Identification of lignans 4 and 5 was based on experiments 1 H and 13 C NMR, and HMBC. 1 H and 13 C NMR data are in accordance with those reported in the literature as paulownin 22,23 and cycloolivil 24 , respectively. In this study furanonaphthoquinone 2 and lignans 4 and 5 are being reported for the first time from ipê-amarelo wood.…”

Section: Resultssupporting

confidence: 90%

Antifungal and Antiplasmodial Activity of Isolated Compounds from Handroanthus serratifolius (Vahl) S. Grose Sawdusts

Melo¹,

Cruz²,

Soares³

et al. 2019

IJAERS

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Handroanthus serratifolius (Vahl) S. Grose [Tabebuia serratifolia (Vahl) G. Nicholson] popularly known in Brazil "ipê-amarelo" is a woody species with potential of sustainable use belonging to a genus known for being as a promising naphthoquinones source which has aroused interest in search for new biological activities. In this paper, the methanolic extract fractionation from H. serratifolius sawdust using different chromatogramphic techniques yielded naphthoquinones dehydro-α-lapachone, dehydro-iso-α-lapachone and αlapachone, along with lignans paulownin and cycloolivil. The three naphthoquinones presented antiplasmodial activity against Plasmodium falciparum where the dehydro-iso-α-lapachone was more active (IC50 of 7.53 μg/mL). This same compound also exhibited significant antifungal activity against Cryptococcus neoformans.

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Section: Resultssupporting

confidence: 90%

Antifungal and Antiplasmodial Activity of Isolated Compounds from Handroanthus serratifolius (Vahl) S. Grose Sawdusts

Melo¹,

Cruz²,

Soares³

et al. 2019

IJAERS

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“…Nine lignans; isolated by column chromatography; were reported from certain members of genus Cycas. C. vespertilio 34,42 and C. aenigma 43 have yielded pinoresinol (55). Sesamin (56) was isolated from C. vespertilio 24 and C. sancti-lasallei 44 .…”

Section: Lignansmentioning

confidence: 99%

“…Sesamin (56) was isolated from C. vespertilio 24 and C. sancti-lasallei 44 . Both paulownin (57) 42 and (+)-lariciresinol (57) 34,42 were obtained from C. vespertilio. (+)-lariciresinol (58) was separated from C. revoluta 8 .…”

Section: Lignansmentioning

confidence: 99%

Phytochemical content and biological activity of the genus Cycas, Family Cycadaceae: A review

Afifi¹,

Moawad²,

Hassan³

et al. 2021

Pharm Sci Asia

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Genus Cycas, Cycadaceae family, contains about 117 species. Nevertheless, few species have been phytochemically and pharmacologically studied. To date Eighty-eight secondary metabolites, including flavonoids, terpenoids, lignans, aromatic acids and sterols were isolated and identified from nineteen Cycas species. Among the isolated compounds flavonoids are the most prevalent metabolites. The extracts as well as pure compounds isolated from Cycas species were reported to exhibit a wide range of biological activities including; antimicrobial, anti-oxidant, antidiabetic, cytotoxic, anthelmintic, analgesic, anti-arthritic, anti-inflammatory and thrombolytic activities. The present review highlights the reported phytochemical content as well as the pharmacological potential of Cycas species. Interestingly, it indicates that; almost all the previous investigation of the biological activity of pure compounds isolated from this genus was directed towards its flavonoid content. Accordingly, more biological studies are needed to figure out the possible role of other isolated compounds in the observed biological activities and/or the reported traditional uses of different Cycas species. Moreover, further studies are required to investigate other unexplored species.

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“…AHCs have been reported in more than 50 plant species and are likely even more widespread in the plant kingdom. Given that AHCs have been found in extant cycads like Cycas vespertilio [ 3 ] and many other gymnosperms [ 2 ], it can be hypothesized that their biosynthesis originated with, if not before, the appearance of gymnosperms. However, since fatty alcohols and hydroxycinnamates have been found in the cuticle of extant plants, whose appearance in evolutionary time predates that of gymnosperms (e.g., Physcomitrella patens ) [ 4 ], it is likely that the capacity for plants to synthesize AHCs evolved more than 300 mya.…”

Section: The Occurrence Of Alkyl Hydroxycinnamatesmentioning

confidence: 99%

Occurrence and Biosynthesis of Alkyl Hydroxycinnamates in Plant Lipid Barriers

Domergue

Kosma

2017

Plants

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The plant lipid barriers cuticle and suberin represent one of the largest biological interfaces on the planet. They are comprised of an insoluble polymeric domain with associated organic solvent-soluble waxes. Suberin-associated and plant cuticular waxes contain mixtures of aliphatic components that may include alkyl hydroxycinnamates (AHCs). The canonical alkyl hydroxycinnamates are comprised of phenylpropanoids, typically coumaric, ferulic, or caffeic acids, esterified with long chain to very long chain fatty alcohols. However, many related structures are also present in the plant kingdom. Although their functions remain elusive, much progress has been made on understanding the distribution, biosynthesis, and deposition of AHCs. Herein a summary of the current state of knowledge on plant AHCs is provided.

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Chemical constituents of Cycas vespertilio

Cited by 10 publications

References 8 publications

Antifungal and Antiplasmodial Activity of Isolated Compounds from Handroanthus serratifolius (Vahl) S. Grose Sawdusts

Antifungal and Antiplasmodial Activity of Isolated Compounds from Handroanthus serratifolius (Vahl) S. Grose Sawdusts

Phytochemical content and biological activity of the genus Cycas, Family Cycadaceae: A review

Occurrence and Biosynthesis of Alkyl Hydroxycinnamates in Plant Lipid Barriers

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