UHPLC–MS quantification of coumarin and chlorogenic acid in extracts of the medicinal plants known as guaco (Mikania glomerata and Mikania laevigata)

Melo, Lucília Vilela de; Sawaya, Alexandra Christine Helena Frankland

doi:10.1016/j.bjp.2015.02.005

Cited by 35 publications

(17 citation statements)

References 18 publications

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“…It also reduces blood sugar levels and potentially exerts an anti-diabetic effect [26,27]. Thus, the quantitation of CGA in coffee and in plant materials has merited great interest, and a number of methods have been employed for the measurement of CGA based on chromatography [28][29][30], capillary electrophoresis [31][32][33][34] and voltammetry [35][36][37]. Several voltammetric sensors for CGA have likewise been developed [38][39][40], but no potentiometric sensors have yet been described for this analyte.…”

Section: Introductionmentioning

confidence: 99%

Biomimetic potentiometric sensor for chlorogenic acid based on electrosynthesized polypyrrole

Koirala

Sevilla

Santos

2016

Sensors and Actuators B: Chemical

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Section: Introductionmentioning

confidence: 99%

Biomimetic potentiometric sensor for chlorogenic acid based on electrosynthesized polypyrrole

Koirala

Sevilla

Santos

2016

Sensors and Actuators B: Chemical

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“…Belonging to the same Polygonaceae family, Rheum had p ‐coumaric acid of 9–26 µg/g DW and buckwheat had cinnamic acid of 3.10–3.70 mg/g DW, which were significantly lower than those in polygonum, respectively (Wiczkowski et al, ). Compared with other herb plants, polygonum cuspidatum had higher concentration of coumarin (8.40 ± 0.41 mg/g DW) than guaco (0.775–1.131 mg/g DW) and higher ellagic acid (12.36 ± 0.93 mg/g DW) than geum (0.44–0.57 mg/g DW) (de Melo & Sawaya, ; Owczarek, Olszewska, & Gudej, ).…”

Section: Resultsmentioning

confidence: 99%

Capability of polygonum cuspidatum extract in inhibiting AGEs and preventing diabetes

Sheng

Zheng

et al. 2019

Food Science & Nutrition

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Diabetes is a metabolic disorder disease associated with advanced glycation end products (AGEs) and protein glycation. The effect of polygonum cuspidatum extract (PE) on AGEs and Nε‐(Carboxymethyl)‐L‐lysine formation, protein glycation, and diabetes was investigated. Six primary phenolics in a range of 12.36 mg/g for ellagic acid to 0.01 mg/g for piceid were determined in PE. In an intermediate‐moisture‐foods model, inhibition rate of PE was as high as 54.2% for AGEs and 78.9% for CML under aw 0.75. The protein glycation was also inhibited by PE. In a diabetic rat model, the levels of blood glucose, serum malondialdehyde, cholesterol, triglycerides, and low‐density lipoproteins were effectively reduced by PE treatment. The antioxidation capacity (T‐AOC) and superoxide dismutase (SOD) activity were also mediated by PE. Additionally, the activates of liver function‐related enzymes including alkaline phosphatase (ALP), glutamate pyruvate transaminase (GPT), and glutamate oxaloacetate transaminase (GOT) in diabetic rat were improved by PE.

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“…Herbal medicinal sources of chlorogenic acid are the flowers and buds of Japanese honeysuckle ( Lonicera japonica ) [ 50 , 51 ], South China honeysuckle ( Lonicera confusa ) [ 52 ], leaves of “guaco” ( Mikania glomerata and Mikania laevigata ) [ 53 ], Kuding tea ( Ilex latifolia ) [ 54 ], and zhi zi ( Gardenia jasminoides ) fruits [ 55 ].…”

Section: Biosynthesis and Sources Of Chlorogenic Acidmentioning

confidence: 99%

Chlorogenic Acid and Mental Diseases: From Chemistry to Medicine

Nabavi

Tejada

Setzer

et al. 2017

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BackgroundAt present, much attention has been focused on the beneficial effects of natural products on the human health due to their high efficacy and low adverse effects. Among them, polyphenolic compounds are known as one of the most important and common classes of natural products, which possess multiple range of health-promotion effects including anti-inflammatory and antioxidant activities. A plethora of scientific evidence has shown that polyphenolic compounds possess beneficial effects on the central nervous system.MethodsData were collected from Web of Science (ISI Web of Knowledge), Medline, Pubmed, Scopus, Embase, and BIOSIS Previews (from 1950 to 2015), through searching of these keywords: “chlorogenic acid and mental diseases” and “chlorogenic acid and neuroprotection”.ResultsChlorogenic acid is known as one of the most common polyphenolic compounds, and is found in different types of fruits and vegetables, spices, wine, olive oil, as well as coffee. The potential neuroprotective effects of chlorogenic acid have been highlighted in several in vitro and in vivo studies. This review critically analyses the available scientific evidence regarding the neuroprotective effects of chlorogenic acid, and its neuropharmacological mechanisms of action. In addition, we also discuss its biosynthesis, sources, bioavailability and metabolism, to provide a broad perspective of the therapeutic implications of this compound in brain health and disease.ConclusionThe present review showed that chlorogenic acid possesses neuroprotective effects under the both in vitro and in vivo models.

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UHPLC–MS quantification of coumarin and chlorogenic acid in extracts of the medicinal plants known as guaco (Mikania glomerata and Mikania laevigata)

Cited by 35 publications

References 18 publications

Biomimetic potentiometric sensor for chlorogenic acid based on electrosynthesized polypyrrole

Biomimetic potentiometric sensor for chlorogenic acid based on electrosynthesized polypyrrole

Capability of polygonum cuspidatum extract in inhibiting AGEs and preventing diabetes

Chlorogenic Acid and Mental Diseases: From Chemistry to Medicine

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