Development of standardized extractive solution from Lippia sidoides by factorial design and their redox active profile

Updating the status quo on the extraction of bioactive compounds in agro-products using a two-pot multivariate design. A comprehensive review

“…Microwave power (640 W) and time (30 min) were the ideal parameters for ginger oil extraction utilizing SFME. Lima et al 131 used Full-FD to extract the TFC from Lippia sidoides . The significance of the extraction method, plant quantity, and extractant in flavonoid extraction was investigated using a 2 3 -factorial design.…”

“…Numerous research with related goals, such as the screeningoptimization models, have also applied Full-FD (2 k ). 131 used Full-FD to extract the TFC from Lippia sidoides. The significance of the extraction method, plant quantity, and extractant in flavonoid extraction was investigated using a 2 3 -factorial design.…”

Application of response surface methodology as mathematical and statistical tools in natural product research

“…The optimum condition was achieved with the water temperature of 95°C and two-times brewing number. Other studies developed full two-level and three-factor factorial designs for evaluating both the preparation process and extraction condition for natural products such as Ginger rhizome (Shah and Garg, 2014), Lippia sidoides (Lima et al, 2015), and a fermented product from soybean called tempeh (Yuliani et al, 2018). As reported, the fractional and full factorial designs were widely used in optimization and design screening studies because of their economic advantages and efficiency.…”

“…Optimizing extraction process Fractional FD (Khalil et al, 2011) Ginger rhizome Determining the optimum extraction conditions Full 2 3 FD (Shah and Garg, 2014) L. sidoides Evaluating the influences of variables of preparation Full 2 3 FD (Lima et al, 2015) Tempeh (a fermented product from soybean) Evaluating factors of the extraction process Full 2 3 FD (Yuliani et al, 2018) C. sinensis L. Analysis of three methylxanthines such as caffeine, theobromine, and theophylline in the matrix of tea, coffee, and human urine was done by validated RP-HPLC/UV (de Aragão et al, 2005).…”

Otimização De Método Analítico Por Espectrofotometria Para Doseamento De Taninos Totais Nas Cascas De Hymenaea Courbarill.

“…Portanto, a identificação e quantificação dos efeitos de fatores que, possam atuar sobre a qualidade dos parâmetros de extração, permitem promover ajustes operacionais capazes de maximizar a qualidade e minimizar a variabilidade do processo. Nesse contexto, inseremse os planejamentos fatoriais que produzem dados capazes de detectar e estudar o efeito destes fatores, utilizando modelos estatísticos e assegurando a obtenção de resultados com menor quantidade de erros aleatórios (CUNHA et al, 2009;LIMA et al, 2015).…”