First phytochemical studies of japecanga (Smilax fluminensis) leaves: flavonoids analysis

Petrica, Edith E.A.; Sinhorin, Adilson P.; Sinhorin, Valéria Dornelles Gindri; Júnior, Gerado M.V.

doi:10.1016/j.bjp.2014.07.020

Cited by 8 publications

(5 citation statements)

References 13 publications

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“…For the ethanolic extract of S. fluminensis the presence of phenolic compounds and flavonoids was detected, as expected (Takahashi et al, 2011). HPLC analysis was an important tool to characterize the presence of two glycoflavonoids of the quercentin group at retention times 25.5 and 34.3 minutes at a wavelength of 254 nm, these results are consistent with those found by Petrica et al (2014) at retention times of 32.0 and 25.8 minutes at a wavelength of 254 nm.…”

Section: Discussionsupporting

confidence: 84%

Toxicity and phytochemistry of eight species used in the traditional medicine of sul-mato-grossense, Brazil

et al. 2020

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The Brazilian Cerrado has several botanical species for medicinal purposes used by traditional communities and many of these plants are not included in the list of Medicinal Plants Research Program of Central Medicines. The purpose of this study was the phytochemical screening and toxicology bioassay front of Brine shrimp L. of ethanolic extracts of eight species of plants used in folk medicine of Campo Grande, Mato Grosso do Sul, Brazil. The ethanolic extracts were submitted to phytochemical screening, determination of phenolic compounds and flavonoids. Toxicological assays were carried front of Brine shrimp according to standard methodology. The analysis TLC and HPLC-DAD confirmed the predominance of phenolic compounds and derivatives, specifically for the quercetin. The most toxic was the C. affinis DC. with death at all concentrations, the A. humile A. St. Hil. showed no mortality and the other species showed intermediate toxicity. The extracts of the investigated species are rich in phenolic compounds and derivatives, specifically quercetin, and feature toxicity between moderate to high, a fact that requires attention, since much of the traditional communities rely on herbal drugs in its raw form with preventive and curative purpose, meeting the basic health care.

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Section: Discussionsupporting

confidence: 84%

Toxicity and phytochemistry of eight species used in the traditional medicine of sul-mato-grossense, Brazil

et al. 2020

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“…Added to the antioxidant study, we decided to complement this investigation and evaluated the metabolic parameters in plasma and observed that the F1 fraction had a hypocholesterolemic effect and the F2 fraction promoted hypotriglyceridemia, which leads us to suggest that the presence of the glycosylated quercetin (Petrica et al 2014) may be inducing this hypolipidemic function. In our studies, except for the alone crude extract group, all the others groups had a hypoglycemic effect when compared to the control group (table 1).…”

Section: Resultsmentioning

confidence: 99%

Investigation of the possible protective effect of Smilax fluminensis steud. leaf in mice subjected to oxidative stress by paracetamol

et al. 2021

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Paracetamol (PCM) is a drug widely used by the population as an antipyretic and analgesic. If administered in high doses it can cause liver damage, leading to hepatoxicity. The genus Smilax, found in temperate and tropical regions, is traditionally used by the population through the extract of leaves and roots for several conditions, such as in the treatment of syphilis, diabetes, asthma and as a diuretic action. Through this, Smilax fluminensis leaf extracts were used to evaluate the protective effect against oxidative stress induced by a high dose of PCM in mice that received the drug and after receiving treatment with crude extract and fractions. Plasma analysis was performed using as partate aminotransferase (AST), alanine aminotransferase (ALT), glucose, triglycerides and cholesterol, in addition to biochemical techniques such as catalase (CAT), glutathione-S-transferase (GST), reduced glutathione (GSH), ascorbic acid (ASA), substances reactive to thiobarbituric acid (TBARS) and carbonylated proteins (CARBONYL) of liver, brain and kidneys. Fraction 1 of the extract was the most promising, decreasing the plasma levels of AST and ALT, the levels of CAT and GST of the liver, together with GSH and in the renal and brain tissue there was a decrease in carbonylated proteins (PCM + F1 versus PCM ). Besides, fraction 1 proved to be hypoglycemic and hypocholesterolemic. It is concluded that fraction 1 of Smilax fluminensis leaves has good antioxidant activity in the face of the damage caused by the high dose of paracetamol.

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“…Alves et al (2008) em levantamento etnobotânico e caracterização de plantas medicinais em fragmentos florestais no município de Dourados (MS), verificaram que a espécie Smilax fluminensis é conhecida popularmente entre os moradores como japecanga-graúda, com o chá das folhas empregado como depurativo do sangue. Petrica et al (2014) Soares (2010) em pesquisa sobre a morfoanatomia, química e propagação de Smilax fluminensis, verificou que o perfil químico dos extratos metanólicos da raiz, risóforo e da folha, apresentam picos correspondente às substâncias: ácido clorogênico, ácido caféico, rutina, ácido pcumárico, ácido ferúlico e ácido trans-cinâmico (Soares, 2010).…”

Section: Metodologiaunclassified

Morfologia de Smilax fluminensis (Smilacaceae): uma espécie medicinal no município de Alta Floresta, Mato Grosso

Fernandes

2022

Sci. Elec. Arch.

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A espécie Smilax fluminensis Steud. (Smilacaceae) é nativa no Brasil com distribuição nas regiões norte, nordeste, centro-oeste e sudeste, conhecida como cipó-quina, cipó-cruz, japecanga, japicanga, quina-cipó, raiz-de-china e salsa, com registro na medicina popular desde o século XIX. O trabalho teve como objetivo descrever a morfologia de S. fluminensis no município de Alta Floresta, Mato Grosso, além de apresentar fotografias dos órgãos vegetativos e reprodutivos, comentários taxonômicos, fitogeográficos e medicinais. O estudo foi realizado entre setembro de 2020 e outubro de 2021, com coletas de ramos férteis em fragmentos florestais na comunidade São Bento, município de Alta Floresta (MT), herborizadas e depositadas no Herbário da Amazônia Meridional (HERBAM) conforme metodologias usuais. A descrição morfológica foi realizada no Laboratório de Morfologia Vegetal nas dependências do HERBAM, da Universidade do Estado de Mato Grosso, Campus Universitário de Alta Floresta. Foi realizada fazendo uso de materiais secos e frescos com o uso de um estereomicroscópio e terminologias usuais. Smilax fluminensis é uma liana dioica e se caracteriza pelos ramos com 1-3 catáfilos, bainhas com margens expandidas, pecíolos com duas gavinhas, lâminas adultas cordadas, coriáceos, flores estaminadas com 6 tépalas, 6–7 × 1,8–2 milímetros de comprimento e frutos quando maduros alaranjados. As flores pistiladas também podem chegar até 8 tépalas, demonstrando essa pequena variação no número de tépalas. Em Alta Floresta, a planta é conhecida como japecanga, utilizada a decocção da raiz para problemas de sangue sujo, feridas persistentes, dores nos ossos, reumatismo, artrite e problemas urinários. É uma espécie com a presença de flavonoides e ácidos fenólicos, eficientes como antioxidante, anti-inflamatória e antirreumática, principalmente. O entendimento da morfologia, amparado por revisões taxonômicas, permite aprofundar os estudos das espécies com importância de uso na flora brasileira, como na medicina popular.

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First phytochemical studies of japecanga (Smilax fluminensis) leaves: flavonoids analysis

Cited by 8 publications

References 13 publications

Toxicity and phytochemistry of eight species used in the traditional medicine of sul-mato-grossense, Brazil

Toxicity and phytochemistry of eight species used in the traditional medicine of sul-mato-grossense, Brazil

Investigation of the possible protective effect of Smilax fluminensis steud. leaf in mice subjected to oxidative stress by paracetamol

Morfologia de Smilax fluminensis (Smilacaceae): uma espécie medicinal no município de Alta Floresta, Mato Grosso

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