Prevalence of respiratory epithelial adenomatoid hamartomas (REAH) associated with nasal polyposis: an epidemiological study – how to diagnose

Issa, Maria Julia Abrão; Oliveira, Vitor Ramos Ribeiro de; Nunes, Flávio Barbosa; Vasconcelos, Luís Otávio Giovanardi; Souza, Luiz Felipe Bartolomeu; Cherobin, Giancarlo Bonotto; Guimarães, Roberto Eustáquio Santos

doi:10.1016/j.bjorl.2021.09.009

Cited by 4 publications

(5 citation statements)

References 24 publications

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“…REAH can exist in isolation or association with other inflammatory processes, with nasal polyps (NP) being the most frequent 5,7 . In previous reports, REAH is found in about 30% to 55% of patients who undergo primary or revision surgery for NP 3,8–10 . In addition, REAH and CRSwNP are easily confused in terms of symptoms.…”

Section: Discussionmentioning

confidence: 99%

“…Therefore, the location measured varied from person to person. Because REAH grows diffusely in the bilateral OCs, the lesion may be present throughout the entire length of the OCs or be located anteriorly or posteriorly 3 . Therefore, to increase the universality and the comparability of measurements, we set up a relatively standardized image measurement method.…”

Section: Discussionmentioning

confidence: 99%

“…1 Emerging evidence indicates that REAH is most frequent in the bilateral olfactory clefts (OCs) and the superior and posterior end of nasal septum. 2,3 Computed tomography (CT) is of great value for diagnosing REAH. The typical manifestation of REAH on CT is the enlargement and opacification of bilateral OCs areas.…”

Section: Introductionmentioning

confidence: 99%

“…Respiratory epithelial adenomatoid hamartoma (REAH) is a benign lesion first reported in 1995 1 . Emerging evidence indicates that REAH is most frequent in the bilateral olfactory clefts (OCs) and the superior and posterior end of nasal septum 2,3 . Computed tomography (CT) is of great value for diagnosing REAH.…”

Section: Introductionmentioning

confidence: 99%

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Predictive significance of computed tomography in bilateral sinonasal respiratory epithelial adenomatoid hamartoma

Zhang

Wei

et al. 2023

Int Forum Allergy Rhinol

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Predictive significance of computed tomography in bilateral sinonasal respiratory epithelial adenomatoid hamartoma

Zhang

Wei

et al. 2023

Int Forum Allergy Rhinol

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“…Similar to other sinonasal masses, patients with REAH can present with symptoms of nasal obstruction, nasal discharge, facial pressure, or olfactory impairment 578 . REAH can present as an isolated nasal lesion or with concurrent inflammatory nasal polyposis 573,575,577–579 . In the most recent systematic review of 441 cases of REAH, 34.9% were isolated lesions and 50.1% occurred with nasal polyposis 580 .…”

Section: Benign Mass‐occupying Lesionsmentioning

confidence: 99%

International Consensus Statement on Allergy and Rhinology: Sinonasal Tumors

Kuan

Wang

Adappa

et al. 2024

Int Forum Allergy Rhinol

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BackgroundSinonasal neoplasms, whether benign and malignant, pose a significant challenge to clinicians and represents a model area for multidisciplinary collaboration in order to optimize patient care. The International Consensus Statement on Allergy and Rhinology: Sinonasal Tumors (ICSNT) aims to summarize the best available evidence and presents 48 thematic and histopathology‐based topics spanning the field.MethodsIn accordance with prior ICAR documents, ICSNT assigned each topic as an Evidence‐Based Review with Recommendations, Evidence‐Based Review, and Literature Review based on level of evidence. An international group of multidisciplinary author teams were assembled for the topic reviews using the Preferred Reporting Items for Systematic Reviews and Meta‐Analyses format, and completed sections underwent a thorough and iterative consensus‐building process. The final document underwent rigorous synthesis and review prior to publication.ResultsThe ICNST document consists of 4 major sections: general principles, benign neoplasms and lesions, malignant neoplasms, and quality of life and surveillance. It covers 48 conceptual and/or histopathology‐based topics relevant to sinonasal neoplasms and masses. Topics with a high level of evidence provided specific recommendations, while other areas summarized the current state of evidence. A final section highlights research opportunities and future directions, contributing to advancing knowledge and community intervention.ConclusionAs an embodiment of the multidisciplinary and collaborative model of care in sinonasal neoplasms and masses, ICSNT was designed as a comprehensive, international, and multidisciplinary collaborative endeavor. Its primary objective is to summarize the existing evidence in the field of sinonasal neoplasms and masses.This article is protected by copyright. All rights reserved

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