Kimura's disease with bilateral parotid involvement: a common presentation with an uncommon diagnosis

Kimura’s disease (KD) is a rare chronic inflammatory disorder of unknown etiology. The purpose of this article is to increase the awareness of clinicians regarding KD presenting with intraparotid and neck nodes which can mimic various inflammatory and neoplastic conditions. A 22-year-old man presented with a slow-growing left parotid swelling for 3 years. Ultrasound and computed tomography showed multiple enlarged intraparotid and neck nodes. Fine needle aspiration results showed lymphoid tissue hyperplasia. A diagnosis of KD was based on characteristic histopathological findings after a superficial parotidectomy in conjunction with peripheral eosinophilia. KD should be included in the differential diagnosis especially in young Asian men with slow-growing lesions and peripheral eosinophilia. Cytology by fine needle aspiration is useful to exclude malignancy but the results may be inconclusive. Surgical excision is best for definitive histopathological diagnosis, and has been the mainstay of treatment of KD.

show abstract

Kimura Disease: A Rare Case in Vietnamese Woman

Le,

Tran,

Pham

2023

Preprint

View full text Add to dashboard Cite

Background: Kimura disease (KD) is a rare benign chronic inflammatory condition that predominantly affects Asian males. It is characterized by subcutaneous tissue masses in the head and neck region, enlarged lymph nodes, increased blood eosinophilia, and elevated serum total IgE levels. In this report, we describe a rare case of KD in a young Vietnamese female. Case summary: A 31-year-old Vietnamese woman presented to the hospital with 2 masses in the bilateral cheeks and 1 mass behind the left ear that persisted for 15 years, recurrent skin itching, elevated serum total IgE levels and increased blood eosinophilia. No medical history of the individual or family was recorded. We performed an excision biopsy of the postauricular mass which revealed follicular hyperplasia with small vessel hyperplasia, diffuse infiltration of eosinophils in lymphoid follicles, and several eosinophilic microabscesses. After a comprehensive review, the final diagnosis for this patient was KD and atopic dermatitis comorbidity. Conclusion: KD is not limited to males, as this report demonstrated. The histopathological examination plays an important role in the diagnosis of KD. This case illustrated the characteristic description of KD and highlights the need for awareness of this rare disease in Asian women.

show abstract

Kimura's disease with bilateral parotid involvement: a common presentation with an uncommon diagnosis

Cited by 5 publications

References 6 publications

Speicheldrüsenschwellung und Sicca-Symptomatik bei Morbus Kimura, einer seltenen rheumatologischen Differenzialdiagnose mit wegweisend hohem IgE-Serumspiegel – eine aktuelle Übersicht nach Literatursuche

Speicheldrüsenschwellung und Sicca-Symptomatik bei Morbus Kimura, einer seltenen rheumatologischen Differenzialdiagnose mit wegweisend hohem IgE-Serumspiegel – eine aktuelle Übersicht nach Literatursuche

Kimura’s disease presenting with intraparotid and neck nodes: A case report and review of literature

Kimura Disease: A Rare Case in Vietnamese Woman

Contact Info

Product

Resources

About