Rhinophototherapy, an alternative treatment of allergic rhinitis: Systematic review and meta-analysis

Costa, Tatyana Machado Ramos; Carneiro, Fernanda Melo; Oliveira, Karen Amanda Soares de; Souza, Maria Fernanda Barbosa; Avelino, Melissa Ameloti Gomes; Wastowski, Isabela Jubé

doi:10.1016/j.bjorl.2020.12.016

Cited by 7 publications

(4 citation statements)

References 25 publications

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“…Therefore, rhinophototherapy is considered a promising non-invasive alternative treatment option for perennial or seasonal AR cases, especially low-level laser therapy (LLLT). 525 , 526 However, it has been demonstrated that photochemotherapy has certain carcinogenicity. In addition, in AD, oral psoralen plus ultraviolet A (PUVA) as a type of phototherapy also has many side effects.…”

Section: Treatmentmentioning

confidence: 99%

Pathogenesis of allergic diseases and implications for therapeutic interventions

Wang

Zhou

Zhang

et al. 2023

Sig Transduct Target Ther

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Allergic diseases such as allergic rhinitis (AR), allergic asthma (AAS), atopic dermatitis (AD), food allergy (FA), and eczema are systemic diseases caused by an impaired immune system. Accompanied by high recurrence rates, the steadily rising incidence rates of these diseases are attracting increasing attention. The pathogenesis of allergic diseases is complex and involves many factors, including maternal-fetal environment, living environment, genetics, epigenetics, and the body’s immune status. The pathogenesis of allergic diseases exhibits a marked heterogeneity, with phenotype and endotype defining visible features and associated molecular mechanisms, respectively. With the rapid development of immunology, molecular biology, and biotechnology, many new biological drugs have been designed for the treatment of allergic diseases, including anti-immunoglobulin E (IgE), anti-interleukin (IL)-5, and anti-thymic stromal lymphopoietin (TSLP)/IL-4, to control symptoms. For doctors and scientists, it is becoming more and more important to understand the influencing factors, pathogenesis, and treatment progress of allergic diseases. This review aimed to assess the epidemiology, pathogenesis, and therapeutic interventions of allergic diseases, including AR, AAS, AD, and FA. We hope to help doctors and scientists understand allergic diseases systematically.

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Section: Treatmentmentioning

confidence: 99%

Pathogenesis of allergic diseases and implications for therapeutic interventions

Wang

Zhou

Zhang

et al. 2023

Sig Transduct Target Ther

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“…However, this variation does not impact the research findings, as the wavelength range used in allergic rhinitis therapy falls within the broader range of 400 nm to 700 nm [23]. Besides, based on a journal review stated that the use of 650nm visible light can have a positive impact on allergic rhinitis patients [5]. The measurement uncertainty for the right laser diode was ±0.11, while for the left laser diode, it was ±0.05.…”

Section: Methodsmentioning

confidence: 99%

“…The study distributed 3,836 questionnaires to the participants, and the findings revealed a prevalence of allergic rhinitis at 29.3% (1,043 cases), doctor-diagnosed allergic rhinitis at 9.7% (373 cases), and cumulative allergic rhinitis at 36.2% (1,289 cases) [4]. Considering these statistics, one of the methods to cure the allergic rhinitis is phototherapy [5], [6].…”

Section: Introductionmentioning

confidence: 99%

Rhinitis phototherapy prototype with timer based on light energy

Loniza,

Junita,

Jusman

et al. 2024

IJEECS

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The set of timers in using phototherapy is major problem which has to be resolved to get a good performance of rhinitis phototherapy. This research aims to develop a prototype of phototherapy for allergic rhinitis, incorporating a timer based on light energy. The prototype utilizes a laser diode as a visible light source, specifically with a wavelength of 650 nm. The recommended safe and effective dose of light energy ranges from 1 to 10 Joules, which has been converted into minutes. Measurement tests indicate an average wavelength of 652.40 nm for the right laser, with a measurement uncertainty of ±0.11, and 653.23 nm for the left laser, with a measurement uncertainty of ±0.05. The laser diode source has an average voltage of 1.91 volts and an average current of 1.89 milliamperes, with a measurement uncertainty of ±0.00 and ±0.01, respectively. Additionally, the average discrepancy in the timer is 0.082 minutes for the 10-minute setting and 0.082 minutes for the 20-minute setting. These results confirm the effectiveness and suitability of the developed tool for practical use. The proposed method was useful for rhinitis therapy by using light energy.

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“…56 There are also clinical studies on other AR treatment methods, such as a 2021 meta-analysis that summarized 56 clinical studies on "phototherapy" for AR. 57 Although this therapy has a positive effect on AR, there are still shortcomings such as a small sample size, lack of summary on long-term side effects, and a high risk of research bias. There are also clinical studies on CR treatments such as cryotherapy, therapeutic ultrasound, and botulinum toxin.…”

Section: Hydrogen In Clinical Research On Improving Nasal Mucosal Inf...mentioning

confidence: 99%

Research Progress of Hydrogen on Chronic Nasal Inflammation

Jin¹,

Tan²,

Fan³

et al. 2023

JIR

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Chronic nasal mucosal inflammatory disease is a common nasal disease, which is involved by inflammatory cells and a variety of cytokines. Its main pathological features are inflammatory reaction, increased secretion, mucosal swelling and thickening of nasal cavity or paranasal sinuses.It mainly includes chronic rhinitis (divided into allergic rhinitis, non-allergic rhinitis), chronic sinusitis (divided into with nasal polyps, without nasal polyps type), etc.The main symptoms of chronic rhinitis are nasal itching, sneezing, runny nose, and nasal congestion. The main symptoms of chronic sinusitis are nasal congestion, purulent or sticky nasal discharge, headache, and reduced sense of smell. They are a type of disease with a high incidence rate and seriously affect the quality of human life.Although the etiology and treatment of this type of disease have been extensively studied, there are still many aspects that are unclear.Currently, oxidative stress is believed to be an important link in the pathogenesis of chronic inflammatory diseases of the nasal mucosa. Therefore, anti-oxidative stress is a direction of research for the treatment of chronic nasal mucosal inflammatory diseases.Hydrogen, as a medically therapeutic gas, has been extensively studied for its antioxidant, anti-inflammatory, and anti-damage properties, and has been used in the treatment of various diseases.Although there are relatively few studies on the use of hydrogen for nasal inflammation, its positive effects have also been found. This article systematically summarizes the relevant research on the use of hydrogen to improve chronic nasal mucosal inflammation, with the aim of clarifying the ideas and indicating the direction for further research in the future.

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Rhinophototherapy, an alternative treatment of allergic rhinitis: Systematic review and meta-analysis

Cited by 7 publications

References 25 publications

Pathogenesis of allergic diseases and implications for therapeutic interventions

Pathogenesis of allergic diseases and implications for therapeutic interventions

Rhinitis phototherapy prototype with timer based on light energy

Research Progress of Hydrogen on Chronic Nasal Inflammation

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