Total rhinectomy for nasal carcinomas

Girardi, Fábio Muradás; Hauth, Luiz Alberto; Abentroth, Aliende Lengler

doi:10.1016/j.bjorl.2019.06.002

Cited by 12 publications

(19 citation statements)

References 12 publications

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“…Basal cell and squamous cell carcinoma originating in the skin of the nose are the most common tumors that can invade the nasal cavity and be treated with surgery [4].…”

Section: Discussionmentioning

confidence: 99%

Mucosal Reconstruction with Nasal Lateral Wall Flap after Rhinectomy: Two Case Reports

Esper¹,

García²,

Laura³

et al. 2021

Int J Cancer Clin Res

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Two patients who had squamous cell carcinomas of the nasal cavity with extension to the nasal septum and previous treatments with surgery and in another with surgery and radiotherapy were treated by rhinectomy.The reconstruction of the internal mucosal lining was done with mucoperiosteal flaps from the lateral nasal wall with anterior pedicle with the assistance of endoscopes.There are few descriptions in the literature of the use of this flap to reconstruct the inner lining after rhinectomy.

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“…Basal cell and squamous cell carcinoma originating in the skin of the nose are the most common tumors that can invade the nasal cavity and be treated with surgery [4].…”

Section: Discussionmentioning

confidence: 99%

Mucosal Reconstruction with Nasal Lateral Wall Flap after Rhinectomy: Two Case Reports

Esper¹,

García²,

Laura³

et al. 2021

Int J Cancer Clin Res

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“…Standard of care includes surgery, with or without adjuvant radiotherapy in certain postoperative risk constellations or definitive radiotherapy. Although surgery can yield high control rates, organ preservation may not always be possible, even for small tumors ( 10 – 12 ). Definitive radiotherapy for malignant tumors of the nasal vestibule and the anterior nasal cavity involving the nasal vestibule may be preferable as an organ-preserving procedure ( 13 ).…”

Section: Introductionmentioning

confidence: 99%

Carbon Ion Beam Boost Irradiation in Malignant Tumors of the Nasal Vestibule and the Anterior Nasal Cavity as an Organ-Preserving Therapy

et al. 2022

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BackgroundSurgery and radiotherapy are current therapeutic options for malignant tumors involving the nasal vestibule. Depending on the location, organ-preserving resection is not always possible, even for small tumors. Definitive radiotherapy is an alternative as an organ-preserving procedure. Carbon ion beam radiotherapy offers highly conformal dose distributions and more complex biological radiation effects eventually resulting in optimized normal tissue sparing and improved outcome. The aim of the current study was to analyze toxicity, local control (LC), and organ preserving survival (OPS) after irradiation of carcinoma of the nasal vestibule with raster-scanned carbon ion radiotherapy boost (CIRT-B) combined with volumetric intensity modulated arc therapy (VMAT) with photons.MethodsBetween 12/2015 and 05/2021, 21 patients with malignant tumors involving the nasal vestibule were irradiated with CIRT-B combined with VMAT and retrospectively analyzed. Diagnosis was based on histologic findings. A total of 17 patients had squamous cell carcinoma (SCC) and 4 had other histologies. In this series, 10%, 67%, and 24% of patients had Wang stages 1, 2, and 3 tumors, respectively. Three patients had pathologic cervical nodes on MRI. The median CIRT-B dose was 24 Gy(RBE), while the median VMAT dose was 50 Gy. All patients with pathologic cervical nodes received simultaneously integrated boost with photons (SIB) up to a median dose of 62.5 Gy to the pathological lymph nodes. Eight patients received cisplatin chemotherapy. All patients received regular follow-up imaging after irradiation. Kaplan–Meier estimation was used for statistical assessment.ResultsThe median follow-up after irradiation was 18.9 months. There were no common toxicity criteria grade 5 or 4 adverse events. A total of 20 patients showed grade 3 adverse events mainly on skin and mucosa. All patients were alive at the end of follow-up. The median OPS after treatment was 56.5 months. The 6- and 24-month OPS were 100% and 83.3%, respectively. All local recurrences occurred within 12 months after radiotherapy. The median progression free survival (PFS) after treatment was 52.4 months. The 6-, 12-, and 24-month PFS rates were 95%, 83.6%, and 74.3%, respectively.ConclusionCIRT-B combined with VMAT in malignant tumors of the nasal vestibule is safe and feasible, results in high local control rates, and thus is a good option as organ-preserving therapy. No radiation-associated grade 4 or 5 acute or late AE was documented.

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“…Os cânceres de pele são as neoplasias mais comuns que afetam a cabeça e o pescoço, assim como os carcinomas oriundos das mucosas, como o carcinoma das glândulas salivares. Os locais mais propensos ao desenvolvimento do câncer de pele facial são nariz, bochechas, testa, orelhas e couro cabeludo, sendo a região nasal a mais acometida, representando cerca de 50% das neoplasias de pele da face (DROCHIOI et al, 2019;GIRARDI;HAUTH;ABENTROTH, 2019;SCHNABL et al, 2017).…”

Section: Introductionunclassified

Indicações e técnicas cirúrgicas de reconstrução da face em neoplasias malignas / Indications and surgical techniques for facial reconstruction in malignant neoplasms

Costa¹,

Silva²,

Fraga³

et al. 2021

Braz. J. Hea. Rev.

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RESUMOO presente trabalho trata-se de uma revisão narrativa de literatura com o objetivo descrever as principais indicações e técnicas utilizadas na cirurgia de reconstrução da face em tumores avançados. As neoplasias de cabeça e pescoço como, por exemplo, os variados tipos de câncer de pele, afetam uma região de grande complexidade do organismo e as cirurgias têm como principal intuito a cura da doença. No entanto, procedimentos de reconstrução facial são de suma importância pois promovem a manutenção da fisiologia e estética do indivíduo, já que a modificação facial pode causar repercussão psicológica por conta da perda de identidade do indivíduo. As técnicas de enxerto e de retalho cirúrgico se mostraram as mais eficazes para reconstrução da face em tumores avançados e suas indicações são determinadas pela necessidade tecidual e óssea, devendo, cada caso, ser avaliado individualmente. Assim, acredita-se que as cirurgias para reconstrução facial estão em constante evolução, visando resultados cada vez melhores incluindo a qualidade de vida dos pacientes.

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Total rhinectomy for nasal carcinomas

Cited by 12 publications

References 12 publications

Mucosal Reconstruction with Nasal Lateral Wall Flap after Rhinectomy: Two Case Reports

Mucosal Reconstruction with Nasal Lateral Wall Flap after Rhinectomy: Two Case Reports

Carbon Ion Beam Boost Irradiation in Malignant Tumors of the Nasal Vestibule and the Anterior Nasal Cavity as an Organ-Preserving Therapy

Indicações e técnicas cirúrgicas de reconstrução da face em neoplasias malignas / Indications and surgical techniques for facial reconstruction in malignant neoplasms

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