Side effects of intraoral devices for OSAS treatment

Teixeira, Andressa Otranto de Britto; Andrade, Ana Luiza Ladeia; Almeida, Rhita Cristina Cunha; Almeida, Marco Antônio de

doi:10.1016/j.bjorl.2017.09.003

Cited by 2 publications

(2 citation statements)

References 37 publications

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“…There is limited evidence on the long-term effects of regular MAD use on dental positioning. One study reported significant (but clinically irrelevant) changes in dentition (displacement of the incisors), in 15 patients with moderate OSA after 6 months of using a twin block MAD [ 65 ]. A recent meta-analysis found significant change in overbite and overjet with MAD use, but the authors acknowledge that the included studies had significant risk of bias [ 66 ].…”

Section: Disadvantages Of Mad Therapymentioning

confidence: 99%

Mandibular Advancement Devices for OSA: An Alternative to CPAP?

Francis

Quinnell

2020

Pulm Ther

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Obstructive sleep apnea (OSA) is a prevalent condition causing unrefreshing sleep and excessive daytime sleepiness. It has individual socioeconomic impacts and, through association with increased risk of road traffic accidents, diabetes, and cardiovascular disease, OSA is a public health issue. Continuous positive airway pressure (CPAP) is the first-line treatment for moderate-to-severe OSA. It is effective in improving excessive daytime sleepiness and quality of life. There is also evidence that CPAP therapy has cardiovascular benefits although nature and extent remain uncertain. Despite its benefits, a significant proportion of patients are unable to tolerate CPAP. There are also patients with mild but symptomatic disease, for whom CPAP is usually not available or appropriate, so there is a need for other treatment options. Mandibular advancement devices (MADs) offer an effective alternative to CPAP and can improve daytime symptoms and quality of life. There are many devices available, representing a range of complexity and cost. It is challenging to properly evaluate the effectiveness of this ever-evolving range. The more basic MADs are cheaper and more accessible but are less well tolerated. More complex devices are better tolerated and may be more effective. However, they are more expensive and often require dental expertise, so access is more limited. Efforts continue to try to improve accessibility to effective MAD therapy. Alongside increasing awareness, this may be facilitated by developing and refining devices that could be fitted by non-dental clinicians, and potentially by patients themselves. Research efforts need to focus on determining how to efficiently identify patients who are likely to respond to MAD therapy, so as to improve clinical and cost-effectiveness of OSA therapy overall.

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Section: Disadvantages Of Mad Therapymentioning

confidence: 99%

Mandibular Advancement Devices for OSA: An Alternative to CPAP?

Francis

Quinnell

2020

Pulm Ther

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“…33 Although the occurrence ranges anywhere from 0% (6 months treatment) to 51% (11 years treatment), it appears that the longer the treatment, the higher the POB incidence among these patients. [34][35][36][37][38][39] As these appliances hold the mandible in a forward and vertically opened position to prevent the pharyngeal airway from collapsing, 34 transient contracture of the inferior lateral pterygoid muscle, forward and downward positioning of lower arch and protrusion of mandibular incisors have been suggested to contribute to the occurrence of POB. [34][35][36]40 Syndromes and Class III Patients with amelogenesis imperfecta (AI), 41,42 achondroplasia, 14 Apert Syndrome, 13 and DMD 22,23 have all been reported to have POB as part of their craniofacial manifestations.…”

Section: Mandibular Advancement Therapymentioning

confidence: 99%

<p>Review of Etiology of Posterior Open Bite: Is There a Possible Genetic Cause?</p>

Huang¹,

Shan²,

Ang³

et al. 2020

CCIDE

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Posterior open bite (POB) is one of the most severe malocclusions that can impair patients' masticatory functions, yet it is also a condition that is poorly understood and not well studied. Most reported cases are either sporadic or idiosyncratic with a diverse yet poorly understood etiology. Although primary failure of eruption (PFE), lateral tongue thrust, and certain medical syndromes or pathology of the temporomandibular joints have all been shown to cause POB, the complex interplay of environmental and genetic factors makes its etiopathogenesis a difficult subject to understand and investigate. Here, we provide a comprehensive review of the etiology of posterior open bite. Additionally, a genetic cause for POB is proposed through a report of an apparently non-syndromic familial case series with high POB penetrance across two generations. Further investigations of the gene(s) and mechanism(s) involved can not only provide a unique opportunity to better understand POB and the intricate muscular-occlusal relationship, but also offer powerful insight into the most effective approaches to clinical management of these (and potentially other) malocclusions.

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Side effects of intraoral devices for OSAS treatment

Cited by 2 publications

References 37 publications

Mandibular Advancement Devices for OSA: An Alternative to CPAP?

Mandibular Advancement Devices for OSA: An Alternative to CPAP?

<p>Review of Etiology of Posterior Open Bite: Is There a Possible Genetic Cause?</p>

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