Aggressive osteoblastoma of the temporal bone: an unusual cause of facial palsy

Dixit, Rashmi; Gupta, Swati; Chowdhury, Veena; Khurana, Nita

doi:10.1016/j.bjorl.2015.10.014

Cited by 6 publications

(8 citation statements)

References 9 publications

(11 reference statements)

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“…2,4,10,[13][14][15] The bone contour may be markedly expanded and exhibit a thinned, disrupted cortex. 2,4,10,[13][14][15][16] The tumor stroma is characteristically rich in blood vessels. On microscopy, AO shows many similarities to conventional osteoblastoma.…”

Section: Discussionmentioning

confidence: 99%

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Aggressive Osteoblastoma of Temporal Bone Causing Facial Palsy in a 9-year-old Child: A Case Report Based on 2020 WHO Classification of Bone Tumors

Cambruzzi,

Furian,

Botega

et al. 2023

Arquivos Brasileiros de Neurocirurgia: Brazilian Neurosurgery

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Aggressive osteoblastoma (AO) is an uncommon bone tumor that represents a borderline lesion between osteoblastoma and osteosarcoma. The vertebral column, the sacrum, the pelvis, and jaw/craniofacial bones are primarily affected. Aggressive osteoblastoma does not metastasize and is treated by surgical resection. The authors report a case of AO in a 9-year-old female patient presenting with 5th and 7th cranial nerve palsy. Prior pathological history included resection of an expansile nodule in the left temporal bone. Conventional radiological examination and computed tomography (CT) of the skull revealed an osteoblastic lesion arising in the petrous portion of the left temporal bone, measuring 5.2 cm in the largest dimension. The patient was subjected to partial surgical resection of the process. Microscopy revealed a primary neoplastic bone composed of numerous epithelioid round osteoblasts disposed in solid sheets and with mild atypia, large eosinophilic cytoplasm, and an eccentric, ovoid nucleus. The process exhibited loose stroma, low mitotic index, osteoid formation, and a few osteoclast-like multinucleated giant cells. The diagnosis of AO was thus established. After 5 months of clinical follow-up, the patient is asymptomatic, without evidence of tumoral growth on CT scans.

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Section: Discussionmentioning

confidence: 99%

“…The presence of benign osteoclast-like multinucleated giant cells and secondary aneurysmal bone cysts are common features. 2,4,7,10,13,15,17,18 Aggressive osteoblastomas show 1 to 4 typical mitotic figures per 20 high-power fields. Necrosis is uncommon, and chondroid/cartilaginous differentiation has not been described.…”

Section: Discussionmentioning

confidence: 99%

Aggressive Osteoblastoma of Temporal Bone Causing Facial Palsy in a 9-year-old Child: A Case Report Based on 2020 WHO Classification of Bone Tumors

Cambruzzi,

Furian,

Botega

et al. 2023

Arquivos Brasileiros de Neurocirurgia: Brazilian Neurosurgery

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“…The rising from the temporal bone is extremely unusual, with only 26 cases described in the literature. [ 2 3 4 5 6 ]…”

Section: Discussionmentioning

confidence: 99%

“…[ 1 ] Twenty-six cases of osteoblastoma involving the temporal bone have been reported so far. [ 2 3 4 5 6 ] Localized pain and swelling with occasional 7 th and 8 th cranial nerve compression are the main presenting clinical features. Raised intracranial pressure (ICP) caused by mass effect has been reported in one case, and in another case, 6 th nerve palsy caused by compression of the cavernous sinus has been described.…”

Section: Introductionmentioning

confidence: 99%

Osteoblastoma mimicking an idiopathic intracranial hypertension syndrome

et al. 2017

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Osteoblastomas are rare, benign bone tumors mainly arising from the long bones and the posterior vertebral arches. Skull localizations account for approximately 15% of cases. A total amount of thirty cases involving the temporal bone are reported in the literature. Clinical presentation of temporal osteoblastomas often includes local pain and swelling, while 7th and 8th cranial nerve impairment is rare. We report the novel finding of increase intracranial pressure syndrome secondary to dominant transverse-sigmoid sinus junction compression caused by a small temporal bone osteoblastoma. Excision of the tumor with the restoration of venous flow in the sigmoid sinus was followed by a prompt clinical improvement. In the management of patients with a venous sinus compression, restoration of venous drainage should be a priority.

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“…This rare tumor is histologically benign, osteoid-forming vascular neoplasm [8] and accounts for less than 1% of all bone lesions, and 15% of these tumors affect the head region [9] . It occurs twice as often in men, and usually in their mid-thirties.…”

Section: Discussionmentioning

confidence: 99%