Derivation of a clinical decision rule for predictive factors for the development of pharyngocutaneous fistula postlaryngectomy

Cecatto, Suzana B.; Monteiro‐Soares, Matilde; Henriques, Teresa; Monteiro, Eurico; Moura, Carla Isabel Ferreira Pinto

doi:10.1016/j.bjorl.2014.09.009

Cited by 28 publications

(15 citation statements)

References 33 publications

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“…A multivariate logistic regression (high academic achievement = 1/low academic achievement = 0) was carried out to identify which factors were independently associated with academic achievement using the Enter method. Variables which obtained p < 0.2 in the bivariate analysis were entered in the model [74,75]. Independent variables were introduced by blocks: Model 1 included socio-demographic and school variables.…”

Section: Discussionmentioning

confidence: 99%

Is Academic Achievement Related to Mediterranean Diet, Substance Use and Social-Cognitive Factors: Findings from Lebanese Adolescents

et al. 2020

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There is substantial evidence that good academic performance significantly enhances the prospects of success for adolescents in terms of employment, social status, quality of life and health. Identifying which factors are correlated to good academic achievement and which factors may need to be addressed by policies is crucial. Despite its importance, there is insufficient data concerning factors associated with academic achievement in the Middle East, particularly Lebanon. This study assessed the association of lifestyle, socio-demographics and motivational factors with academic achievement of Lebanese adolescents. Grade 10 and 11 Lebanese adolescents aged 15 to 18 years (n = 600), from private and public schools in Beirut and the Mount Lebanon area, completed a multi-component questionnaire assessing health behaviors, socio-demographic characteristics and motivational factors. Height and weight were physically measured and, subsequently, Body Mass Index was calculated. Academic achievement was assessed using self-reported grades and was categorized into high and low. Associations between all factors and academic achievement were tested using logistic regression models. Adherence to the Mediterranean diet, high self-efficacy and intention were positively associated with academic achievement, whereas smoking was associated with poor achievement. Our findings support the need for targeting adolescents with an unhealthier lifestyle and focusing on socio-cognitive determinants interventions aimed at enhancing academic achievement.

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Section: Discussionmentioning

confidence: 99%

Is Academic Achievement Related to Mediterranean Diet, Substance Use and Social-Cognitive Factors: Findings from Lebanese Adolescents

et al. 2020

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“…11 Some studies reported the lower rate of 5-year survival for patients with persistent PCF. 12 Several studies showed many potential risk factors for PCF formation; some studies indicated the role of the previous radiotherapy in the fistula formation, 9,13 but some others showed no relationship between the history of radiotherapy and fistula formation. 14,15 A multi-variant analysis by Maria Casasayas et al, 16 indicated that prolonged surgery and lower hemoglobin level after surgery were the most predictive risk factors for fistula formation alongside neck dissection, malnutrition, lower serum albumin level, preoperative tracheostomy, marginal involvement, high-grade tumor, and systemic comorbidities such as hypertension and hypothyroidism.…”

Section: Discussionmentioning

confidence: 99%

Effect of Low-Pressure Drainage Suction on Pharyngocutaneous Fistula After Total Laryngectomy

Delarestaghi

Ahmadi

Firouzabadi

et al. 2020

Ann Otol Rhinol Laryngol

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Objective: Pharyngocutaneous fistula (PCF) is one of the most severe multifactorial complications following laryngectomy. The current study aimed at determining the effect of a low-pressure vacuum drain on the incidence of PCF after total laryngectomy. Methods: The current randomized clinical trial was conducted on 35 patients undergoing total laryngectomy in Hazrat Rasoul Akram and Firoozgar hospitals in Tehran, Iran. The subjects were divided into the vacuum drain (n = 15) and control (without vacuum drain) (n = 20) groups. The incidence of PCF and the recovery time were recorded. Results: The rate of PCF formation from the stoma and wound edges was significantly lower in the low-pressure vacuum drain group than in the control group (6.7% vs 40%) ( P < .05). There was no significant difference between the groups in time to recovery from PCF. Conclusion: The low-pressure vacuum drain method is effective in reducing the incidence of PCF after total laryngectomy.

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“…Erdağ et al (14) reported that control of concurrent systemic disease, preservation of hematological values in the pre-and post-operative period, ensuring adequate nutrition, and preference of erythrocyte suspensions for transfusion are key points in the prevention of PCF development. In addition to these traditionally specified risk factors, it is stated that wound classification, reconstruction with free flap compared to primary closure and ASA classification are among the important risk factors (15,16). Dedivitis et al (17) reported that, except for the mentioned risks, advanced primary tumor, performance status of patient are the important risk factors.…”

Section: Discussionmentioning

confidence: 99%

Development of Pharyngocutaneous Fistula after Total Laryngectomy: The Predictive Value of C-reactive Protein/Albumin Ratio

Yücel

Aydemir³

et al. 2020

Acta Med. (Hradec Kralove, Czech Repub.)

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Background: We aimed to evaluate whether C-reactive protein(CRP)/ Albumin ratio (CAR) performed in the early postoperative period after total laryngectomy could be a predictive factor for the development of pharyngocutaneous fistula (PCF). Methods: The files of patients with laryngeal squamous cell carcinoma who underwent total laryngectomy between January 2005 and January 2019 were retrospectively reviewed. Patients were divided into two groups: patients with PCF (PCF group) and without (Non-PCF group). CAR values and risk factors were compared between groups. Results: The overall incidence of PCF was 23.2%. There was a statistically significant difference between the two groups in terms of CRP and CAR levels (p = 0.001). The CAR value of 27.05 (sensitivity = 75.0% , specificity 68.2%, area under curve (AUC) = 0.742, 95% confidence interval 0.616–0.868) was determined as a cutoff value to describe the development of fistula in the early postoperative period. In multiple linear regression analysis, there was an independent relationship between presence of PCF and previous RT and CAR value. Conclusions: CAR, performed in the early postoperative period, may be a new and useful marker for predicting PCF after total laryngectomy.

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Derivation of a clinical decision rule for predictive factors for the development of pharyngocutaneous fistula postlaryngectomy

Abstract: A clinical decision rule was created to identify patients with high risk of pharyngocutaneous fistula development. Prognostic accuracy measures were substantial. Nevertheless, it is essential to conduct larger prospective studies for validation and refinement.

Cited by 28 publications

References 33 publications

Is Academic Achievement Related to Mediterranean Diet, Substance Use and Social-Cognitive Factors: Findings from Lebanese Adolescents

Is Academic Achievement Related to Mediterranean Diet, Substance Use and Social-Cognitive Factors: Findings from Lebanese Adolescents

Effect of Low-Pressure Drainage Suction on Pharyngocutaneous Fistula After Total Laryngectomy

Development of Pharyngocutaneous Fistula after Total Laryngectomy: The Predictive Value of C-reactive Protein/Albumin Ratio

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