Prevalence of the Helicobacter pylori in the tonsils and adenoids

Bayındır, Tuba; Toplu, Yüksel; Otlu, Barış; Yakupoğulları, Yusuf; Yıldırım, Oğuzhan; Kalcıoğlu, M. Tayyar

doi:10.1016/j.bjorl.2014.08.018

Cited by 13 publications

(7 citation statements)

References 27 publications

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“…The stomach is accepted as a natural reservoir for H. pylori, while tissues such as the gallbladder, gingiva, oral lesions, and dental plaques are shown to be potential extra-gastric reservoirs [8] . Furthermore, recent studies suggest that H. pylori can also be located in nasal polyps, the nasal and/or sinus mucosa, saliva, oropharyngeal aphthous lesions, adenotonsillar tissue, pharyngeal lymphoid tissue, and larynx [9][10][11][12] .…”

Section: Epidemiology and Pathogenesismentioning

confidence: 99%

“…In the literature, numerous articles have reported different results regarding the correlation between H. pylori infection and rhinitis, sinusitis, adenoiditis or adenoid hyperplasia, otitis media, tonsillitis or tonsil hypertrophy. As a result of these studies, the pathogenicity and/or possible role of H. pylori remains controversial in this diseases [10,17,25] . The discordance in these studies may be related to difference in sample quantity, study design, or methodology.…”

Section: Reservoirs Of Helicobacter Pylori In the Upper Respiratory Tmentioning

confidence: 99%

“…In the light of this knowledge, the association between H. pylori infection and some gastrointestinal malignancies has been demonstrated in different studies [1,6,7] . However, the potential relationship between H. pylori and malignancies of extra-gastric sites still remains controversal [2,[8][9][10][11][12] .…”

Section: Introductionmentioning

confidence: 99%

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Association between Helicobacter pylori and Pharyngolaryngeal Carcinomas: The Role in the Development and Prognostic Significance

Bayındır¹,

Bayındır²,

Koca³

et al. 2019

mjima

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Helicobacter pylori dünyada yaygın olarak bulunan ve insanları enfekte eden bir bakteridir. Bu Gram-olumsuz mikroorganizma, mikroaerofilik, spiral ya da eğimli şekildedir ve ayrıca üreaz, katalaz ve oksidaz olumludur. Midedeki asidik ortamda yaşamını sürdürme özelliğine sahiptir. Günümüzde H. pylori'nin gastrik ülser ve malign lezyonlarda rolü olduğu ispatlanmıştır. Dahası, H. pylori'nin kardiyovasküler, dermatolojik, immünolojik, nörolojik, hematolojik, oftalmolojik, jinekolojik, endokrinolojik ve hepatobiliyer hastalıklar gibi çeşitli sistemik hastalıkların nedeni olabileceği bildirilmiştir. Ayrıca literatürde H. pylori enfeksiyonu ile rinit, sinüzit, adenoidit/adenoid hipertrofi, otitis media, tonsillit/tonsil hipertrofisi gibi benign üst solunum yolu hastalıkları arasında olumlu ya da olumsuz ilişki gösteren çok sayıda çalışma bulunmaktadır. Ancak H. pylori'nin patogenezdeki rolü veya bu hastalıklarla olan ilişkisi ile ilgili tartışmalar devam etmektedir. Bununla birlikte bazı çalışmalarda H. pylori'ye karşı oluşan sistemik immün ya da enflamatuvar yanıtın bazı sistemik hastalıkların veya malignitelerin nedeni olabileceği bildirilmiştir. Her ne kadar H. pylori'nin üst ve alt solunum yolu benign ve malign hastalıklarındaki rolü hakkında çalışmalar bulunsa da, H. pylori enfeksiyonu ve solunum yolu hastalıkları arasındaki patofizyolojik ilişkiyi ortaya koymak için daha ileri çalışmalara gereksinim bulunmaktadır. Bu derleme ile literatürde H. pylori ve solunum yollarının hem benign hem de malign hastalıkları arasındaki hem olumlu hem de olumsuz ilişkiyi gösteren çalışmaların özetlenmesi hedeflendi.

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Section: Epidemiology and Pathogenesismentioning

confidence: 99%

Section: Reservoirs Of Helicobacter Pylori In the Upper Respiratory Tmentioning

confidence: 99%

See 1 more Smart Citation

Association between Helicobacter pylori and Pharyngolaryngeal Carcinomas: The Role in the Development and Prognostic Significance

Bayındır¹,

Bayındır²,

Koca³

et al. 2019

mjima

Self Cite

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“…Many studies have demonstrated the presence of H. pylori in upper respiratory system mucosa and the bacterium’s potential role in causing diseases, such as sinusitis, adenotonsillar hypertrophy, pharyngitis, and laryngitis (11-13). …”

Section: Introductionmentioning

confidence: 99%

Detection of Helicobacter pylori in the Bronchoalveolar Lavage of Patients with Lung Cancer Using Real-Time PCR

Fekri

Bajgani

Shafahi

et al. 2016

Jundishapur J Microbiol

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BackgroundLung cancer is one of the most common causes of death worldwide. Although smoking and environmental pollutants are the most important risk factors of lung cancer, the role of infectious causes should also be considered in the pathogenesis and progress of lung cancer.ObjectivesThis study examined the relationship between Helicobacter pylori and lung cancer through serology, real-time PCR, and urease tests.MethodsThis descriptive cross-sectional study was conducted on 52 adult patients with lung cancer who were selected after having their history taken and being physically examined by a pulmonologist. Then, the patients underwent a bronchoscopy, a BAL, and biopsy sampling. A urease test was run for each biopsy sample, real-time PCR was used for each BAL sample, and H. pylori serology was used for each patient’s serum.ResultsThe patients’ average age was 60.65 ± 9.15 years; 11.5% were female and 88.5% were male. The prevalence of H. pylori in lung cancer patients was 11.5% according to the BAL PCR test, 92.3% according to the serology test, and 3.8% according to the urease test.ConclusionsThe results demonstrated an association between of lung cancer and H. Pylori infection via the hypothesis of direct damage and chronic inflammation through inhalation and aspiration and the systematic immune response induced by H. pylori colonization. Helicobacter pylori, together with a host’s genetic predisposition and other environmental risk factors, could be attributed to the induction of lung cancer.

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“…This gram-negative and microaerophilic bacterium colonizes the gastric mucosa and duodenum and causes chronic gastritis as well as diseases such as gastric adenocarcinoma, MALT lymphoma, gastric & duodenal ulcers [2][3][4]. While the stomach is considered the main reservoir of Helicobacter pylori, new studies suggest that adenotonsillar tissue is prone to Helicobacter pylori colonization, but the results are highly contradictory [5][6][7][8][9]. Due to the fact that the tonsils and adenoids are located at the entrance of the gastrointestinal tract and respiratory tract, so in this study we examine the tonsils and adenoids as one of the possible reservoirs for Helicobacter pylori.…”

mentioning

confidence: 99%

Prevalence of Helicobacter Pylori in the Tonsil and Adenoid Tissue of Adenotonsillectomy Patients with Rapid Urease Test

Yousefi

Shoghi

Taheri

et al. 2020

hrjbaq

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Introduction: Helicobacter pylori is a micro-aerophilic gram-negative bacteria that is colonized in the gastric mucosa and duodenum using its own factors such as urease, catalase and lipase. While the stomach is considered the main source of it, other tissues such as the Walder ring, gallbladder, gums, oral lesions and dental plaque have also been suggested as potential sources. Recent studies suggest that adenotonsillar tissue is susceptible to Helicobacter pylori colonization, but the results are very contradictory. Therefore, in the present study, we tried to evaluate the presence of this bacterium in this tissue. Materials and Methods: In this cross-sectional study, which was conducted from October 2017 to October 2016, cases of adenotonsillectomy surgery without a history of antibiotics and bismuth in the last two weeks were included in the study. 2 to 5 mm of samples were removed and placed in a filled vial up to half of the urease test kit solution. Change of color of the solution from yellow to purple was a positive result and no color change after a maximum of one hour, a negative result was recorded. Results: A total of 114 samples were obtained from 64 patients, of which 63 were tonsil samples and 51 were adenoids. In 5 samples (all tissues removed from the tonsil), the urease test was positive (4.4%) and the other 109 samples (95.6%) were negative. There was no significant relationship between urease test result with tissue type (P = 0.063), reason for surgery (P = 0.65) and age (P = 0.07). Conclusion: Our results showed that Helicobacter pylori colonization in adenotonsillar tissue had a frequency of 4.4%, in other words, 5 out of 64 patients (7.8%) had tonsil colonization with Helicobacter pylori, which showed a small amount.

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Prevalence of the Helicobacter pylori in the tonsils and adenoids

Abstract: This study suggests that children are exposed to Hp at an early age of their life in this province. Hp may have a role in the pathogenesis of chronic adenotonsillitis, especially in endemic areas.

Cited by 13 publications

References 27 publications

Association between Helicobacter pylori and Pharyngolaryngeal Carcinomas: The Role in the Development and Prognostic Significance

Association between Helicobacter pylori and Pharyngolaryngeal Carcinomas: The Role in the Development and Prognostic Significance

Detection of Helicobacter pylori in the Bronchoalveolar Lavage of Patients with Lung Cancer Using Real-Time PCR

Prevalence of Helicobacter Pylori in the Tonsil and Adenoid Tissue of Adenotonsillectomy Patients with Rapid Urease Test

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