Perioperative parathyroid hormone measurements in thyroid surgery: one stone to hit three birds

Terkawi, Abdullah Sulieman; Aldhahri, Saleh

doi:10.1016/j.bjorl.2014.08.015

Cited by 1 publication

(1 citation statement)

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“…The variation in baseline PTH might be secondary to population norms, or more likely to the differences in vitamin D level and incidence of deficiency. 17 Therefore, the use of percent of change, rather than absolute PTH values, would probably account for this variable. Al-Dhahri et al 10 tested the accuracy of post thyroidectomy calcium level and PTH level at different times post-operatively, they found that PTH measurements at 6, 12, 20, 32, and 44 hr had high predictive probability to detect clinical hypocalcemia; Despite the fact that Ca accuracy markedly improved in the second day, it never reached accuracy of PTH measurement.…”

Section: Resultsmentioning

confidence: 99%

Role of Intact Parathyroid Hormone (iPTH) Level as an Early Predictor of Postoperative Hypocalcemia after Total Thyroidectomy for Simple Multi-Nodular Goiter

Hamed

Afifi

2019

Ain Shams Journal of Surgery

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Background: Postoperative hypocalcaemia, secondary to hypoparathyroidism, is the most common complication observed in patients who undergo bilateral thyroid resection. Although hypocalcaemia is self-limiting in most patients and does not require treatment, symptomatic hypocalcemia is of concern. The aim of this research was to identify PTH-24h post-operatively as a simple predictor of early postoperative hypocalcemia following total thyroidectomy for simple multi-nodular goiter.Methods: Fifty patients undergoing total thyroidectomy for simple multi-nodular goiter were included in a prospective controlled study with follow up of 48 hours postoperatively for the development of hypocalcemia both clinically and biochemically correlating it to the level of serum iPTH thus allocating patients in two groups; those who developed hypocalcemia (whether clinically or biochemically) and those who didn`t.Results: A highly significant difference between PTH percent of decline was noted for the patients who developed biochemical hypocalcaemia and those who did not. Conclusion:Serum PTH 24-h after total thyroidectomy is a reliable early predictor of hypocalcemia.

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Section: Resultsmentioning

confidence: 99%