2018
DOI: 10.1016/j.bjm.2018.05.002
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Abstract: This study compares patients with and without non-viral microbial keratitis in relation to sociodemographic variables, clinical aspects, and involved causative agent. Clinical aspects, etiology and therapeutic procedures were assessed in patients with and without keratitis that were diagnosed in an Eye Care Center in Campo Grande, MS, Brazil. Patients were divided into two groups: (a) cases: 64 patients with non-viral microbial keratitis diagnosed at biomicroscopy; and (b) controls: 47 patients with other eye … Show more

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Cited by 5 publications
(4 citation statements)
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“…A corneal ulcer is a significant cause of corneal blindness worldwide. e clinical profile and spectrum of microorganisms responsible for corneal ulceration are variables depending on the patient population, geographic location, and climatic conditions [8][9][10]. However, to the best of our knowledge, there are limited study reports on bacterial and fungal pathogen burden among patients suffering from corneal ulcers in Gondar and the country of Ethiopia in general.…”
Section: Discussionmentioning
confidence: 99%
See 1 more Smart Citation
“…A corneal ulcer is a significant cause of corneal blindness worldwide. e clinical profile and spectrum of microorganisms responsible for corneal ulceration are variables depending on the patient population, geographic location, and climatic conditions [8][9][10]. However, to the best of our knowledge, there are limited study reports on bacterial and fungal pathogen burden among patients suffering from corneal ulcers in Gondar and the country of Ethiopia in general.…”
Section: Discussionmentioning
confidence: 99%
“…Several studies have evaluated the etiology, management, and outcome of microbial keratitis [5][6][7]. Demographic and geographic factors affect the distribution of the causative organisms of infectious corneal ulceration [8][9][10]. ey include pre-existing corneal disease as well as other risk factors such as contactlens wear, surgical or non-surgical trauma, and ocular surface disease, contaminated ocular medications, impaired defense mechanisms, and altered structure of the corneal surface [1,8].…”
Section: Introductionmentioning
confidence: 99%
“…Based on the advice from the Royal College of Ophthalmologists, MK should initially be treated with a broad-spectrum antibiotic able to fight both Gram-negative and Gram-positive bacteria [37]. Dual therapy targeting both Gram-negative and Gram-positive germs is usually based on topical aminoglycosides and fourth generation fluoroquinolones [38]. However, it is becoming clear that a more targeted treatment to improve the clinical outcome is going to be needed [10].…”
Section: Discussion/conclusionmentioning
confidence: 99%
“…Worldwide, bacteria are the most common cause of microbial keratitis, but a significant minority are a result of fungal infections. [3][4][5] There are important socioeconomic and geographic variations in the incidence and etiology of microbial keratitis, with fungal pathogens being more common in tropical regions and the developing world. [6][7][8] The spectrum of activity for commonly used antimicrobials is narrow when compared with the number of possible infectious agents, and as a result, distinguishing between these organisms is a first step essential in the treatment of patients with microbial keratitis.…”
mentioning
confidence: 99%