2017
DOI: 10.1016/j.bjid.2017.06.005
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A cross-sectional study assessing the pharyngeal carriage of Neisseria meningitidis in subjects aged 1–24 years in the city of Embu das Artes, São Paulo, Brazil

Abstract: Meningococcal carriage is a prerequisite for invasive infection. This cross-sectional study assessed the pharyngeal carriage prevalence in healthy subjects aged 1-24 years in Embu das Artes city, São Paulo, Brazil. Pharyngeal swabs were examined for the presence of Neisseria meningitidis. The isolates were tested for different serogroups using agglutination and polymerase chain reaction. A logistic regression model assessed any independent association between Neisseria meningitidis carriage and various risk fa… Show more

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Cited by 13 publications
(19 citation statements)
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“…1). Of these, 14 met the inclusion criteria and were included in the review, including seven studies from Brazil [33][34][35][36][37][38][39], three from Chile [40][41][42], and one each from Colombia [43], Cuba [32], Mexico [44], and Paraguay [45] (Fig. 2; Table 2).…”
Section: Literature Search Findings On Carriage In the Americasmentioning
confidence: 99%
See 1 more Smart Citation
“…1). Of these, 14 met the inclusion criteria and were included in the review, including seven studies from Brazil [33][34][35][36][37][38][39], three from Chile [40][41][42], and one each from Colombia [43], Cuba [32], Mexico [44], and Paraguay [45] (Fig. 2; Table 2).…”
Section: Literature Search Findings On Carriage In the Americasmentioning
confidence: 99%
“…From October 2011 to May 2012, Weckx and colleagues assessed carriage from a sample of 87 individuals aged 1-24 years recruited from six basic healthcare units and three schools in the Embu das Artes region of São Paulo; additional details regarding participant recruitment were not provided [36]. The study covered the period 10 months after introduction of the MenC vaccine in the national immunization program, as described above.…”
Section: Brazilmentioning
confidence: 99%
“…A partir de 2010, a maioria dos estudos passa a utilizar métodos fenotípicos e/ou genotípicos através da PCR utilizando primers diversos (ctrA, crgA, sodC, ctrB). (Gasparini et al, 2014;Sáfadi et al, 2014;Coch Gioia et al, 2015;Moraes et al, 2015;Moreno et al, 2015;Ataee et al, 2016;Weckx et al, 2017;Kim et al, 2017;Gonzales et al, 2017;van Ravenhorst et al, 2017).…”
Section: Discussionunclassified
“…A prevalência de portadores de Nm encontrada nesse estudo (2,4%) foi inferior a de outros estudos realizados no Brasil com população alvo variando de 1 a 24 anos de idade, os quais estimaram uma prevalência média de em torno de 7,9% (DE MORAES et al, 2015;NUNES et al, 2016;WECKX et al, 2017) e semelhante a estudos realizados no exterior em contextos de estratégias de vacinação e público alvo diferentes (adolescentes).…”
Section: Portadores De Neisseria Meningitidisunclassified
“…Os genótipos 10 CC e 11 ST apareceram neste estudo, sendo dois novos ST identificados pela primeira vez. Encontramos alta proporção das cepas de Nm não grupáveis, assim como em outros estudos de portadores (DIALLO et al, 2016;NUNES et al, 2016;WECKX et al, 2017;BASTA et al, 2018).…”
Section: Portadores De Neisseria Meningitidisunclassified