Human parechovirus: sepsis-like illness with pulmonary infection

Vidal, Luíne Rosele Renaud; Cavalli, Bárbara Maria; Almeida, Sérgio Monteiro de; Raboni, Sônia Mara; Nogueira, Meri Bordignon

doi:10.1016/j.bjid.2017.06.004

Cited by 1 publication

(1 citation statement)

References 5 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Clinical presentation of HPeV, similar to other echoviruses, has a broad range including asymptomatic shedding [3], severe pulmonary [4] and neurologic disease [5], and disseminated intravascular coagulation [6]. Neonates and young infants appear particularly susceptible.…”

Section: Introductionmentioning

confidence: 99%

Infant identical triplets’ presentation of human parechovirus Type 3

Weichelt

Hooper

Chow

2019

IDCases

View full text Add to dashboard Cite

IntroductionHuman parechovirus (HPeV) infections appear common across age groups, and transmission is likely fecal-oral and through respiratory secretions. Cyclical and seasonal patterns have been described; however, HPeV has likely been previously underdiagnosed due to lack of commercially available diagnostic testing.Presentation of CaseWe present identical triplets contracting HPeV Type 3.DiscussionThe clinical presentation, similar to echoviruses, is broad and includes asymptomatic shedding, severe pulmonary and neurologic disease, and disseminated intravascular coagulation. Neonates and young infants are particularly susceptible. In neonates, distinctive MRI brain findings have been described that, when combined with clinical presentation, suggest HPeV. Infection clusters have been described, and neonates with older siblings may be a risk factor.ConclusionThis case suggests that HPeV has been under-recognized in the United States, and HPeV Type 3 prevalence is likely underestimated. The case highlights variation in presentation, including lack of fever and rash, which were previously documented as common HPeV symptoms.

show abstract