2017
DOI: 10.1016/j.bjid.2017.05.005
|View full text |Cite
|
Sign up to set email alerts
|

Tuberculosis incidence among people living with HIV/AIDS with virological failure of antiretroviral therapy in Salvador, Bahia, Brazil

Abstract: Antiretroviral therapy for HIV has led to increased survival of HIV-infected patients. However, tuberculosis remains the leading opportunistic infection and cause of death among people living with HIV/AIDS. Tuberculosis has been shown to be a good predictor of virological failure in this group. This study aimed to evaluate the incidence of tuberculosis and its consequences among individuals diagnosed with virological failure of HIV. This was a retrospective cohort study involving people living with HIV/AIDS be… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
3
2

Citation Types

1
5
0
5

Year Published

2018
2018
2023
2023

Publication Types

Select...
7

Relationship

0
7

Authors

Journals

citations
Cited by 8 publications
(11 citation statements)
references
References 12 publications
1
5
0
5
Order By: Relevance
“… 19 The possible explanation could be that people living with HIV and with TB have confounding factors such as; overlapping drug toxicities, exacerbation of side effects, reduce adherence to prescribed medication, and immune reconstitution inflammatory syndrome. 32 TB weakens the immune system, which in turn facilitates viral replication. 33 HIV-infected patients with opportunistic infection may interrupt the time of taking a drug, lost follow-up, and other triple problems that lead to HIV treatment failure.…”
Section: Discussionmentioning
confidence: 99%
“… 19 The possible explanation could be that people living with HIV and with TB have confounding factors such as; overlapping drug toxicities, exacerbation of side effects, reduce adherence to prescribed medication, and immune reconstitution inflammatory syndrome. 32 TB weakens the immune system, which in turn facilitates viral replication. 33 HIV-infected patients with opportunistic infection may interrupt the time of taking a drug, lost follow-up, and other triple problems that lead to HIV treatment failure.…”
Section: Discussionmentioning
confidence: 99%
“…O predomínio de casos em pessoas do sexo masculino (76,6%) corroborou achados na literatura. (10)(11)(12)(13)(14)(15)(16)(17)(18)(19) Uma possível causa para o predomínio do sexo masculino refere-se ao aumento da notificação dos casos de aids entre este grupo e a baixa detecção e notificação da aids entre mulheres adultas no período de 2006 a 2017, exceto entre as mulheres idosas. (20) Uma Revisão Sistemática (RS) realizada em países de baixa renda revelou que outra possível razão é que os homens possuem uma prevalência mais alta de TB, pois retardam a procura por atendimento, permanecendo mais tempo infectados em relação às mulheres, o que se reflete no diagnóstico e tratamento oportuno.…”
Section: Discussionunclassified
“…(12,27) Por outro lado, pesquisas apontam o contrário, evidenciando predomínio da raça/cor preta e parda. (10,13,14,19,28,29) Um estudo realizado em São Paulo nos anos de 2006 a 2013, que buscou analisar o perfil epidemiológico dos casos novos de TB, revelou maior incidência de TB em indivíduos indígenas e pretos. (23) Pesquisa realizada com pessoas coinfectadas diagnosticadas entre janeiro de 2008 e julho de 2016 em um serviço de saúde do município do Rio de Janeiro revelou maior atraso da assistência à saúde às pessoas de raça/cor negra ou parda, tanto em relação à busca pelo atendimento quando pela sua demora.…”
Section: Discussionunclassified
See 1 more Smart Citation
“…All of the countries with a TB incidence of more than 500 cases per 100,000 population are in sub-Saharan Africa, although large case numbers have also been found in Asian countries with large populations [ 16 ]. A previous study demonstrated that TB is associated with a high mortality rate when it is diagnosed in the context of virologic failure [ 17 ]. In addition, it was previously shown that having a father as a main caregiver and lack of access to tap water are risk factors for viral failure [ 18 ].…”
Section: Introductionmentioning
confidence: 99%