Assessment of health-related quality of life and related factors in patients with chronic liver disease

Souza, Neila Paula de; Villar, Lívia Melo; Garbín, Artênio José Ísper; Rovida, Tânia Adas Saliba; Garbín, Cléa Adas Saliba

doi:10.1016/j.bjid.2015.08.003

Cited by 29 publications

(30 citation statements)

References 40 publications

(47 reference statements)

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“…MELD‐Na demonstrated a significant negative relationship with role‐emotional following the controlled analysis. Our findings differ from Souza et al, who did not observe a significant relationship between MELD severity and HRQoL . To our knowledge, a relationship between MELD‐NA and role‐emotional has not yet been demonstrated.…”

Section: Resultscontrasting

confidence: 99%

Malnutrition Impacts Health‐Related Quality of Life in Cirrhosis: A Cross‐Sectional Study

et al. 2019

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Background To explore the influence of nourishment state measured by various nutrition assessment tools (NATs) on health‐related quality of life (HRQoL) in a pretransplant population with cirrhosis. Methods We collected demographic, nutrition assessment, and disease specific data on 81 patients. HRQoL was measured with the Short‐Form 36 and divided into 8 subscales. Significant relationships between NATs and HRQoL were examined using independent sample t‐tests, χ2 analyses, correlations, and multiple and logistic regression adjusted for age and gender. Results Study mean age was 54.2 years (SD 10.4 years), and 57% were male. Subjective Global Assessment (SGA) was significantly related to all HRQoL subscales, except bodily pain and mental health. In the adjusted regression models, general health, vitality, and social functioning were all significantly lower in patients with poorer nutrition status measured using SGA (adjusted R2 = 11%, β = −0.34, p < 0.01; adjusted R2 = 8%, β = −0.27, P < 0.05; and adjusted R2 = 12%, β = −0.38, P < 0.01, Q4 respectively). Physical functioning improved as hand grip strength increased (adjusted R2 = 20%, β = 0.36, P < 0.01). MELDNa demonstrated a significant negative relationship with role‐emotional (adjusted R2 = 3%, β = 0.25, P < 0.05), and mid‐arm circumference did not demonstrate any significant relationships with HRQoL. Conclusions Malnutrition assessed by SGA is associated with lower HRQoL in patients with cirrhosis. Future research should identify if nutrition interventions can effectively improve HRQoL in cirrhosis patients.

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Section: Resultscontrasting

confidence: 99%

Malnutrition Impacts Health‐Related Quality of Life in Cirrhosis: A Cross‐Sectional Study

et al. 2019

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“…Hepatitis C infection (HCI) poses a serious threat to the patient and the public health system. Patients with chronic hepatitis face serious long‐term consequences, such as cirrhosis and hepatocellular carcinoma . About 3% of the world's population is exposed to HCI and about 130–150 million people worldwide are registered as HCI virus carriers .…”

Section: Introductionmentioning

confidence: 99%

“…Patients with chronic hepatitis face serious longterm consequences, such as cirrhosis and hepatocellular carcinoma. 1,2 About 3% of the world's population is exposed to HCI and about 130-150 million people worldwide are registered as HCI virus carriers. 3 HCI carries a great burden not only for those who are infected, but also for their caregivers and the wider community, because it is highly contagious and incurs high treatment costs.…”

Section: Introductionmentioning

confidence: 99%

Effect of hepatitis C infection on the quality of life

Horváth

Keleti

Makara

et al. 2018

Perspect Psychiatr Care

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“…The chronic disease is associated with impairments in health-related quality of life (SOUZA et al, 2015). Worldwide, 130-150 million individuals are chronically infected with HCV (WORLD HEALTH ORGANIZATION, 2015).…”

Section: Introductionmentioning

confidence: 99%

A cross sectional study regarding HCV patients’ knowledge about viral transmission and attitudes regarding toothbrush care

Garbín¹,

Souza²,

Moimaz³

et al. 2017

Biosci. J.

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Hepatitis C virus (HCV) is transmitted mainly by parenteral route, although, some studies have pointed the potential of transmission by sharing infected instruments, like toothbrushes. The aim of this study was to investigate the knowledge about viral transmission among HCV infected individuals and attitudes regarding toothbrush care. A cross-sectional study was conducted among 112 HCV-infected individuals from Uberlandia City, Minas Gerais State (Southeast Brazil). Data were collected through a questionnaire containing demographic data and other questions (correct responses were given one point, incorrect and uncertain responses were given zero point) about knowledge of HCV transmission (6 items in total; scores lower than 4 points indicated poor knowledge level and scores equal or higher than 4 indicated good knowledge level); attitudes regarding toothbrush care (7 items; scores 0 to 3 indicated inadequate attitudes, and scores higher than 3 indicated adequate attitudes). The statistical analysis included Chi-square test, Exact Fisher's test and Maximum Likelihood Estimation (p < 0.05 was considered significant). Out of the 112 questionnaires distributed, 85 (response rate: 75.9%) were included. Most individuals were male (60%), Caucasian (69.4%), aged more than 51 years (51.7%), had attended pre-school (35.1%), and had incomes up to $525.2 per month (49.4%). Fifty four percent of individuals showed good Knowledge level of HCV transmission; 43.5% did not identify HCV transmission through toothbrushes and 80% did not believe in HCV transmission by saliva. A significant association were observed between Knowledge level of HCV and age (p= 0.020); and education level (p= 0.000). Forty-five HCV-infected individuals (64.70%) had adequate attitudes regarding toothbrushes care. Significant associations were observed between toothbrush care level and: age (p= 0.005); education level (p= 0.000); and family income (p= 0.038). HCV-infected individuals showed good knowledge level about main aspects of HCV infection and adequate attitudes regarding toothbrush care.

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Assessment of health-related quality of life and related factors in patients with chronic liver disease

Abstract: Most individuals presented high mean Chronic Liver Disease Questionnaire scores, indicating low health-related quality of life, especially individuals with low family income.

Cited by 29 publications

References 40 publications

Malnutrition Impacts Health‐Related Quality of Life in Cirrhosis: A Cross‐Sectional Study

Malnutrition Impacts Health‐Related Quality of Life in Cirrhosis: A Cross‐Sectional Study

Effect of hepatitis C infection on the quality of life

A cross sectional study regarding HCV patients’ knowledge about viral transmission and attitudes regarding toothbrush care

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