A pathognomonic calcification pattern in chronic splenic brucellosis

Torres, Ulysses S.; Cardoso, Luciana Vargas; D'Ippólito, Giuseppe

doi:10.1016/j.bjid.2015.06.003

Cited by 5 publications

(3 citation statements)

References 3 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Hydatid cysts can also resemble some rare calcifications caused by tuberculosis (Azzaza et al, 2020), but this also tends to generate multiple calcifications with a different morphology (Biehler‐Gomez et al, 2020; Gawne‐Cain & Hansell, 1996). The morphology of calcified abscesses observed in rare cases of brucellosis infection is also very distinct, showing a characteristic snowflake shape or, less commonly, a concentric lamellar pattern with central calcification (Colmenero et al, 2002; Karaosmanoglu et al, 2021; Torres et al, 2015). Fungal infections such as histoplamosis or Pneumocystis carinii can also originate calcifications, but these are multiple and smaller (Consul et al, 2020).…”

Section: Discussionmentioning

confidence: 99%

Two cases of cystic echinococcosis reported from al‐Andalus cemeteries (southern Iberia): Insights into zoonotic diseases in Islamic Medieval Europe

López‐Gijón,

Duras,

Maroto‐Benavides

et al. 2023

Intl J of Osteoarchaeology

View full text Add to dashboard Cite

The identification of a calcified hydatid cyst in the bioarcheological record is key to the diagnosis of cystic echinococcosis (i.e., hydatid disease), a parasitic infection caused by the tapeworm Echinococcus granulosus. This zoonosis can be linked to human–canid interactions, given the reproductive cycle of the parasite (from canids to herbivores/humans as intermediate hosts), and it is commonly associated with agropastoral communities in both the past and present. However, it is not easy to identify a calcified hydatid cyst in the archeological record because of preservation problems and its similarity with other calcifications of biological and geological origin. We report the presence of two fragmented ovoidal calcified formations associated with human remains in different medieval Islamic cemeteries from the Kingdom of Granada in al‐Andalus (Southern Iberia, 13th–15th centuries AD). These formations were analyzed by scanning electron microscopy and energy‐dispersive X‐ray spectroscopy. The localization, morphology, and composition of the calcifications indicate that they are hydatid cysts caused by E. granulosus, representing the first evidence of cystic echinococcosis in Islamic Medieval Europe. Our results are in line with archeological and historical records of human–animal interactions and agropastoral practices in al‐Andalus, and they highlight the importance of analyzing calcified masses in the osteoarcheological record.

show abstract

Section: Discussionmentioning

confidence: 99%

Two cases of cystic echinococcosis reported from al‐Andalus cemeteries (southern Iberia): Insights into zoonotic diseases in Islamic Medieval Europe

López‐Gijón,

Duras,

Maroto‐Benavides

et al. 2023

Intl J of Osteoarchaeology

View full text Add to dashboard Cite

show abstract

“…8). Rare cases of splenic infarcts in the course of splenic brucellosis have also been reported [23,24].…”

Section: Brucellosismentioning

confidence: 99%

“…Peripheral or central gross calcifications with a snowflake appearance and less commonly concentric lamellated pattern of splenic calcifications have been described in chronic splenic brucellomas [24]. Serological tests and culture are needed for confirmation, even if clinical history and radiological findings suggest brucellosis.…”

Section: Brucellosismentioning

confidence: 99%

Cross-sectional imaging findings of splenic infections: is differential diagnosis possible?

et al. 2021

View full text Add to dashboard Cite

The spleen plays an important role in the immunological homeostasis of the body. Several neoplastic and non-neoplastic diseases may affect this organ, and imaging is of fundamental importance for diagnosis. Infectious diseases of the spleen can be encountered in daily radiology practice, and differential diagnosis may sometimes be challenging. Infectious involvement of the spleen can be primary or secondary to a different source outside the spleen. Despite the fact that different infectious diseases may cause similar imaging findings, we believe that differential diagnosis between different causes may also be possible in certain patients with imaging. Early diagnosis may potentially enhance patients' treatment and outcome. In this review, we aimed to increase imaging specialists' awareness of splenic infections by describing the multimodality imaging features of common and atypical infections of the spleen with their differential diagnoses.

show abstract

Brucellosis in Patients with Inflammatory Modic Changes: Results from Cross-sectional and Case–Control Comparisons

Alpaycı²

2022

SN Compr. Clin. Med.

View full text Add to dashboard Cite

A pathognomonic calcification pattern in chronic splenic brucellosis

Cited by 5 publications

References 3 publications

Two cases of cystic echinococcosis reported from al‐Andalus cemeteries (southern Iberia): Insights into zoonotic diseases in Islamic Medieval Europe

Two cases of cystic echinococcosis reported from al‐Andalus cemeteries (southern Iberia): Insights into zoonotic diseases in Islamic Medieval Europe

Cross-sectional imaging findings of splenic infections: is differential diagnosis possible?

Brucellosis in Patients with Inflammatory Modic Changes: Results from Cross-sectional and Case–Control Comparisons

Contact Info

Product

Resources

About