Changing the face of fever of unknown origin in Egypt: a single hospital study

Montasser, Mohammed Fawzy; Abdelkader, Nadia Abdelaaty; Montasser, Iman Fawzy; Khouly, Ahmed Mahmoud El

doi:10.1016/j.bjid.2015.02.006

Cited by 8 publications

(10 citation statements)

References 4 publications

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“…Several literature data, especially from developed countries, note the decreasing trend of infections and the rising frequency of NIID as causative factors for FUO during the last decades [4,24]. Despite the decline of infections in the recent times, they still remain a leading category for FUO, especially in community hospitals in developed and in tertiary health care institutions in developing countries [13,18,19,21], as was the case in our study, too. During the last decades, a decreasing trend was noted in malignancies group due to improved diagnostics [7,11,29,30], which was not the case in our material where diagnostic procedures were almost the same as in the previous period.…”

Section: Discussionsupporting

confidence: 73%

“…Namely, in this period, in the political arena the country's external political and inner ethnic issues had higher priority than health care. Comparisons of diagnostic categories of FUO over time were made in few other studies; still, either the studies were conveyed at the same hospital but by different authors [18,19] or they were performed by the same authors but in different institutions [20]. In addition, in some studies the characteristics of FUO were investigated in periods where there was no substantial time difference, i.e.…”

Section: Discussionmentioning

confidence: 99%

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The changing pattern of fever of unknown origin in the Republic of North Macedonia

Bosilkovski

Dimzova

Cvetkova

et al. 2019

Romanian Journal of Internal Medicine

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Introduction. The study aimed to compare the etiologic spectrum of diseases causing fever of unknown origin (FUO) and methods for definitive diagnosis in a tertiary care hospital in the Republic of North Macedonia during two different time periods. Patients and methods. There were analysed retrospectively the causes for FUO and final diagnostic approaches in 185 patients with classic FUO that were treated at the University Hospital for Infectious Diseases in Skopje during two time periods. Seventy nine patients were treated during 1991 to 1995 and 106 patients during 2011 to 2015. Results. When comparing these two periods, infections were present in 46.8% and 29.2% (p = 0.014), non-infective inflammatory disorders in 22.8% and 25.5% (p = 0.674), neoplasms in 10.1% and 13.2% (p = 0.522), miscellaneous in 8.9% and 12.3% (p = 0.461) and undiagnosed cases in 11.4% and 19.8% (p = 0.124), respectively. The most common causes for FUO during the first period were abscesses (8.9%), tuberculosis and systemic lupus erythematosus (7.6% each), whereas in the second period the commonest causes were adult onset Still disease and solid organ neoplasm (7.6% each), polymyalgia rheumatica, abscesses and visceral leishmaniasis (5.7% each). The newer imaging techniques and clinical course evaluation had superior diagnostic significance during the second period. Conclusion. A changing pattern of diseases causing FUO during the examined periods was evident. Infections continue to be the most common cause but with decreasing incidence when compared to 20 years ago. Even nowadays clinical evaluation and follow-up still remain the vital diagnostic tools in determining the etiology of FUO.

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Section: Discussionsupporting

confidence: 73%

Section: Discussionmentioning

confidence: 99%

The changing pattern of fever of unknown origin in the Republic of North Macedonia

Bosilkovski

Dimzova

Cvetkova

et al. 2019

Romanian Journal of Internal Medicine

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“…Besides, the present results as compared with the 374 patients with FUO conducted by Montasser et al (2015) in Egypt showed that infections continue to be the leading cause of FUO (69.7 vs. 66.3%), but the undiagnosed cases dropped from 7.8% to 4.6%. The lower proportion of undiagnosed cases of FUO may be due to advances in diagnostic technologies.…”

Section: Discussionsupporting

confidence: 50%

Epidemiology of Fever of Unknown Origin (Fuo) at Imbaba Fever Hospital, Giza Governorate, Egypt

AlBalakosy

HUSSEIN

KHALIL³

et al. 2022

Journal of the Egyptian Society of Parasitology

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Fever of unknown origin (FUO) is caused by various diseases, and infections were the most frequent causes of FUO. The progress of the diagnostic techniques may have changed the breakdown of diseases causing FUO. This prospective study aimed to explore the clinical spectrum of fevers of undetermined origin (FUO) among adult patients treated at the Imbaba Fever Hospital from June 2018 to May 2019.All Egyptian patients who met the FUO criteria and were hospitalized during this period were followed up until they were diagnosed. They were 350 of whom186 females (53.1%) and 164 males (46.9%), with ages ranged from 18 to 82 years (32.77±14.4). The commonest FUO cause was infections (72%), followed by autoimmune diseases (20%), malignancies accounted (2%) of the total with the diagnosis unknown in 4.6%. Brucellosis and pneumonia were considered major causes of infections.

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“…Owing to high costs, no specific investigational flow protocol for the diagnosis of FUO in Egypt is followed. Only initial investigations are done, together with the history and clinical findings that may guide the diagnosis [20].. Lab findings among the studied group in the present work ( Figure 2) revealed that about 72.7% of the studied participants had positive CRP.…”

Section: Discussionmentioning

confidence: 50%

Highlighting the Role of Infections in the Etiology of Fever of Unknown Origin Pointing out Toxoplasmosis; in Port Said Governorate

Arnous

Elgammal

Mostafa

et al. 2020

Afro-Egyptian Journal of Infectious and Endemic Diseases

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Changing the face of fever of unknown origin in Egypt: a single hospital study

Cited by 8 publications

References 4 publications

The changing pattern of fever of unknown origin in the Republic of North Macedonia

The changing pattern of fever of unknown origin in the Republic of North Macedonia

Epidemiology of Fever of Unknown Origin (Fuo) at Imbaba Fever Hospital, Giza Governorate, Egypt

Highlighting the Role of Infections in the Etiology of Fever of Unknown Origin Pointing out Toxoplasmosis; in Port Said Governorate

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