Orf disease: a report of a case

Koufakis, Theocharis; Katsaitis, Periklis; Gabranis, Ioannis

doi:10.1016/j.bjid.2014.04.001

Cited by 9 publications

(7 citation statements)

References 4 publications

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“…However, multiple lesions have also been described in the medical literature [6]. The diagnosis of orf is usually made based on its clinical features and the exposure history of the patient [7]. In suspicious cases, a skin biopsy and polymerase chain reaction may be performed [8].…”

Section: Discussionmentioning

confidence: 99%

The spectacular presentation of orf disease

Tamer¹,

Yüksel²

2018

Our Dermatol Online

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Orf is a viral zoonotic skin disorder which is also called ecthyma contagiosum. The disease primarily affects sheep and goats, however it can be transmitted to humans through close contact with infected animals. Orf presents with characteristic skin lesions and the diagnosis of orf is usually made based on its clinical features. Hereby, we present a 21-year-old female patient with orf disease with a characteristic clinical lesion on her hand.

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Section: Discussionmentioning

confidence: 99%

The spectacular presentation of orf disease

Tamer¹,

Yüksel²

2018

Our Dermatol Online

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“…For the treatment of uncomplicated orf infection, local antiseptic dressing is recommended in order to prevent secondary bacterial infections. Cidofovir cream and cryotherapy have recently been used successfully to treat very large lesions [ 1 , 4 , 6 ]. In our case, systemic steroid and hydroxyzine were used to treat erythema multiforme and bullous pemphigoid-like eruptions.…”

Section: Discussionmentioning

confidence: 99%

A Case of Orf Disease Complicated with Erythema Multiforme and Bullous Pemphigoid-Like Eruptions

Alian

Ahangarkani

Arabsheybani

2015

Case Reports in Infectious Diseases

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Parapoxvirus infection in sheep and goats is usually referred to as contagious pustular dermatitis/ecthyma, or orf, and the corresponding human infection is referred to as orf. In humans, after a brief incubation period of 3 to 5 days, lesions begin as pruritic erythematous macules and then rise to form papules, often with a target appearance. Lesions become nodular or vesicular, and orf lesions often ulcerate after 14 to 21 days. Erythema multiforme and bullous pemphigoid have been associated with parapoxvirus infections and they are rare complications of orf disease. In this case report, we presented a 36-year-old woman with history of contact with sheep, developing a typical orf lesion that is complicated with erythema multiforme and bullous pemphigoid-like eruptions.

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“…Small ruminants have a tremendous importance in terms of generating income in the form of meat, wool, hide and occasionally milk in small scale farming. However, infectious diseases are still the health challenges by hindering the production and productivity and this causes huge economic loss [ 1 , 2 ]. Contagious ecthyma or alternatively called contagious pustular dermatitis is a viral disease of sheep and goat caused by Orf virus which belongs to the family of poxviridae and based on the classification of international committee on taxonomy of viruses(ICTV), it is one of the notifiable viral disease known to have a zoonotic importance [ 1 , 3 , 4 ].…”

Section: Introductionmentioning

confidence: 99%

Molecular identification and investigations of contagious ecthyma (Orf virus) in small ruminants, North west Ethiopia

et al. 2018

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BackgroundOrf virus, the prototype of parapoxvirus, is the main causative agent of contagious ecthyma. Little is known about the status of the disease in Ethiopia and this study was aimed at determining its status using PCR as a confirmatory tool.Methodsa total of 400 randomly selected sheep and goat was screened for the identification of the virus using amplification of B2L gene and transfection of mammalian cells (VERO cells).ResultsOut of 400 animals screened for infection of the virus, 48 animals were found positive to PCR and revealed an overall incidence of 12%. Different epidemiological parameters were considered to look at the association with incidence of the disease and of which, only species of the animal(sheep), non-vaccinated and non-treated animals, nursing animals, poor body condition animals, extensively managed animals, animals having mouth lesion, and study areas having outbreak history showed higher prevalence. A univariate logistic regression analysis showed statistically significant difference in all variables (P < 0.05). Whereas, age and sex of animals showed no significant difference (P < 0.05).ConclusionThe result of the present finding showed high incidence of Orf virus in the region as confirmed through PCR.

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Orf disease: a report of a case

Cited by 9 publications

References 4 publications

The spectacular presentation of orf disease

The spectacular presentation of orf disease

A Case of Orf Disease Complicated with Erythema Multiforme and Bullous Pemphigoid-Like Eruptions

Molecular identification and investigations of contagious ecthyma (Orf virus) in small ruminants, North west Ethiopia

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