Hand, foot, and mouth disease in an adult

Akkoyunlu, Yasemin; Ceylan, Bahadır; Aslan, Turan

doi:10.1016/j.bjid.2013.11.004

Cited by 2 publications

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“…Hastaların hastalığın şiddetini gösteren klinik ve laboratuvar bulgular açısından ayrıntılı değerlendirilmesi gereklidir. yaptıkları araştırmalar ve birkaç olgu sunumu dışında yeterli sayıda çalışma bulunmamaktadır 10,11 . Çalışmamızın amacı; hastanemize ateş ve döküntü şikayeti ile başvurup, klinik bulgulara dayanılarak EAAH tanısı koyulan hastaların prospektif izlemlerini ve deneyimlerimizi paylaşmaktır.…”

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Joint diagnosis of pediatric and dermatology clinics: Prospective observation of thirtynine patients with hand, foot and mouth disease

Bucak¹,

Tepe²,

Almış³

et al. 2017

TURKDERM

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Background and Design: Hand, foot and mouth disease (HFMD) is a childhood enteroviral eruptive disease presenting with fever and cutaneous and mucosal lesions. It is benign and generally resolves spontaneously, but may sometimes result in systemic involvement. The purpose of this study was to share our clinical experience concerning patients who were followed with the diagnosis of HFMD established by the pediatric and dermatology clinics. Materials and Methods: We prospectively evaluated patients who attended our hospital with the complaints of fever and eruptions and received the diagnosis of HFMD based on the clinical findings between December 2014 and November 2015. Age, sex, month of presentation, presentation symptoms and duration of symptoms were investigated. Systemic and dermatological examination findings, laboratory results and tests such as echocardiography were reviewed. Results: Thirty-nine patients were included; 19 (48.8%) were girl and 20 (51.2%) were boy. The mean age of the patients was 29.8±27.9 (6-155) months. Six (15.3%) patients were in the 0-12 month age group, while only 3 (7.8%) were older than 60 months. Presentations were most common in September, June and October. The most common presentation symptoms were eruptions on the hands and feet (100%), fever (82.1%) and oral aphthae (79.5%). The lesions were most commonly observed on the hands (94.9%, n=37) and feet (87.2%, n=34) and in the mouth (79.5%, n=31). Cardiac involvement was determined in 3 (7.7%) patients. Nail changes were observed during monitoring in 10 (25.6%) patients. AbstractAmaç: El-ayak-ağız hastalığı (EAAH); ateş, deri ve mukoza lezyonları ile seyreden, çocukluk çağının enteroviral döküntülü bir hastalığıdır. İyi seyirli ve kendiliğinden düzelme eğiliminde olmakla birlikte, nadiren sistemik tutuluma yol açabilir. Bu çalışmanın amacı, pediatri ve dermatoloji klinikleri tarafından EAAH tanısıyla takip edilen hastalara ait klinik deneyimlerimizi paylaşmaktır. Gereç ve Yöntem: Hastanemize Aralık 2014-Kasım 2015 tarihleri arasında ateş ve döküntü şikayeti ile başvuran hastalardan, klinik bulgulara dayanılarak EAAH tanısı koyulan hastalar prospektif olarak değerlendirildi. Hastaların yaşı, cinsiyeti, başvuru ayı, başvuru şikayeti ve süresi sorgulandı. Sistemik ve dermatolojik muayene bulguları, laboratuvar sonuçları, ekokardiyografi gibi ek inceleme tetkikleri gözden geçirildi. Bulgular: Çalışmaya toplam 39 hasta dahil edildi. Hastaların 19'u (%48,8) kız, 20'si (%51,2) erkek idi. Hastaların ortalama yaşı 29,8±27,9 (6-155) ay olarak hesaplandı. Yaş aralığına göre hastaların 6'sı (%15,3) 0-12 ay arasında iken, sadece 3'ü (%7,8) 60 aydan büyüktü. Başvurular en sık Eylül, Haziran ve Ekim aylarında görüldü. En sık başvuru şikayeti; el ve ayaklarda döküntü (%100), ateş (%82,1) ve oral aft (%79,5) idi. Lezyonlar, en sık el (%94,9, n=37), ayak (%87,2, n=34) ve ağız içinde (%79,5, n=31) görüldü. Üç hastada (%7,7) kardiyak tutulum saptandı. Takiplerde 10 hastada (%25,6) tırnak değişikliği gelişti. Sonuç: Çalışmamız sonucunda ülkemizde E...

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Joint diagnosis of pediatric and dermatology clinics: Prospective observation of thirtynine patients with hand, foot and mouth disease

Bucak¹,

Tepe²,

Almış³

et al. 2017

TURKDERM

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“…CA6 emerged as a large scale outbreak in Thailand in 2012 and continued to be one of the major causes of HFMD worldwide (Wei et al 2011 ; Flett et al 2012 ; Fujimoto et al 2012 ; Chung et al 2013 ; Kaminska et al 2013 ; Lott et al 2013 ; Ben-Chetrit et al 2014 ; Feder et al 2014 ; Hubiche et al 2014 ; Li et al 2014 ; Sinclair et al 2014 ). Unusual manifestations include widespread vesiculobullous and erosive lesions extending beyond the palms and soles (Wei et al 2011 ; Chung et al 2013 ; Kobayashi et al 2013 ; Lott et al 2013 ; Mathes et al 2013 ; Feder et al 2014 ; Hubiche et al 2014 ) including dorsal sides of the hands and feet (Flett et al 2012 ; Feder et al 2014 ), calves and trunk (Feder et al 2014 ), eczema herpeticum-like eruption termed “eczema coxsackium” (Mathes et al 2013 ; Akkoyunlu et al 2014 ; Sinclair et al 2014 ), eruption similar to GCS (Mathes et al 2013 ), petechiae or purpuric eruption (Mathes et al 2013 ; Stewart et al 2013 ), varicelliform (Yasui et al 2013 ; Sinclair et al 2014 ), delayed desquamation of palms and soles (Wei et al 2011 ; Mathes et al 2013 ), and onychomadesis (transient separation of proximal nail plate) during convalescence (Wei et al 2011 ; Feder et al 2014 ).…”

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confidence: 99%

Unusual skin manifestation of hand, foot and mouth disease associated with coxsackievirus A6: cases report

et al. 2015

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BackgroundHand, food, and mouth disease (HFMD) is a highly contagious disease caused by enteroviruses infection. It is a health problem in young children under 5 years of age worldwide. The common causative agents are coxsackievirus A 16 (CA16) and enterovirus 71 (EV71). In recent years, coxsackievirus A6 (CA6) has emerged to be one of the major etiologic agents of HFMD worldwide including in Thailand.Case descriptionWe reported cases with unusual skin manifestations of CA6-associated HFMD such as widespread severe cutaneous eruption, large vesicles (varicelliform), purpuric-like lesions or Gianotti–Crosti like eruptions.Discussion and evaluationMolecular characterization of the CA6 strains from those patients found that all were clustered in the same group of CA6 that are currently circulating in Thailand.ConclusionsClinicians need to be aware of the expanded range of cutaneous findings in CA6-associated HFMD in order to properly consider the diagnosis, management and prevention.

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Hand, foot, and mouth disease in an adult

Cited by 2 publications

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Joint diagnosis of pediatric and dermatology clinics: Prospective observation of thirtynine patients with hand, foot and mouth disease

Joint diagnosis of pediatric and dermatology clinics: Prospective observation of thirtynine patients with hand, foot and mouth disease

Unusual skin manifestation of hand, foot and mouth disease associated with coxsackievirus A6: cases report

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