Nosocomial infections caused by Elizabethkingia meningoseptica: an emergent pathogen

Pereira, Graziella Hanna; Garcia, Doroti de Oliveira; Abboud, Cely Saad; Barbosa, Vera Lúcia; Silva, Paulo Sérgio Lucas da

doi:10.1016/j.bjid.2013.02.011

Cited by 33 publications

(38 citation statements)

References 14 publications

(26 reference statements)

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“…Vancomycin has been previously recommended as the drug of choice for the treatment of neonatal meningitis due to E. meningoseptica . [16] However, the high MICs (16 μg/mL) of vancomycin for the organisms as demonstrated in our study as well as those of others[18] first indicate that vancomycin should not be considered the drug of choice. On the contrary, this study confirms the better activity of ciprofloxacin against E. meningoseptica infection, as has been seen in other studies.…”

Section: Discussionsupporting

confidence: 49%

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Elizabethkingia meningoseptica : Emerging nosocomial pathogen in bedside hemodialysis patients

Ratnamani

Rao

2013

Indian Journal of Critical Care Medicine

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Elizabethkingia meningoseptica, a ubiquitous gram-negative aerobic bacillus, is an emerging hospital acquired pathogen in patients on dialysis. It has been isolated in the hospital environment in water supplies, disinfectants, and medical devices. We present here an analysis of eight healthcare-acquired infections with this organism in adults. To the best of our our knowledge, this is the first report of infections with this organism in patients on hemodialysis.Materials and Methods:Over a 6-month period, eight patients were infected with E. meningoseptica in our hospital. These patients had bacteremia and lower respiratory tract infection. All these patients were on on mechanical ventilation and undergoing bedside hemodialysis in the intensive care unit (ICU). Environmental surveillance was done to detect the possible source.Results:These patients had a common denominator of bedside hemodialysis, and use of broad-spectrum antibiotics. E. meningoseptica was isolated from the water and sink of the ICU.Conclusion:E. meningoseptica is emerging as a nosocomial pathogen among patients on hemodialysis. Its unusual resistance pattern coupled with inherent resistance to colistin makes this organism difficult to treat unless susceptibility patterns are available. Isolation of this organism in handwash sink and water is a significant finding as they have been reported to survive in chlorinated water. Disinfecting the sinks and using filtered water for hand washing in critical areas may help in preventing infections with this organism.

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Section: Discussionsupporting

confidence: 49%

“…As compared to other studies where E. meningoseptica was a late infection, approximately after 50-70 days after admission to hospital,[16] in our study, the time interval between the admission of a patient to hospital and infection with E. meningoseptica was an average of 5 days (3-7 days).…”

Section: Discussionsupporting

confidence: 47%

Elizabethkingia meningoseptica : Emerging nosocomial pathogen in bedside hemodialysis patients

Ratnamani

Rao

2013

Indian Journal of Critical Care Medicine

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“…The Carnobacterium OTU (phylum Firmicutes) is a lactic acid bacterium with putative probiotic properties providing protection against various bacterial pathogens [94,95]. On the other hand, Chryseobacterium and Elizabethkingia OTUs (both from the family Flavobacteriaceae) are related to several pathogenic species of human and other vertebrate taxa [96–98]. …”

Section: Discussionmentioning

confidence: 99%

Variation between the oral and faecal microbiota in a free-living passerine bird, the great tit (Parus major)

et al. 2017

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The gastrointestinal tract of vertebrates is inhabited by diverse bacterial communities that induce marked effects on the host physiology and health status. The composition of the gastrointestinal microbiota is characterized by pronounced taxonomic and functional variability among different regions of the vertebrate gastrointestinal tract. Despite the relatively solid knowledge on the among-region variations of the gastrointestinal microbiota in model mammalian species, there are only a few studies concerning among-region variations of the gastrointestinal microbiota in free-living non-mammalian vertebrate taxa. We used Illumina MiSeq sequencing of bacterial 16S rRNA amplicons to compare the diversity as well as taxonomic composition of bacterial communities in proximal vs. distal parts of the gastrointestinal tract (represented by oral swabs and faecal samples, respectively) in a wild passerine bird, the great tit (Parus major). The diversity of the oral microbiota was significantly higher compared to the faecal microbiota, whereas interindividual variation was higher in faecal than in oral samples. We also observed a pronounced difference in taxonomic content between the oral and faecal microbiota. Bacteria belonging to the phyla Proteobacteria, Firmicutes and Actinobacteria typically dominated in both oral and faecal samples. A high abundance of bacteria belonging to Tenericutes was observed only in faecal samples. Surprisingly, we found only a slight correlation between the faecal and oral microbiota at the within-individual level, suggesting that the microbial composition in these body sites is shaped by independent regulatory processes. Given the independence of these two communities at the individual level, we propose that simultaneous sampling of the faecal and oral microbiota will extend our understanding of host vs. microbiota interactions in wild populations.

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“…Although some studies, such as those carried out by Echeverri et al (2) , Krebs et al (6) , and Pereira et al (9) demonstrated that the antimicrobial trimethoprim-sulfamethoxazole, rifampin, and vancomycin are useful in clinical practice for treating E. meningoseptica infections, they were not tested in this study because …”

Section: Casementioning

confidence: 98%

“…Also in São Paulo-Brazil, Pereira et al (9) described clinical and epidemiological study of nine patients, two with neutropenia, admitted to two tertiary care teaching hospitals for two years, the deaths occurred in 33% of them, predominantly with pneumonia, the treatment regimen for E. meningoseptica was vancomycin.…”

Section: Casementioning

confidence: 99%

Infection by multidrug-resistant Elizabethkingia meningoseptica: case reports

Lima¹,

Albuquerque

Alves³

et al. 2014

Jornal Brasileiro De Patologia E Medicina Laboratorial

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Nosocomial infections caused by Elizabethkingia meningoseptica: an emergent pathogen

Cited by 33 publications

References 14 publications

Elizabethkingia meningoseptica : Emerging nosocomial pathogen in bedside hemodialysis patients

Elizabethkingia meningoseptica : Emerging nosocomial pathogen in bedside hemodialysis patients

Variation between the oral and faecal microbiota in a free-living passerine bird, the great tit (Parus major)

Infection by multidrug-resistant Elizabethkingia meningoseptica: case reports

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