A case of miltefosine responsive pleomorphic post kala-azar dermal leishmaniasis

Pal, Dipankar; Naskar, Arindam; Ghosh, Manab Kumar

doi:10.1016/j.bjid.2012.12.011

Cited by 3 publications

(4 citation statements)

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“…Moreover, pleomorphic PKDL with macules, papules and nodules in different parts of body in the same patient is also very rare. Pal et al in their case report has demonstrated such a case which was responsive to standard dose of miltefosine [4].…”

Section: Discussionmentioning

confidence: 89%

A Case of Pleomorphic Post Kala-azar Dermal Leishmaniasis without History of Visceral Leishmanniasis

Pal¹,

Gupta²,

Das³

et al. 2015

Trop Med Surg

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Section: Discussionmentioning

confidence: 89%

A Case of Pleomorphic Post Kala-azar Dermal Leishmaniasis without History of Visceral Leishmanniasis

Pal¹,

Gupta²,

Das³

et al. 2015

Trop Med Surg

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“…Only two such cases have been reported from India but none from Nepal. 4,5 On the basis of earlier observations in Bangladesh, the proportion of such cases clinically diagnosed among all PKDL was ∼9%. The incidence of PKDL among cured VL patients is postulated to be 10-17% within 5 years.…”

Section: Discussionmentioning

confidence: 99%

“…Although PKDL mainly occurs after VL treatment, some exclusive cases have been reported to occur in patients without a previous history of VL. [4][5][6][7] The identification, confirmation and treatment of such cases were insufficiently described in these reports. Herein, we discuss three parasitologically confirmed cases which were successfully cured after miltefosine treatment.…”

Section: Introductionmentioning

confidence: 99%

Post-Kala-Azar Dermal Leishmaniasis Without Previous History of Visceral Leishmaniasis

Hasnain

Shomik

Ghosh

et al. 2016

The American Society of Tropical Medicine and Hygiene

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“…Miltefosine was also used to successfully treat a pleomorphic PKDL in an Indian patient hailing from Bihar (Pal et al, 2013).…”

Section: Ajidmentioning

confidence: 99%

Post Kala-Azar Dermal Leishmaniasis With Ulceration on Foot: An Atypical Case Presentation Successfully Treated With Miltefosine

Das¹

2014

American Journal of Infectious Diseases

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Visceral Leishmaniasis (VL) or Kala-Azar (KA) is highly endemic in the Indian subcontinent particularly in Bihar. Post Kala-azar Dermal Leishmaniasis (PKDL) is a known reservoir for leishmania parasites for transmission of VL. The kala-azar elimination program was launched by the government of three countries of the Indian subcontinent in the year 2005, which aims to eliminate kala-azar by 2015 and PKDL by 2018. PKDL diagnosis and management has not been addressed properly. In this case report we have described a case of PKDL with ulcer and atypical presentation who was subsequently diagnosed by demonstration of Leishmania donovani bodies in the skin snips through microscopy, kinetoplast-DNA nested PCR and clinically. The patient was treated with miltefosine capsules in the dose of 50 mg twicea-day for twelve-weeks and responded completely. This case report assumes great importance as prompt diagnosis and treatment of PKDL is essential in the kala-azar elimination program.

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A case of miltefosine responsive pleomorphic post kala-azar dermal leishmaniasis

Cited by 3 publications

References 0 publications

A Case of Pleomorphic Post Kala-azar Dermal Leishmaniasis without History of Visceral Leishmanniasis

A Case of Pleomorphic Post Kala-azar Dermal Leishmaniasis without History of Visceral Leishmanniasis

Post-Kala-Azar Dermal Leishmaniasis Without Previous History of Visceral Leishmaniasis

Post Kala-Azar Dermal Leishmaniasis With Ulceration on Foot: An Atypical Case Presentation Successfully Treated With Miltefosine

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