Erratum to “Frequencies of polymorphisms of Rh, Kell, Kidd, Duffy and Diego systems of Santa Catarina, southern Brazil” [Rev Bras Hematol Hemoter. 2016;38(3):199–205]
“…In our study, the frequency of the RHCE*Cc genotype was higher, when compared to the populations of the studies from Santa Catarina and Paraná, 6 , 9 , 14 which is also different from the study carried out in the southeast (Minas Gerais) and the study in the northeast (Bahia) 6 , 15 ; in these populations, the most frequent genotype was the RHCE*cc . There is a high prevalence of the RHCE*cc in Afro-descendants, 19 which can be explained by the southeast and northeast of the country having the greatest African presence.…”
Section: Discussioncontrasting
confidence: 99%
“… a p < 0.05 b p < 0.01 c p < 0.001 with Chi-square test or Fisher's exact test, compared in our study. POP-SC: Blood donors in Santa Catarina, 6 , 14 POP-PR: Blood donors in Paraná, 9 POP-SP: Blood donors in São Paulo, 10 , POP-MG: Blood donors in Minas Gerais, 15 POP-BA: Admixed population in Bahia. 6 …”
Section: Resultsmentioning
confidence: 99%
“…POP-RS: Blood donors in Porto Alegre, Rio Grande do Sul. 12 POP-SC: Blood donors in Santa Catarina, 6 , 14 POP-PR: Blood donors in Paraná, southern Brazil, 9 POP-SP: Blood donors in São Paulo, 10 POP-MG: Blood donors in Minas Gerais, 15 POP-BA: Admixed population in Bahia. 6 , 10 …”
Section: Resultsmentioning
confidence: 99%
“……”
Section: Resultsmentioning
confidence: 99%
“…The Chi-square test (χ 2 ), or Fisher's exact test, was used to determine the differences between genotypic and allelic frequencies in the present study and data from populations (POPs) in other regions of Brazil: POP-Porto Alegre (RS) 12 ; POP-Santa Catarina (SC) 6 , 14 ; POP-Paraná (PR) 9 ; POP-São Paulo (SP) 10 ; POP-Minas Gerais (MG) 15 ; and; POP-Bahia (BA). 6 , 14 A p -value < 0.05 was considered significant and comparisons were performed using the Winpepi version 11.65 software. 16 The Arlequin computer version 3.5.2.2, available at ( http://cmpg.unibe.ch/software/arlequin35/ ), was used to test the Hardy-Weinberg equilibrium.…”
“…In our study, the frequency of the RHCE*Cc genotype was higher, when compared to the populations of the studies from Santa Catarina and Paraná, 6 , 9 , 14 which is also different from the study carried out in the southeast (Minas Gerais) and the study in the northeast (Bahia) 6 , 15 ; in these populations, the most frequent genotype was the RHCE*cc . There is a high prevalence of the RHCE*cc in Afro-descendants, 19 which can be explained by the southeast and northeast of the country having the greatest African presence.…”
Section: Discussioncontrasting
confidence: 99%
“… a p < 0.05 b p < 0.01 c p < 0.001 with Chi-square test or Fisher's exact test, compared in our study. POP-SC: Blood donors in Santa Catarina, 6 , 14 POP-PR: Blood donors in Paraná, 9 POP-SP: Blood donors in São Paulo, 10 , POP-MG: Blood donors in Minas Gerais, 15 POP-BA: Admixed population in Bahia. 6 …”
Section: Resultsmentioning
confidence: 99%
“…POP-RS: Blood donors in Porto Alegre, Rio Grande do Sul. 12 POP-SC: Blood donors in Santa Catarina, 6 , 14 POP-PR: Blood donors in Paraná, southern Brazil, 9 POP-SP: Blood donors in São Paulo, 10 POP-MG: Blood donors in Minas Gerais, 15 POP-BA: Admixed population in Bahia. 6 , 10 …”
Section: Resultsmentioning
confidence: 99%
“……”
Section: Resultsmentioning
confidence: 99%
“…The Chi-square test (χ 2 ), or Fisher's exact test, was used to determine the differences between genotypic and allelic frequencies in the present study and data from populations (POPs) in other regions of Brazil: POP-Porto Alegre (RS) 12 ; POP-Santa Catarina (SC) 6 , 14 ; POP-Paraná (PR) 9 ; POP-São Paulo (SP) 10 ; POP-Minas Gerais (MG) 15 ; and; POP-Bahia (BA). 6 , 14 A p -value < 0.05 was considered significant and comparisons were performed using the Winpepi version 11.65 software. 16 The Arlequin computer version 3.5.2.2, available at ( http://cmpg.unibe.ch/software/arlequin35/ ), was used to test the Hardy-Weinberg equilibrium.…”
We evaluated genetic variability among the blood groups Kell (c.578C > T and c.1790T > C), Kidd (c.838A > G), Duffy (c.125A > G, c.265C > T and c.1-67T > C), Diego (c.2561C > T), MNS (c.143T > C) and Rh (c.676G > C) in Rio Grande do Sul in southern Brazil. Genetic profiling from 382 volunteer blood donors was performed through allelic discrimination assays using a hydrolysis probe (TaqMan®) with a real-time PCR system. The sample was divided into two groups: Euro-Brazilian and Afro-Brazilian. A comparison with studies from other regions of Brazil and the 1000 Genomes Database showed significant differences for almost all polymorphisms evaluated in our population. Population differentiation between the Euro-and Afro-Brazilian groups was low (F ST value 0.055). However, when each locus was evaluated individually, KEL*06 and FY*02N.01 allele frequencies were significantly higher in the Afro-Brazilian group than in the Euro-Brazilian group. Ethnic classification that uses phenotypic criteria to find blood units with rare antigens may be important when there is a need to detect blood units with an absence of Duffy antigens. There is also a greater probability of finding donors in the Afro-Brazilian group. Taken together, the data indicate strong European and African contributions to the gene pool, with intense admixture.
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