Postoperative analgesia efficacy of erector spinae plane block in patients submitted to cardiac surgery: randomized clinical trial

Silv, Larissa Martins; Brandão, Amanda Jiran Ferreira Marcos; Godo, Jhonson Tizzo; Leã, Wirleyde Mattos; Freitas, Juliana Faria de; Fernande, Magda Lourenço

doi:10.1016/j.bjane.2022.06.006

Cited by 1 publication

(3 citation statements)

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“…Finally, we included 16 studies which included 1110 patients for analysis (489 in ESPB and 621 in control), [ Figure 1 ]. [ 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 ] Table 1 summarizes the details of all the studies included in the analysis.…”

Section: Resultsmentioning

confidence: 99%

“…Eight studies reported 24-hr morphine consumption[ 14 15 16 17 18 19 20 21 ] and 5 studies[ 22 23 24 25 26 ] reported 48-hr opioid consumption. For 24-hr morphine consumption, there were 232 patients in ESPB group and 240 patients in the control group.…”

Section: Resultsmentioning

confidence: 99%

“…For 0 hour, pain scores were reported by 7 studies (ESPB-193, control-220),[ 16 17 19 21 27 ] at 1 hour by 5 studies(ESPB-160, control-158),[ 16 17 19 21 27 ] at 2 hours by 5 studies (ESPB-228, control-226),[ 14 15 16 17 19 21 27 ] at 4 hours by 7 studies (ESPB-248, control-246),[ 14 15 16 17 19 21 27 ] at 6 hours by 6 studies (ESPB-178, control-182),[ 16 17 19 21 27 ] at 8 hours by 7 studies (ESPB-233, control-231),[ 14 15 16 17 19 21 27 ] at 10 hours by 3 studies (ESPB-118, control-118),[ 14 17 27 ] at 12 hours by 8 studies (ESPB-248, control-246),[ 14 15 16 17 19 21 25 27 ] at 16 hours by 4 studies (ESPB-120, control-118),[ 17 18 20 22 ] and at 24 hours by 6 studies (ESPB-155, control-153). [ 15 16 17 19 21 25 ] [ Figure 5 ]…”

Section: Resultsmentioning

confidence: 99%

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Erector Spinae Plane Block for Postoperative Analgesia in Cardiac Surgeries- A Systematic Review and Meta-Analysis

Nair

Saxena

Borkar

et al. 2023

Annals of Cardiac Anaesthesia

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Ultrasound-guided erector spinae plane block (ESPB) has been used in many studies for providing opioid-sparing analgesia after various cardiac surgeries. We performed a systematic review and meta-analysis of randomized controlled trials to assess the efficacy of ESPB in cardiac surgeries. We searched PubMed, Embase, Cochrane Central Register of Controlled Trials (CENTRAL), and Google Scholar to identify the studies in which ESPB was compared with the control group/sham block in patients undergoing cardiac surgeries. The primary outcomes were postoperative opioid consumption and postoperative pain scores. The secondary outcomes were intraoperative opioid consumption, ventilation time, time to the first mobilization, length of ICU and hospital stay, and adverse events. Out of 607 studies identified, 16 studies (n = 1110 patients) fulfilled inclusion criteria and were used for qualitative and quantitative analysis. Although, 24-hr opioid consumption were comparable in both groups group (MD, −18.74; 95% CI, −46.85 to 9.36, P = 0.16), the 48-hr opioid consumption was significantly less in ESPB group than control ((MD, −11.01; 95% CI, −19.98 to −−2.04, P = 0.02). The pain scores at various time intervals and intraoperative opioid consumption were significantly less in ESPB group. Moreover, duration of ventilation, time to the first mobilization, and length of ICU and hospital were also less in ESPB group (P < 0.00001, P < 0.00001, P < 0.00001, and P < 0.0001, respectively). This systematic review and meta-analysis demonstrated that ESPB provides opioid-sparing perioperative analgesia, facilitates early extubation and mobilization, leads to early discharge from ICU and hospital, and has lesser pruritus when compared to control in patients undergoing cardiac surgeries.

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