Successful use of sugammadex for caesarean section in a patient with myasthenia gravis

Soyoral, Lokman; Göktaş, Uğur; Çeğin, Muhammed Bilal; Baydi, Volkan

doi:10.1016/j.bjane.2014.08.008

Cited by 6 publications

(5 citation statements)

References 5 publications

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“…Therefore, many studies and case presentations have reported that an adequate muscle relaxation can only be achieved by inhalation agents. However, upon the availability of sugammadex, results indicate safe use of rocuronium in this group of patients [15,16].…”

Section: Discussionmentioning

confidence: 98%

Retrospective evaluation of anaesthesia methods in pregnant women with neurological and neuromuscular syndromes who underwent caesarean section

Sargın¹,

Cağıran²,

Biliç³

et al. 2017

Clin. Exp. Obstet. Gynecol.

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The purpose of this study was to investigate the anaesthesia methods used in pregnant women with neurological or neuromuscular disease who underwent caesarean section. Materials and Methods: Demographics; pregnancy weeks, urgent or elective caesarean section, accompanying neurological or neuromuscular diseases, and anaesthesia type. Results: Of the pregnant women operated on, 72% (16),14% (three) and 14% (three) were diagnosed with epilepsy, multiple sclerosis (MS), and myasthenia gravis (MG), respectively. General anaesthesia was administered in 45%, 40%, and 25% of epileptic pregnant women, patients with MS, and those diagnosed with MG, respectively. Spinal anaesthesia was administered in 55%, 20%, and 75% of epileptic pregnant women, those with MS, and those diagnosed with MG, respectively. Conclusion: Regional anaesthesia may be an appropriate option in pregnant women with neurological or neuromuscular diseases. Epidural anaesthesia may be a safer method in terms of ensuring the control of block level.

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Section: Discussionmentioning

confidence: 98%

Retrospective evaluation of anaesthesia methods in pregnant women with neurological and neuromuscular syndromes who underwent caesarean section

Sargın¹,

Cağıran²,

Biliç³

et al. 2017

Clin. Exp. Obstet. Gynecol.

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“…In patients with severe disease who are at higher risk of recurrent exacerbation during pregnancy, adjunct steroids and rituximab maybe started during their ICU course if prolonged hospitalization is expected and maternal benefit outweighs the risk. Steroids are associated with small (<1%) risk of cleft palate and rituximab with transient decline in B-cell counts, though data is very limited for rituximab and is generally not recommended [ 68 , 71 ].…”

Section: Medical and Surgical Managementmentioning

confidence: 99%

“…Pre-eclampsia (PE) presents a unique challenge in this population as magnesium, the treatments of choice for seizure prophylaxis in PE, is contraindicated in MG [ 71 , 73 ]. Thus, levetiracetam, valproic acid, and diazepam have all been used for seizure prophylaxis in these mothers.…”

Section: Medical and Surgical Managementmentioning

confidence: 99%

Neurocritical Care of the Pregnant Patient

Malaiyandi

James

Peglar

et al. 2021

Curr Treat Options Neurol

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Purpose of review To summarize recent changes in management and emerging therapies for pregnant neurocritical care patients. Recent findings Diagnostic and treatment options for managing neurologic emergencies in pregnant patients have expanded with both greater understanding of the effects of imaging modalities and medications on pregnancy and application of standard treatments for non-pregnant patients to pregnant populations. Specifically, this includes cerebrovascular diseases (pregnancy-associated ischemic stroke, pregnancy-associated intracerebral hemorrhage, cerebral venous sinus thrombosis), post-maternal cardiac arrest care, seizures and status epilepticus, myasthenia gravis, and fetal somatic support in maternal death by neurologic criteria. Summary With the exception of direct abdominal computed tomography (CT), most imaging studies are reasonably safe in pregnancy. When emergent imaging is needed to prevent maternal morbidity or mortality, any CT sequence with or without contrast is appropriate to pursue. Though new safety data on antiplatelets, antihypertensives, thrombolytics, and antiepileptic drugs have increased options for disease management in pregnancy, unfractionated and low-molecular weight heparin remain the safest options for anticoagulation. Early studies on hypothermia, ketamine, and immunomodulating therapies in pregnancy are promising. In myasthenia gravis, new data on adjunct devices may allow more patients to undergo safe vaginal delivery, avoiding cesarean section and the associated risk of crisis. When difficult decisions regarding preterm delivery arise, recent outcome studies can help inform discussion. Lastly, when the feared complication of maternal death by neurologic criteria occurs, fetal somatic support may help to save at least one life.

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“…Treatment of patients with myasthenia gravis consists of : administration of oral medication, immunomodulating treatment by removal of AChR-ab through plasmapheresis or surgical intervention (thymectomy) [6,7].…”

Section: Abstract: Myasthenia Gravis Achr-ab Thymectomy Acetylcholinementioning

confidence: 99%

The Influence of Thymectomy Over Acetylcoline Antibody Anti-receptor Concentration and Over the Clinical Manifestations on Myasthenia Gravis Patients

Salahoru¹,

Ghiciuc²,

Grigorescu³

et al. 2018

Rev. Chim.

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Myasthenia gravis is an autoimmune disorder which presents a series of clinical manifestations which are generally motor. The hallmark of the disorder is muscle weakness, which typically worsens during physical exercise and improves upon rest. Approximatively 80% of the patients presenting this affection test positive for Acetylcholine antibody anti-receptor (AChR-ab).Treatment of patients with myasthenia gravis consists of:administration of oral medica-tion, immunomodulating treatment by removal of AChR-ab through plasmapheresis or surgical intervention (thymectomy).This article presents a retrospective study in which the authors attempted to identify factors which can influence the effect of thymectomy on AChR-ab titration and on the clinical presentation of the patients suffering with myasthenia gravis.

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Successful use of sugammadex for caesarean section in a patient with myasthenia gravis

Cited by 6 publications

References 5 publications

Retrospective evaluation of anaesthesia methods in pregnant women with neurological and neuromuscular syndromes who underwent caesarean section

Retrospective evaluation of anaesthesia methods in pregnant women with neurological and neuromuscular syndromes who underwent caesarean section

Neurocritical Care of the Pregnant Patient

The Influence of Thymectomy Over Acetylcoline Antibody Anti-receptor Concentration and Over the Clinical Manifestations on Myasthenia Gravis Patients

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