“…At present, a variety of techniques have been employed to detect small molecules, including gas chromatography-mass spectrometry (GC-MS) [1], liquid chromatography-mass spectrometry (LC-MS and LC-MS/MS) [2], electrochemical sensors [3][4][5], plasmonic nanosensors [6,7], enzyme-linked immunosorbent assay (ELISA) [8], aptamers-based sensors [9], molecularly imprinted polymers (MIPs) [10], microfluidic [11,12], surface plasmon resonance (SPR) immunosensors [13], surface-enhanced Raman spectroscopy (SERS) sensors [14], etc. Most of the analytical techniques are specific and highly sensitive; however, they are too time consuming, laborious and complicated, requiring a professional staff and expensive equipment to enable to detect analytes.…”