Hand, foot, and mouth disease in adults caused by Coxsackievirus B1-B6

Hand-Foot-Mouth Disease in an Adult

“…The typical presentation in children is an initial flu-like illness, which is later associated with painful ulcers in the oral cavity and painful vesicles on the palms and soles of the feet. In the adult population, more cases have been described in the last 10 years [ 2 , 5 ]. The diagnosis of HFMD in adults is imminently clinical since virus culture and laboratory identification requires specialized laboratories [ 5 , 6 ].…”

“…Hand-foot-mouth disease (HFMD) is a common, highly contagious infectious disease usually occurring during childhood (usually under 10 years old) [1,2]. It is most frequently caused by coxsackievirus-A16 and enterovirus-A71 with reports of coxsackievirus B1-B6 increasing in adults [2][3][4][5][6]. More recently, worldwide outbreaks of atypical presentation in adulthood associated with the coxsackie-A6 virus have been reported [4][5][6].…”

“…Hand-foot-mouth disease (HFMD) is a common, highly contagious infectious disease usually occurring during childhood (usually under 10 years old) [ 1 , 2 ]. It is most frequently caused by coxsackievirus-A16 and enterovirus-A71 with reports of coxsackievirus B1-B6 increasing in adults [ 2 - 6 ].…”

“…Enteroviruses are responsible for a heterogeneous group of diseases and their transmission is usually by the fecal-oral route, ingestion of fecal material, and respiratory secretions containing the virus [ 4 , 2 ]. After ingestion, there is viral replication in the lymphoid tissue of the pharynx and intestine, spreading posteriorly [ 4 ].…”