Etanercept-induced palisaded neutrophilic granulomatous dermatitis

Palisaded neutrophilic granulomatous dermatitis as a paradoxical adverse reaction following tocilizumab use

“…There are conflicting reports of PNGD/IGD occurrence with etanercept, tumor necrosis factor‐α (TNF‐α) inhibitor for RA management, and etanercept treatment for IGD 7–9 …”

“…Although there are reports of PNGD or IGD occurrence following biological anti‐rheumatoid arthritis (RA) therapy, these anti‐rheumatoid therapeutic agents are used for PNGD or IGD treatment 5–9 . Here, we report a case of PNGD of the head that developed as a paradoxical adverse reaction following the administration of tocilizumab, an interleukin‐6 (IL‐6) inhibitor.…”