Necrolytic migratory erythema associated with painful plantar keratoderma. A new diagnostic clue for this paraneoplastic syndrome?

Recurrent pruritic polymorphic lesions associated with weight loss

“…Glucagon also causes deficiencies in vitamin B and nutrients such as zinc, which can contribute to increased levels of arachidonic acid, prostaglandins, and leukotrienes, and thus, predisposes them to develop deficiencies such as Necrolytic migratory erythema (NME) and the classic epidermal necrolysis. 1 , 5 E. Manifestations are a consequence of inadequate NAD and NADP levels to maintain cellular energy transfer reactions; tissues with high turnover rates, such as the skin, are especially affected. – Incorrect.…”

“…Glucagon also causes deficiencies in vitamin B and nutrients such as zinc, which can contribute to increased levels of arachidonic acid, prostaglandins, and leukotrienes, and thus, predisposes them to develop deficiencies such as Necrolytic migratory erythema (NME) and the classic epidermal necrolysis. 1 , 5 …”